| 低强度循环载荷训练对髌骨髌腱结合部损伤和髌骨微细结构的影响 |
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| 引用本文： | 王博,王琳.低强度循环载荷训练对髌骨髌腱结合部损伤和髌骨微细结构的影响[J].成都体育学院学报,2016(2):88-92. |
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| 作者姓名： | 王博 王琳 |
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| 作者单位： | 北京体育大学运动康复系,北京,100084 |
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| 基金项目： | 国家自然科学基金项目(30871209)。 |
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| 摘 要： | 目的：：本研究利用循环载荷动物模型,比较休息和低强度运动对髌骨髌腱结合部( patella－patella tendon junction, PPTJ)损伤及对髌骨的影响。实验方法：12只成年雌性新西兰大白兔,随机筛选分组分为4周循环载荷组(LD－RST,n=6),8周循环载荷组(LD－LI,n=6),左后肢进行实验,右后肢为空白对照。实验过程中,前4周两组实验动物统一接受强度为7.17N／S共24小时的循环载荷。在实验的第4周后,LD－RST组停止实验,LD－LI组将强度改为4.2N／共24小时的循环载荷。8周后所有动物统一进行取材,将取材后组织进行Micro－CT进行并进行H&E染色,使用图像采集系统进行组织学分析。结果：H&E染色测量纤维软骨带厚度LD－LI组和LD－RST组没有显著差异,LD－LI组的胶原排列比LD－RST组更加紧密整齐。骨量和骨小梁结果显示实验组和对照组没有显著差异。结论：4周休息不能促进髌腱结合部损伤的恢复。4周低强度的循环载荷没有加重损伤和髌骨增生,并且对肌腱的重建修复具有促进作用。
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| 关 键 词： | 髌骨髌腱结合部损伤 循环载荷 损伤修复 |
The Effect of Low Intensity Cyclical Load on the Patella-patella Tendon Junction Injury and Patella Microstructure |
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| WANG Bo,WANG Lin.The Effect of Low Intensity Cyclical Load on the Patella-patella Tendon Junction Injury and Patella Microstructure[J].Journal of Chengdu Physical Education Institute,2016(2):88-92. |
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| Authors: | WANG Bo WANG Lin |
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| Abstract: | Objective:This study was to compare the effects of rest and low intensity exercise on tendon patella-pa-tella junction ( PPTJ) injury and patella with a cyclic loading animal injury model. Experiment design:12 adult female New Zealand white rabbits were randomly assigned to a four-week cyclical load group ( LD-RST, n =6) and a 8-week cyclical load group (LD-LI, n =6). During the experiment in the first 4 weeks, the two groups of rabbits received cyclical load of 7. 17N/S·24 hours. After four weeks, the experiment on the LD-RST group was stopped and the load on the LD-LI group was changed into 4. 2N/S·24 hours. After 8 weeks, tissues were collected from all the rabbits. The collected tissues were first scanned by Micro-CT and treated by H&E staining and then used for histological analysis by the image acquisition system. Results: There was no significant difference between the LD-LI group and the LD-RST group in the thickness of the fibrocartilage by H&E staining, and the collagen array in the LD-LI group is tighter and more regular than the LD-RST group. There is no significant difference in patellar microstructure between the experimental group and the con-trol group. Conclusion:4 weeks of rest can not promote the recovery of bone tendon junction injury. 4 weeks of low intensity of cyclic loading did not aggravate the damage and patella hyperplasia, and can promote the tendon reconstruction and repair. |
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| Keywords: | Tendon Patella-patella Junction ( PPTJ) Injury Cyclical Load Tendon Repair |
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