| NF—κB在骨骼肌运动性自由基损伤中的信号转导作用 |
| |
| 引用本文： | 胡少娟,徐晓阳.NF—κB在骨骼肌运动性自由基损伤中的信号转导作用[J].安徽体育科技,2008,29(3):51-53. |
| |
| 作者姓名： | 胡少娟 徐晓阳 |
| |
| 作者单位： | 1. 文山师范高等专科学校体育系,云南,文山,663000
2. 华南师范大学体科院,广东,广州,510000 |
| |
| 摘 要： | 运动会造成细胞内氧自由基生成的增加，使细胞及细胞器功能损伤或者低下。大量的研究表明在自由基对细胞影响的信号转导机制中，核转录因子NF—κB起着重要作用，调节着由线粒体到细胞核的信号转导，进而调节着下游因子的表达，使细胞对由自由基造成的损伤进行应答。
|
| 关 键 词： | 运动 线粒体 NF—κB ROS |
NF-κB And The Exercise-Induced Cell Dysfunction |
| |
| Shao Juanhu,Xiao Yangxu.NF-κB And The Exercise-Induced Cell Dysfunction[J].Journal of Anhui Sports Science,2008,29(3):51-53. |
| |
| Authors: | Shao Juanhu Xiao Yangxu |
| |
| Institution: | Shao Juanhu Xiao Yangxu (Wenshan Teachers\' College,the Department of P.E,Wenshan Yunnan 663000) |
| |
| Abstract: | Exercises cause the production of ROS increased, and this can induce the cell dysfunction. Numerous studies have shown that NF - κB may play an important role in the effect of ROS on cellular signal transduction. NF-κB regulates the signal pathway from mitochondrion to nucleus, and activates the downstream factors, resulting cellular response to the ROS- induced injury. The purpose of this review is to make a statement of the role between NF- κB and exercise- induced call injury induced by ROS. |
| |
| Keywords: | ROS |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
