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儿童最大有氧能力、跑节省化以及心脏左室结构与线粒体DNA基因多态性的关联研究
引用本文:马力宏,张薇,陈青,陈家琦.儿童最大有氧能力、跑节省化以及心脏左室结构与线粒体DNA基因多态性的关联研究[J].天津体育学院学报,2001,16(1):13-16.
作者姓名:马力宏  张薇  陈青  陈家琦
作者单位:1. 天津体育学院实验中心,
2. 美国特拉华州立大学
3. 天津体育学院运动医学研究所,
基金项目:教育部留学回国人员启动资金资助
摘    要:摘要:对36名男性儿童的最大有氧能力、跑节省化以及心脏左室形态结构与线粒体DNAD—Loop区遗传多态性作了关联分析。实验结果支持我们早先的研究结论,即线粒体DNAD—Loop区可能对人类VO2azx有一定程度的调控作用,而与RE无关。对于青春发育前期的男性儿童,VO2azx与RE呈显著相关关系,但二者的生理机制可能会有差异。中枢机制是决定青春发育前期儿童VO2azx自然值的重要因素。

关 键 词:最大摄氧量  跑节省化  心室结构  线粒体DNA  儿童
文章编号:1005-0000(200 1)01-0013-04
修稿时间:1/3/2001 12:00:00 AM

RELATIONSHIP BETWEEN VO2max, RUNNING ECONOMY,ECHOCARDIOGRAPHIC PROFILES AND mtDNA GENE POLYMORPHISM IN CHILDREN
MA Li-hong,ZHANG Wei,CHEN Qing,CHEN Jia-qi.RELATIONSHIP BETWEEN VO2max, RUNNING ECONOMY,ECHOCARDIOGRAPHIC PROFILES AND mtDNA GENE POLYMORPHISM IN CHILDREN[J].Journal of Tianjin Institute of Physical Education,2001,16(1):13-16.
Authors:MA Li-hong  ZHANG Wei  CHEN Qing  CHEN Jia-qi
Institution:Laboratory Center, Tianjin Institute of Physical Education, Tianjin 300381, China;Delaware State University , U . S. A;Laboratory Center, Tianjin Institute of Physical Education, Tianjin 300381, China;Tianjin Research Institute of Sports Medicine, Tianjin 300381, China
Abstract:VO 2max ,running economy, echocardiographic profiles and mtDNA D loop RELP were determined in 36 pre pubertal boys. The results of this study are consistent with those previously published by us, i.e. the variation of human VO 2max may be explained partially by some genetic profiles in mtDNA D loop region, whereas it seems to have no effect on running economy.VO 2max is associated with running economy significantly for boys, but the two parameters may not be controlled by the same mechanism. Besides the initial values of the maximal aerobic power in the young subjects are likely affected mainly by central mechanism.
Keywords:Vo2max  running economy  echocardiographic profile  mtDAN  children
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