| 游泳运动锻炼对Ⅱ型糖尿病大鼠血清和骨骼肌musclin含量的影响 |
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| 引用本文： | 唐智明,邓玉强.游泳运动锻炼对Ⅱ型糖尿病大鼠血清和骨骼肌musclin含量的影响[J].西安体育学院学报,2011,28(5):594-597. |
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| 作者姓名： | 唐智明 邓玉强 |
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| 作者单位： | 南通大学体育科学学院,江苏南通,226007 |
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| 摘 要： | 目的研究Ⅱ型糖尿病大鼠血清和骨骼肌musclin含量的变化,并探讨运动训练对Ⅱ型糖尿病大鼠血清和骨骼肌musclin含量的影响。方法 SD大鼠随机分为正常对照组(C,n=8)、糖尿病对照组(DM,n=9)和糖尿病运动锻炼组(DME,n=10)。检测大鼠空腹血糖和血清、腓肠肌musclin含量。结果与C组相比,DM组大鼠血清胰岛素含量和胰岛素敏感性明显降低,空腹血糖水平显著增加;且血清和腓肠肌musclin含量显著升高;与DM组相比,DME组大鼠血清胰岛素和胰岛素敏感性显著升高,空腹血糖水平显著降低;且血清和腓肠肌musclin含量显著降低。结论 Musclin在Ⅱ型糖尿病过程中可能起着非常重要的作用;长期的有氧运动锻炼可能通过降低Ⅱ型糖尿病大鼠血清和腓肠肌musclin的含量,增加骨骼肌从血液中摄取葡萄糖的能力,从而降低血糖。
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| 关 键 词： | musclin 游泳运动锻炼 Ⅱ型糖尿病 大鼠 |
Effects of Swimming Training on Muscling in Serum and Skeletal Muscle of 2 Type Diabetic Rats |
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| TANG Zhi-ming,DENG Yu-qiang.Effects of Swimming Training on Muscling in Serum and Skeletal Muscle of 2 Type Diabetic Rats[J].Journal of Xi'an Institute of Physical Education,2011,28(5):594-597. |
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| Authors: | TANG Zhi-ming DENG Yu-qiang |
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| Institution: | TANG Zhi-ming,DENG Yu-qiang(School of Sport and Science in Nantong University,Nantong 226007,China) |
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| Abstract: | Objective: In order to explore the changes of muscling content in serum and skeletal muscle of type 2 diabetic rats,and explore the effect of exercise training on changes of musclin content.Methods:SD rats randomly named as the control group(C,n=8),Diabitic Mellitus group(DM,n=9)and Diabitic Model Exercise group(DME,n=10).Fast blood glucose(FBG),fast insulin(FINS)and musclin in serum and skeletal muscle were measured.Results:Compared with C group,FINS and insulin sensitive index(ISI) decreased significantly... |
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| Keywords: | musclin swimming training type 2 diabetes mellitus rats |
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