| 运动训练对应激大鼠下丘脑CRH mRNA的影响 |
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| 引用本文： | 李宁川,王金玉,黄美蓉.运动训练对应激大鼠下丘脑CRH mRNA的影响[J].中国体育科技,2006,42(5):82-84. |
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| 作者姓名： | 李宁川 王金玉 黄美蓉 |
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| 作者单位： | 1. 扬州大学,江苏,扬州,225009
2. 中国矿业大学,体育学院,江苏,徐州,221008 |
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| 摘 要： | 为探讨运动训练和应激对大鼠HPA轴的影响,将50只健康雄性SD大鼠随机分为7组,即对照组、电击组、60min运动训练组、急性心理应激组、慢性心理应激组、急性心理应激+运动组、慢性心理应激+运动组。进行10周游泳运动训练,同时分别施加急、慢性心理应激,然后检测大鼠下丘脑CRHmRNA。结果:1)心理应激可激活HPA轴,下丘脑CRHmRNA显著高于对照组。2)与应激组相比,运动+应激组CRHmRNA增加不明显。结论:心理应激作为一种应激源,会引起大鼠较强的心理反应,从而激活HPA轴;中等负荷运动可有效地降低心理应激,提高机体的抗应激能力。
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| 关 键 词： | 运动锻炼 心理应激 鼠 动物实验 |
| 文章编号： | 1002-9826(2006)05-0082-03 |
| 修稿时间： | 2006年2月20日 |
Effect of Athletic Training on CRH mRNA of Psychological Stress Rat |
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| LI Ning-chuan,WANG Jin-yu,HUANG Mei-rong.Effect of Athletic Training on CRH mRNA of Psychological Stress Rat[J].China Sport Science and Technology,2006,42(5):82-84. |
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| Authors: | LI Ning-chuan WANG Jin-yu HUANG Mei-rong |
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| Abstract: | In order to discuss the effect of athletic training and stress on hypothalamo-pituitary-adrenal (HPA) axis,50 healthy SD male rats were randomly divided into 7 group,control group,foot-shocked group,exercise group with 60 minutes,acute psychological stress group,chronic psychological stress,acute psychological stress with exercise group,chronic psychological stress with exercise group.Swimming exercise was done for 10 weeks,while acute and chronic psychological stress was carried on respectively.The CRH mRNA in hypothalamo was tested.The result showed that the psychological stress could activate the HPA axis.The CRH mRNA was significant higher than that of control group.Comparing with stress group,CRH mRNA in exercise with stress group didn't increased obviously.It concluded that as the stress source,psychological stress could induce strong mental reaction,then activate HPA axis.Moderate exercise load could effectively reduce the psychological stress and improve the capacity of anti-stress. |
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| Keywords: | CRH mRNA |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
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