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不同负荷运动训练对小鼠免疫功能影响的实验研究
引用本文:许弟群,林玲,梁惠娟,刘飞,曹芳.不同负荷运动训练对小鼠免疫功能影响的实验研究[J].吉林体育学院学报,2011,27(1):73-75.
作者姓名:许弟群  林玲  梁惠娟  刘飞  曹芳
作者单位:1. 漳州师范学院体育系,福建漳州,363000;上海体育学院运动科学学院,上海200438
2. 漳州师范学院体育系,福建漳州,363000
基金项目:福建省教育厅资助项目,福建省大学生创新性实验计划项目
摘    要:为研究运动训练对机体免疫功能的影响以及为针对性的干预手段提供实验依据。通过对小鼠进行为期6周的不同负荷的游泳训练,采用氚标记胸腺嘧啶掺入法(3H-TdR)测小鼠脾淋巴细胞转化;流式细胞仪对T淋巴细胞亚群进行分型。结果显示:经过6周的游泳训练后,45min训练组在淋巴细胞增殖反应、NK、CD3、CD4、CD4/CD8显著高于对照组和力竭组(P〈0.01),CD8与对照组比较有上升趋势,无显著意义,但显著低于力竭组(P〈0.01);而力竭组在淋巴细胞增殖反应、NK、CD3、CD4、CD4/CD8显著低于对照组和45min训练组(P〈0.05),CD8显著高于对照组和45min训练组(P〈0.01)。实验表明:大负荷的运动训练将导致机体免疫功能下降;而适当运动有利于机体免疫功能增强,提高抗感染能力。

关 键 词:运动训练  小鼠  免疫功能

Effect on Immunologic Function in Mice by Different Exercises
Xu Diqun,Lin Ling,Liang Huijuan,Liu Fei,Cao Fang.Effect on Immunologic Function in Mice by Different Exercises[J].Journal of Jilin Institute of Physical Education,2011,27(1):73-75.
Authors:Xu Diqun  Lin Ling  Liang Huijuan  Liu Fei  Cao Fang
Institution:Xu Diqun1,2,Lin Ling1,Liang Huijuan1,Liu Fei1,Cao Fang1(1.P.E.Department Zhangzhou Normal University,Zhangzhou,363000,Fujian China,2.Department of Sports Science,Shanghai Sport University,Shanghai,200438,China)
Abstract:The purpose of the research was to explore the effect of immunologic function and provide the means of intervention.33 male Balb/c mice were divided into three groups randomly.The controled group(n=10) was sedentary.The 45min training group(n=10) and the overtraining group(n=13,3 mice died during training) were forced to receive acclimatization training in the first week,then the 45min training group and the overtraining group were trained for 45min and to be exhausted per day respectively in the following ...
Keywords:exercise  mice  immunologic function  
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