| 阿维菌素生物合成及其代谢途径研究进展 |
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| 引用本文： | 梁剑光,黄鹏,徐正军.阿维菌素生物合成及其代谢途径研究进展[J].常熟理工学院学报,2007,21(4):65-70. |
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| 作者姓名： | 梁剑光 黄鹏 徐正军 |
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| 作者单位： | 常熟理工学院,生物与食品工程系,江苏,常熟,215500;华东理工大学,生物反应器工程国家重点实验室,上海,200237;南昌大学,生命科学学院,南昌,330047;山东鲁南制药有限公司,山东,临沂,216676 |
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| 摘 要： | 阿维菌素(avermectin)是由阿维链霉菌(Streptomyces avermitilis)产生的一种具有杀虫活性的大环内酯类抗生素,在农业和畜牧业中应用广泛。本文综述了有关阿维菌素生物合成以及阿维菌素育种和代谢工程方面的最新研究进展。
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| 关 键 词： | 阿维菌素 生物合成 代谢途径 研究进展 |
| 文章编号： | 1008-2794（2007）04-0065-06 |
| 收稿时间： | 2007-02-11 |
| 修稿时间： | 2007年2月11日 |
New Research Progress of Avermectin Biosynthesis Pathway and the Metabolic Engineering |
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| LIANG Jian-guang,HUANG Peng,XU Zheng-jun.New Research Progress of Avermectin Biosynthesis Pathway and the Metabolic Engineering[J].Journal of Changshu Institute of Technology,2007,21(4):65-70. |
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| Authors: | LIANG Jian-guang HUANG Peng XU Zheng-jun |
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| Institution: | 1. Changshu Institute of Technology, ChangShu 215500, China; 2. State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China; 3. School of Life Science, Nanchang University, Nanchang 330047, China; 4. Medical Factory of the South Shandong, Linyi 276000 ,China |
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| Abstract: | Avermectin,produced by Streptomyces avermitilis,is a group of pentacyclic lactone antibiotics which have been widely used as antiparasitic drugs in veterinary and agricultural fields.Based on large numbers of latest references,the biosynthesis pathway of avermectin and the metabolic engineering new research progress in this paper have been discussed. |
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| Keywords: | avermectin biosynthesis pathway metabolic engineering research progress |
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