| HiHiLo对心功能的影响与ACE基因I/D多态性的关联研究 |
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| 引用本文： | 周多奇,龚莉,胡扬,李燕春,衣龙彦.HiHiLo对心功能的影响与ACE基因I/D多态性的关联研究[J].体育科学,2011,31(11). |
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| 作者姓名： | 周多奇 龚莉 胡扬 李燕春 衣龙彦 |
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| 作者单位： | 1. 安庆师范学院,安徽 安庆,246011
2. 北京体育大学.北京 100084 |
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| 基金项目： | 国家自然科学基金，安徽省教育厅自然科学基金 |
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| 摘 要： | 目的:探讨低氧训练对心脏结构与功能的影响及其与中国人群ACE基因I/D多态性之间的关联性.方法:76名中国北方平原地区汉族男子进行4周高住高练低训( HiHiLo),方案为每日在低氧环境(O2浓度为14.5％～14.8％)中休息10h,每周进行3次75％VO2 max低氧训练(O2浓度为15.4％),其余时间在常氧下训练；HiHiLo前后测定左心室结构与功能相关指标；PCR分析受试者的ACE基因I/D多态性.结果:HiHiLo后心脏结构指标LVM、LVMI、IVSD和PWD都显著性增加(P＜0.05)；训练后安静时、各种负荷时和恢复时EDV、EF、SV、SVI和E/A显著性增加(P＜0.05),HR、CO、COI、Vmn和Vp显著性减小(P＜0.05).HiHiLo前各指标在ACE各基因型间无显著性差异(P＞0.05)；除50 W和150W时HR外,其余心脏结构和功能指标训练后变化在各组间均未见显著性差异(P＞0.05).结论:HiHiLo能使左心室结构和功能呈现良好的顺应性变化；ACE基因型与个体心功能对HiHiLo的敏感性无关.
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| 关 键 词： | ACE基因多态 耐力训练 左心室结构与功能 |
Association between ACE Gene I/D Polymorphism and the Effects of Living High-Exercise High-Training Low on the Cardiac Functions |
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| ZHOU Duo-qi,GONG Li,HU Yang,LI Yan-chun,YI Long-yan.Association between ACE Gene I/D Polymorphism and the Effects of Living High-Exercise High-Training Low on the Cardiac Functions[J].China Sport Science,2011,31(11). |
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| Authors: | ZHOU Duo-qi GONG Li HU Yang LI Yan-chun YI Long-yan |
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| Institution: | ZHOU Duo-qi1,GONG Li1,HU Yang2,LI Yan-chun2,YI Long-yan21.Anqing Teachers College,Anqing 246011,China,2.Beijing Sport University,Beijing 100084,China. |
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| Abstract: | To explore the association between Insertion/Deletion polymorphism of the angiotensin converting enzyme(ACE) gene and the effects of living high-exercise high-training Low(HiHiLo) on the cardiac structure and functions.76 healthy men of Han nationality in northern China underwent HiHiLo training for 4 weeks.Training program was as follows:exposure in hypoxic environment(14.5%~14.8%O_2,10 h/day),three times hypoxic training per week(15.4%O_2),and training at sea level.The structure and function of left ventr... |
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| Keywords: | ACE gene polymorphism endurance training structure and function of left ventricle |
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