| 有氧运动条件下一氧化氮合成与肝脏尿素循环之间关系初探 |
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| 引用本文： | 王冰梅,徐朝晖.有氧运动条件下一氧化氮合成与肝脏尿素循环之间关系初探[J].体育科学,2005,25(5):47-49. |
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| 作者姓名： | 王冰梅 徐朝晖 |
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| 作者单位： | 1. 浙江林学院,旅游与健康学院,浙江,临安,311300
2. 淮北市人民医院,烧伤科,安徽,淮北,235000 |
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| 摘 要： | 以方差分析和线性相关分析方法，探讨补充精氨酸和游泳训练对小鼠血NO(bNO)、血尿素氮(bBUN)和骨骼肌一氧化氮合酶(sNOS)的影响，篮球训练对大学生bNO、bBUN的影响以及小鼠／人肝脏尿素生成与NO合成之间的关系。结果表明：1)补充精氨酸对安静和训练小鼠NO和尿素生成均无显著影响；2)有氧训练使人／小鼠的NO和尿素生成均显著增加，且两者呈高度相关。结论：机体通过有效的自身调节机制，能够满足有氧运动下NO和尿素合成对Arg的需求，不需额外补充；肝脏尿素循环与外周NO合成是相互促进的，这也许是机体在有氧运动条件下对Arg、Cit需求与供应的自身调节机制，即：同肝脏与骨骼肌之间的葡萄糖—丙氨酸循环一样，肝脏与外周NO合成组织间可能存在着高效的“Cit—Arg cycle”。该结论需进一步实验证实。
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| 关 键 词： | 有氧运动 一氧化氮合成 尿素 瓜氨酸-精氨酸循环 鼠 大学生 |
| 文章编号： | 1000-677X(2005)05-0047-03 |
Study on Relation between Nitric Oxide Synthesis and Hepatic Urea Cycle on Condition of Aerobic Exercise |
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| WANG Bing-mei,XU Zhao-hui.Study on Relation between Nitric Oxide Synthesis and Hepatic Urea Cycle on Condition of Aerobic Exercise[J].China Sport Science,2005,25(5):47-49. |
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| Authors: | WANG Bing-mei XU Zhao-hui |
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| Institution: | WANG Bing-mei1,XU Zhao-hui2 1.School of Tourism and Health,Zhejiang Forest University,Lin'an 311300,China,2.Department of Burns Surgeon,Huaibei People's Hospital,Huaibei 235000,China. |
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| Abstract: | Taking mice and graduate students as research subject,this paper probes the effects of Arg supplement on bNO,bBUN and sNOS of mouse,basketball training on human/mice bNO,bBUN by using the method of variance and linear correlation.The result shows that Arg supplement has no significant influence on NO synthesis and urea cycle both in control group and in trained group of mouse.Aerobic training enhances human/mouse bNO and bBUN level and mouse sNOS activity significantly.The concentration of bBUN is correlated with bNO of human/mouse highly and so does bBUN to sNOS of mouse.It suggests that organism can meet the Arg requirement of NO synthesis by effective self-regulation mechanism and dose not need Arg supplement.Urea cycle and NO synthesis are promoted each other.It is the self-regulation mechanism for Arg requirement and provision on condition of aerobic exercise,For example,the glucose-alanine cycle between liver and skeletal muscle and effective Cit-Arg cycle.The above conclusion needs to be further proved. |
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| Keywords: | aerobic exercise nitric oxide synthesis urea cycle Cit-Arg cycle arginine supplement mouse college student |
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