| 有氧运动对糖尿病患者T细胞亚群及血清sIL-2R水平影响的研究 |
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| 引用本文： | 王玉,左天香,邓文骞,王传恩.有氧运动对糖尿病患者T细胞亚群及血清sIL-2R水平影响的研究[J].成都体育学院学报,2006,32(5):90-92. |
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| 作者姓名： | 王玉 左天香 邓文骞 王传恩 |
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| 作者单位： | 成都体育学院运动医学系,四川,成都,610041 |
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| 基金项目： | 四川省科技厅应用基础资助项目(05JY009729) |
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| 摘 要： | 选择年龄31~55岁的Ⅱ型糖尿病患者,38人为实验对象。同时选取同龄的健康男性22人作为对照,抽取静脉血进行CD4 、CD8 及sIL-2R检查。指导糖尿病患者进行12周的有氧运动,其中32人顺利完成运动后再次抽取静脉血进行CD4 、CD8 及血清sIL-2R检查。结果:与对照组相比运动前糖尿病患者CD4 、CD8 无明显改变,但CD4 /CD8 明显降低,血清sIL-2R值明显升高。12周有氧运动完成后,糖尿病患者CD4 /CD8 比值明显升高而血清SIL-2R值明显降低。结论:有氧运动可能通过提高CD4 /CD8 比值并降低血清sIL-2R水平来改善糖尿病患者的细胞免疫功能。
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| 关 键 词： | 有氧运动 糖尿病 T细胞亚群 可溶性白细胞介素-2受体 |
| 文章编号： | 1001-9154（2006）05-0090-03 |
| 收稿时间： | 2006-07-18 |
| 修稿时间： | 2006年7月18日 |
Research on the Effect of Aerobic Exercise on T-cell Subsets and Level of Serum Sil-2R With Diabetes |
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| WANG Yu, et al.Research on the Effect of Aerobic Exercise on T-cell Subsets and Level of Serum Sil-2R With Diabetes[J].Journal of Chengdu Physical Education Institute,2006,32(5):90-92. |
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| Authors: | WANG Yu |
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| Institution: | Sports Medical Department, Chengdu Sport University, Chengdu 610041 |
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| Abstract: | Methods: 38 subjects of 2 diabetes men aged 31~35 are assigned to 12 weeks of aerobic exercise training.22 normal men of the same age are assigned as control group and draw blood to test CD4 ,CD8 and sIL-2R before and after instructing the patients to do 12-week aerobic exercise training of 32 patients who complete the exercise.Results: Comparing with control group,the CD4 ,CD8 of type 2 diabetes do not change obviously,but the CD4 /CD8 ratios decreased and serum SIL-2R decreased obviously.After 12-week exercise training,the level of the plasma sIL-2R decreased and CD4 /CD8 ratios increased in patients with type 2 diabetes.Conclusion: the aerobic exercise can improve the function of cell-mediated immunity of type 2 diabetes through decreasing the level of serum sIL-2R and increasing CD4 /CD8 ratios. |
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| Keywords: | aerobic exercise diabetes T-cell Subsets sIL-2R |
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