| 运动性骨骼肌损伤相关指标的实验研究 |
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| 引用本文： | 宋卫红,汤长发,梁小文,廖艳萍.运动性骨骼肌损伤相关指标的实验研究[J].首都体育学院学报,2011,23(2):184-187,192. |
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| 作者姓名： | 宋卫红 汤长发 梁小文 廖艳萍 |
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| 作者单位： | 1. 湖南人文科技学院,湖南娄底,417000
2. 湖南师范大学体育学院,湖南长沙,410082 |
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| 基金项目： | 湖南省自然科学基金资助课题(06JJ2073); 湖南省教育厅科研课题资助项目 |
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| 摘 要： | 探讨血清肌酸激酶(CK)、乳酸脱氢酶(LDH)以及波形蛋白(Vimentin)与骨骼肌损伤的关系,将50只8周龄SD大鼠随机分为安静组(C)和运动组(B1,B2,B3,B4),运动组进行重复3 d的力竭性离心运动,电镜和光镜检测骨骼肌损伤病理生理变化,分光光度法检测大鼠血清CK、LDH的变化和免疫组化检测波形蛋白的表达。结果显示:1)血清CK、LDH出现时程变化,并与骨骼肌损伤出现了一致性;2)波形蛋白免疫反应分值呈现时程性。结论:1)CK可作为骨骼肌损伤的间接指标;2)波形蛋白的表达暗示着骨骼肌损伤后的再生。
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| 关 键 词： | 运动性骨骼肌损伤 肌酸激酶 乳酸脱氢酶 波形蛋白 时程 |
Research on Related Indexes of Exercise-induced Skeletal Muscle Damage |
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| SONG Weihong,TANG Changfa,LIANG Xiaowen,LIAO Yanping.Research on Related Indexes of Exercise-induced Skeletal Muscle Damage[J].Journal of Capital College of Physical Education,2011,23(2):184-187,192. |
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| Authors: | SONG Weihong TANG Changfa LIANG Xiaowen LIAO Yanping |
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| Institution: | SONG Weihong1,TANG Changfa2,LIANG Xiaowen2,LIAO Yanping2 1.Hunan Institute of Humanities,Science and Technology,Loudi 417000,China,2.College of Physical Education,Hunan Normal University,Changsha 410082,China. |
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| Abstract: | The purpose of this study was to discuss the relation between serum creatine kinase,serum lactate dehydrogenase,the expresstion of vimentin and skeletal muscle damage.50 male SD rats aged at 8-week-old randomly divided into control group(C) and training group(B1,B2,B3,B4),the training group run for exhaust on a treadmill every day.After repeated training for three days,the pathological and physiological muscle is observed by electron microscope and optical microscope,the activity of serum creatine kinase,se... |
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| Keywords: | EIMD serum creatine kinase serum lactate dehydrogenase expression of vimentin time course |
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