| 不同强度跑台运动对大鼠学习记忆能力及海马CA3区突触超微结构的影响 |
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| 引用本文： | 龚云.不同强度跑台运动对大鼠学习记忆能力及海马CA3区突触超微结构的影响[J].北京体育大学学报,2012,35(3):63-66. |
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| 作者姓名： | 龚云 |
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| 作者单位： | 西北师范大学体育学院 |
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| 基金项目： | 西北师范大学青年教师科研能力提升计划项目(编号:SKQNYB10033) |
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| 摘 要： | 探讨不同强度跑台运动对大鼠学习记忆能力及海马CA3区超微结构的影响。40只Wister大鼠随机被分为4组(对照组、低强度运动组、中强度运动组、高强度运动组,各10只),按各自强度运动60 d后,通过一次性被动回避反应实验,逐只测量其步入潜伏期的时间(STL);后每组任选5只大鼠,取右侧海马CA3区按常规方法制作超薄切片,60K倍透射电镜观察并拍照,Motic Images Advanced 3.1软件测量相关突触界面结构。结果表明:低强度运动组大鼠,电击后24 h步入潜伏期的时间显著延长(P0.05),海马CA3区突触后膜致密物质非常显著增厚(P0.01)。突触界面呈现平直型、正向弯曲型和负向弯曲型三种,以平直型为主。由此可见,低等强度运动可增强记忆能力,并影响海马CA3区神经元突触结构发生可塑性变化,突触后膜致密物质厚度与记忆能力呈正相关。
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| 关 键 词： | 学习记忆 突触 海马CA区 超微结构 跑台运动 |
| 收稿时间： | 2010/12/20 0:00:00 |
Effect of different Intensity Exercises in Treadmill on Learning and Memory and The Synaptic Ultrastructure in Hippocampal CA3 Area in Rats |
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| GONG Yun.Effect of different Intensity Exercises in Treadmill on Learning and Memory and The Synaptic Ultrastructure in Hippocampal CA3 Area in Rats[J].Journal of Beijing Sport University,2012,35(3):63-66. |
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| Authors: | GONG Yun |
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| Institution: | GONG Yun(P.E.Dept.,Northwest Normal University,Lanzhou 730070,Gansu China) |
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| Abstract: | Effect of the different intensity treadmill exercise on learning and memory ability and hippocampal CA3 area ultrastructure was studied in rats.40 SD rats were randomly divided into four groups(control group,low-intensity exercise group,medium-intensity exercise group and high-intensity exercise group),after 60d exercise according to their respective intensity,through the one-trial passive avoidance response,the time to step-through lateney(STL) of rats was measured in every exercise group.Then 5 rats were chosen from every group,through normal ultrathin section made method,hippocampal CA3 area was observed under JEM-1230EX transmission electron microscope and photographed.The results showed that: 24 hours of STL period after electrical shock was significantly longer(P<0.05) in low-intensity exercise group rats,and the hippocampal CA3 area postsynaptic density material became significantly thicker(P<0.01).The curved type of synaptic interface could be divided into positively curved,negatively curved and flat,the flat type was the main.As a result,low-intensity exercise can increase memory capacity,and make the neuron synapse occurring plastic changes in the hippocampal CA3 area.The thickness of postsynaptic density material came into being a positive correlation with the strength of memory. |
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| Keywords: | learning and memory synapse hippocampus CA3 area ultrastructure treadmill exercise |
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