| 有氧运动对老年大鼠学习记忆及海马CA1区一氧化氮合酶表达的影响 |
| |
| 引用本文： | 付芳,崔建梅,于芳.有氧运动对老年大鼠学习记忆及海马CA1区一氧化氮合酶表达的影响[J].体育科学,2011,31(11). |
| |
| 作者姓名： | 付芳 崔建梅 于芳 |
| |
| 作者单位： | 中北大学体育与艺术学院,山西 太原,030051 |
| |
| 摘 要： | 目的:探讨有氧运动对老年大鼠学习记忆能力、血清睾酮及海马CA1区nNOS表达的影响.方法:选择SD雄性老年大鼠,分成老年对照组及有氧训练组.对照组不运动,有氧训练组采用递增负荷训练,连续8周.8周后检测血清睾酮,测试大鼠空间学习记忆能力,对海马CA1区nNOS神经元的数量、面积及灰度进行测量和分析.结果:1)与老年对照组比较,有氧运动组大鼠血清睾酮水平增高(P＜0.05),完成八臂迷宫时间缩短,错误次数显著减少(P＜0.05)；2)与老年对照组比较,有氧运动组海马CAl区nNOS免疫阳性细胞数量和阳性产物面积均增加(P＜0.05).结论:有氧运动可提高老年大鼠的记忆能力,机理可能与长期有氧运动提高老年大鼠的血清睾酮水平及增强大脑海马CA1区nNOS的表达有关.
|
| 关 键 词： | 有氧运动 学习记忆 雄激素 海马 nNOS 鼠 动物实验 |
Influence of the Aerobic Training on Learning and Memory and NOS Expression within Hippocampus CA1 in the Aged Rats |
| |
| FU Fang,CUI Jian-mei,YUFang.Influence of the Aerobic Training on Learning and Memory and NOS Expression within Hippocampus CA1 in the Aged Rats[J].China Sport Science,2011,31(11). |
| |
| Authors: | FU Fang CUI Jian-mei YUFang |
| |
| Institution: | FU Fang,CUI Jian-mei,YU FangSchool of Physical Education,North University of China,Taiyuan 030051,China. |
| |
| Abstract: | Objective:To explore the influence of the aerobic training on learning and memory,the level of serum testosterone,and expression of nNOS within Hippocampus CA1 of brain in the aged rats.Methods:SD aged rats(24-mouth) were chosen and randomly divided into 2 groups:the aged control group and the aerobic training group.The control group kept normal activities and the aerobic training group undertook the 8-week training with progressively increasing load.Then each animal's capability of learning and memory and ... |
| |
| Keywords: | aerobic training learning and memory testosterone Hippocampus CA1 nNOS |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
