| 人补体C4的RFLP与HLA分型之间关系的探讨 |
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| 引用本文： | 张曙云.人补体C4的RFLP与HLA分型之间关系的探讨[J].科技通报,1996,12(1):61-64. |
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| 作者姓名： | 张曙云 |
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| 作者单位： | 解放军杭州疗养院 |
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| 摘 要： | 应用Ｓｏｕｔｈｅｒｎ印迹杂交法、高压琼脂糖凝胶电泳和标准的微量淋巴细胞毒试验对中国汉族人４４例正常无相关个体进行了Ｃ４基因限制性片段长度多态性（ＲＦＬＰ）、Ｃ４蛋白分型及ＨＬＡ－ＤＲ分型的测定，结果发现Ｃ４ＲＦＬＰ Ａ、Ｂ二种格局在Ｃ４Ｂ＊Ｑ０的表现型上有显著差异（Ｐ〈０．０５）；ＲＦＬＰ Ａ型格局与ＤＲ４相关（Ｐ〈０．０５）。
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| 关 键 词： | 白细胞抗原 补体 RFLP 血清学分型 C4分型 |
Preliminary Discussion of the Relationship Between Complement C_4 Gene RFLP and HLA Serotyping |
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| Zhang Shuyun.Preliminary Discussion of the Relationship Between Complement C_4 Gene RFLP and HLA Serotyping[J].Bulletin of Science and Technology,1996,12(1):61-64. |
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| Authors: | Zhang Shuyun |
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| Institution: | Hangzhou Sanatorium of PLA |
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| Abstract: | The Southern Blot, high-voltage agarose-gel electrophorsis and standard microlymphocytotoxicity tests were to determine the C4 RFLP,C4 allotyping and HLA-DR serotyping in 44 unrelated Chinese from the Nan nationality. The results showed that the two C4 RFLP patterns were significant difference on the phenotype C4B*Q0(P<0.05);and the C4 RFLP A pattern was related to the DR4 (P<0.05). |
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| Keywords: | restriction fragment length polymorphism (RFLP) Human Leucocyte Antigens(HLA) |
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