| 长时间大强度游泳训练对大鼠大脑皮质NE、5-HT的影响 |
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| 引用本文： | 贾龙,袁琼嘉.长时间大强度游泳训练对大鼠大脑皮质NE、5-HT的影响[J].成都体育学院学报,2007,33(1):92-95. |
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| 作者姓名： | 贾龙 袁琼嘉 |
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| 作者单位： | 1. 韶关学院体育学院,广东,韶关,512005
2. 成都体育学院运动医学系,四川,成都,610041 |
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| 摘 要： | 通过长时间大强度游泳训练,观察大鼠组织学结构改变及大脑皮质NE、5-HT表达情况.结果显示:对照组大脑皮质结构正常,可见NE、5-HT在大脑皮质微血管、神经元细胞的胞体和轴突有阳性表达,而且血管表达多于神经细胞表达.过度训练组可可见明显微循环障碍,神经元细胞周围空泡变,5-HT表达面积、表达强度和表达水平均高于对照组,但元显著性.实验表明NE、5-HT参与了运动性中枢疲劳的发生和发展.NE、5-HT通过直接或间接影响脑微循环和神经细胞功能和结构,使运动能力进一步下降,导致运动性中枢疲劳.
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| 关 键 词： | 去甲肾上腺素(NE) 5-羟色胺(5-HT) 大脑皮质 运动性中枢疲劳 |
| 文章编号： | 1001-9154（2007）01-0092-04 |
| 收稿时间： | 2006-07-18 |
| 修稿时间： | 2006年7月18日 |
Effects of Sustained Exhausted Swimming on NE5-TH Expression in Rat Cerebral Cortex |
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| JIA Long,YUAN Qiongjia.Effects of Sustained Exhausted Swimming on NE5-TH Expression in Rat Cerebral Cortex[J].Journal of Chengdu Physical Education Institute,2007,33(1):92-95. |
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| Authors: | JIA Long YUAN Qiongjia |
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| Institution: | Physical Education Department of Shaoguan University, Shaoguan, Guangdong, 512005 |
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| Abstract: | SD rats were treated with overloaded swimming training to observe the changes of cerebral cortex microstructure,and NE&5-HT expression's location.Findings indicated that the microstructures in cerebral cortex were normal and the expression of NE&5-HT were positive on neurons and endothelial cells in control group(C group).However,there were significant abnormal changes of microstructures in overloaded group(O group).Meanwhile,the 5-HT positive area,intensity and level were increased without significance.It is possible that NE&5-HT may play important roles in the occurrence and development of sports CNS fatigue.NE&5-HT can affect the function and structure of microvessels and neurons in cerebral cortex.Under the condition,motor ability decreased significantly,including sports CNS fatigue. |
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| Keywords: | norepinephrine(NE) 5-hydroxytryptamine(5-HT) cerebral cortex sports central nervous system(CNS)fatigue |
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