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胃肠道癌术后化疗T细胞亚群和sIL-2R的比较研究
引用本文:邹忠武,胡加鹏,陈德峰.胃肠道癌术后化疗T细胞亚群和sIL-2R的比较研究[J].孝感职业技术学院学报,2006,9(1):103-105.
作者姓名:邹忠武  胡加鹏  陈德峰
作者单位:湖北职业技术学院网络学院 湖北孝感432000(邹忠武,胡加鹏),华中科技大学同济医学院 湖北武汉430030(陈德峰)
摘    要:目的:比较化疗前后T细胞亚群和sIL-2R水平及术后腹腔化疗和静脉化疗T细胞亚群和sIL-2R水平有无差异。方法:54例胃肠道癌症患者,分两组27例,一组接受腹腔化疗,另一组接受静脉化疗,检测血清中T细胞亚群和sIL-2R水平。结果:化疗后血清CD3、CD4和sIL-2R水平较化疗前明显下降(P<0.01)。CD3、CD4、CD8在两治疗组之间相似(P>0.01),但sIL-2R水平腹腔化疗低(0.05P
关 键 词:胃肠道癌  化疗  T细胞亚群  sIL-2R  免疫
文章编号:1671-8178(2006)01-0103-03
收稿时间:2005-10-12
修稿时间:2005年10月12

Comparative Research of the Serum T -lymphocyte Subsets (T -LS) and sIL- 2R of Postoperative Chemotherapy of Patients with Gastrointestinal Carcinoma
ZOU Zhong-wu,HU Jia-peng,CHENG De-feng.Comparative Research of the Serum T -lymphocyte Subsets (T -LS) and sIL- 2R of Postoperative Chemotherapy of Patients with Gastrointestinal Carcinoma[J].Journal of Xiaogan Vocational-Technical College,2006,9(1):103-105.
Authors:ZOU Zhong-wu  HU Jia-peng  CHENG De-feng
Institution:1Hubei Vocational Technic College ,Xiaogan ,Hubei432000 ,China ;2Department of General surgery Affiiated Tongji Hospital of Tongji Medical College, Huazhong University Science and Technology ,Wuhan 430030 ,China
Abstract:ObjectiveTo compare the difference of the serum Tlymphocyte subsets(T-LS) and sIL-2R before and after the operation,and compare the effect of early postoperative intraperitoneal chemotherapy(EPIC) with that of intravenous chemotherapy(IVC) on the immunity of patients with gastrointestinal carcinoma(GC).Methods54 patients were divided into two groups each with 27 cases,one group received EPIC and the other IVC,then determine the serum T-lymphocyte subsets(T-LS) and sIL-2R before and after the chemotherapy.ResultsSerum CD3,CD4 and slL-2R in GC patients after the chemotherapy decreased more significantly than those of before the chemotherapy(P<0.01),serum CD3,CD4,CD8 levers were similar between two groups(P>0.1),but mean slL-2R level in EPIC group was lower than that in IVC(0.05
Keywords:gastrointestinal carcinoma  chemotherapy  T-lymphocyte subsets(T-LS)  sIL-2R  immunity
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