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基因编辑的技术分析与思考
引用本文:宋秀芳,魏雪梅,郑丽丽,赵亚娟,张可心,刘春光,胥伟华.基因编辑的技术分析与思考[J].中国科学院院刊,2020,35(12):1510-1524.
作者姓名:宋秀芳  魏雪梅  郑丽丽  赵亚娟  张可心  刘春光  胥伟华
作者单位:中国科学院文献情报中心 北京 100190;中国科学院大学 经济与管理学院图书情报与档案管理系 北京 100190;中国科学院遗传与发育生物学研究所 北京 100101;中国科学院种子创新研究院 北京 100101
基金项目:北京市科技成果转化平台建设专项(0020180716)
摘    要:基因编辑技术是当今非常重要的生物工程技术,在生物医药、生物环保和农业生产领域有着极其广泛的应用。文章通过对基因编辑相关专利和期刊文献的分析,从全球主要机构专利申请与发文情况、CRISPR技术专利概况、各国专利发明人的合作关系、技术流向分析、技术构成分析、主要创新主体现状等方面揭示了基因编辑技术的发展现状与趋势;并基于对CRISPR技术的专利分析及其相关重要研发机构的专利布局分析,对我国基因编辑技术在原始性技术创新、产业化进程、国际合作、全球布局等方面提出了对策与建议,为相关领域的研究人员及决策者提供参考。

关 键 词:基因编辑  文献计量  技术构成  技术流向  创新主体
收稿时间:2020/11/30 0:00:00

Analysis and Review on Gene Editing
SONG Xiufang,WEI Xuemei,ZHENG Lili,ZHAO Yajuan,ZHANG Kexin,LIU Chunguang,XU Weihua.Analysis and Review on Gene Editing[J].Bulletin of the Chinese Academy of Sciences,2020,35(12):1510-1524.
Authors:SONG Xiufang  WEI Xuemei  ZHENG Lili  ZHAO Yajuan  ZHANG Kexin  LIU Chunguang  XU Weihua
Institution:National Science Library, Chinese Academy of Sciences, Beijing 100190, China;Department of Library, Information and Archives Management, School of Economics and Management, University of Chinese Academy of Sciences, Beijing 100190, China;Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China;Institute of Seed Innovation, Chinese Academy of Sciences, Beijing 100101, China
Abstract:Gene editing technology is a very important bioengineering technology, which is widely used in biomedicine, biological environmental protection, and agricultural production. Based on the analysis of patents and articles related to gene editing, this study reveals the development status and trend of gene editing technology from the following aspects: Patent application and publication of major global institutions, overview of CRISPR technology patents, cooperation among patent inventors in various countries, analysis of technology flow direction, technology composition, and status of main innovation subjects. Countermeasures and suggestions on the original technology innovation, industrialization process, and international collaboration are put forward for researchers and decision makers in the related fields.
Keywords:gene editing  bibliometrics  technology composition  technology flow direction  technological innovation subject
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