| 耐力训练与中药干预对大鼠骨骼肌雄激素受体表达的影响 |
| |
| 引用本文： | 王启荣,乔莉,周丽丽,高红,许葆华,杨则宜.耐力训练与中药干预对大鼠骨骼肌雄激素受体表达的影响[J].北京体育大学学报,2009(12). |
| |
| 作者姓名： | 王启荣 乔莉 周丽丽 高红 许葆华 杨则宜 |
| |
| 作者单位： | 国家体育总局运动医学研究所;北京康比特运动营养研究所; |
| |
| 基金项目： | 国家科技攻关计划奥运科技专项(2002BA904B16)资助 |
| |
| 摘 要： | 目的:探讨耐力运动和补充益气补肾中药对大鼠血清和睾丸睾酮水平以及骨骼肌AR mRNA表达的的影响。方法:50只Wistar大鼠随机分为安静对照组(n=10)、安静服药组(n=10)、训练组(n=15)和训练服药组(n=15)。经6周递增负荷游泳训练后,使用放免法测定大鼠睾丸和股四头肌匀浆总睾酮水平,利用RT-PCR方法检测大鼠深层股四头肌AR mRNA的表达水平。采用One-way Anova对组间数据进行比较,采用析因方差分析揭示训练和中药两种因素对所测指标的影响。结果:未服药训练大鼠的血清和睾丸组织睾酮水平明显下降(P<0.05);服用中药的运动大鼠血清和睾丸睾酮浓度未下降。训练对大鼠骨骼肌AR基因的表达有极显著的影响(p<0.001);中药同训练因素一样,亦能明显提高AR基因的表达水平,但是效应程度低于训练因素(p<0.01);两者的交互作用对AR基因表达的影响同样显著(p<0.01)。结论:长时间适应性训练和补充益气补肾中药可以促进增强大鼠股四头肌(Ⅱ型肌纤维为主)AR mRNA的表达。
|
| 关 键 词： | 耐力训练 中药 骨骼肌 雄激素受体 |
Effects of Endurance Training and Chinese Medicine Compound for Invigorating Qi and Tonifying the Kidney on Skeletal Muscular Androgen Receptor mRNA Expression in Rats |
| |
| WANG Qi-rong,QIAO Li,ZHOU Li-li,GAO Hong,XU Bao-hua,YANG Ze-yi.Effects of Endurance Training and Chinese Medicine Compound for Invigorating Qi and Tonifying the Kidney on Skeletal Muscular Androgen Receptor mRNA Expression in Rats[J].Journal of Beijing Sport University,2009(12). |
| |
| Authors: | WANG Qi-rong QIAO Li ZHOU Li-li GAO Hong XU Bao-hua YANG Ze-yi |
| |
| Institution: | WANG Qi-rong1,QIAO Li2,ZHOU Li-li1,GAO Hong1,XU Bao-hua1,YANG Ze-yi1(1.National Institute of Sports Medicine,Beijing 100029,China,2.Beijing Competitor Institute of Sports Nutrition,China) |
| |
| Abstract: | The Objective of the study is to explore the effects of endurance training and the use of Chinese Medicine Compound for Invigorating Qi and Tonifying the Kidney on AR expression level of skeletal muscle in rats.Methods: 50 Wistar male rats were randomly divided into 4 groups: sedentary group(S,n=10),sedentary with medicine group(SM,n=10),training group(T,n=15) and training with medicine group(TM,n=15).After 6 weeks swimming training,testicular and muscular(quadriceps femoris) homogenate testosterone level o... |
| |
| Keywords: | endurance training Chinese medicine compound skeletal muscle androgen receptor |
| 本文献已被 CNKI 等数据库收录！ |
|
