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| 长期运动训练对运动性低血色素大鼠组织转铁蛋白及转铁蛋白受体基因表达的影响 | |
| 引用本文： | 曹建民,田野,赵杰修,郑弘溶,金丽,赵宁宁.长期运动训练对运动性低血色素大鼠组织转铁蛋白及转铁蛋白受体基因表达的影响[J].北京体育大学学报,2006,29(11):1492-1494. |
| 作者姓名： | 曹建民 田野 赵杰修 郑弘溶 金丽 赵宁宁 |
| 作者单位： | 1. 北京体育大学,北京,100084 2. 国家体育科学研究所,北京,100061 3. 武汉体育学院,湖北,武汉,430079 4. 徐州师范大学体育学院,江苏,徐州,221116 |
| 基金项目： | 科技部重点项目 , 国家自然科学基金 |
| 摘 要： | 了解发生运动性低血色素时转铁蛋白及转铁蛋白受体基因表达的变化对深入研究运动性贫血的发生机制具有重要的意义.实验结果表明:长期运动训练导致运动性低血色素大鼠肌肉组织中转铁蛋白和转铁蛋白受体基因表达均显著增加,表明运动训练造成的运动性低血色素大鼠肌肉中铁代谢紊乱,肌肉应激性使转铁蛋白以及转铁蛋白受体表达增加,以促进肌肉对铁的吸收;运动性低血色素大鼠肝脏组织中转铁蛋白基因表达均显著下降,这可能是由于肝脏铁储量增加而导致的转铁蛋白基因表达的适应性的降低有关;运动训练导致运动性低血色素大鼠转铁蛋白和转铁蛋白受体表达具有组织特异性,转铁蛋白受体基因表达与组织铁代谢关系密切. |
| 关 键 词： | 运动训练 运动性低血色素 转铁蛋白 转铁蛋白受体 基因表达 运动训练 运动性 血色素 大鼠组织 白及 转铁蛋白受体 基因表达 影响 Rats Serum mRNA Expression Gene Transferrin Receptor 关系 铁代谢紊乱 组织特异性 适应性 肝脏铁 肝脏组织 铁的吸收 |
| 文章编号： | 1007-3612(2006)11-1492-03 |
Effects of Long-term Exercises on Transferrin and Transferrin Receptor Gene mRNA Expression of Athletic Low Haemoglobin Serum Rats |
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| CAO Jian-min,TIAN Ye,ZHAO Jie-xiu,ZHENG Hong-rong,JIN Li,ZHAO Ning-ning.Effects of Long-term Exercises on Transferrin and Transferrin Receptor Gene mRNA Expression of Athletic Low Haemoglobin Serum Rats[J].Journal of Beijing Sport University,2006,29(11):1492-1494. | |
| Authors: | CAO Jian-min TIAN Ye ZHAO Jie-xiu ZHENG Hong-rong JIN Li ZHAO Ning-ning |
| Abstract: | Knowing the changes of transferrin and transferrin Receptor gene mRNA expression when the athletic low haemoglobin serum happens is very important to explore the mechanism of sports anemia.The results shows that the transferrin and transferrin receptor gene mRNA expression of the athletic low haemoglobin serum rat's musculature obviously increases after long-term exercises which indicates that iron metabolism turbulence can be caused by exercises.Transferrin and trnasferrin receptor gene mRNA expression can be enhanced because of muscle stress to improve the assimilation of iron,while transferrin receptor gene mRNA Expression has a different change in liver tissue and this may be due to the increasing of liver iron to lead the adaptive depression of transferrin receptor gene mRNA expression.It is specificity to rransferrin and rransferrin receptor gene mRNA expression on athletic low haemoglobin serum rats induced by exercises,and it has a close relationship between rransferrin receptor gene mRNA expression and the metabolization of tissue iron. |
| Keywords: | exercises athletic low haemoglobin serum Transferrin Transferrin Receptor Gene mRNA Expression |
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