Unusual changes in colostrum composition in lactating Indian women having medical complications during pregnancy—A pilot study |
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| Authors: | S Kaushik S S Trivedi A Jain J Bhattacharjee |
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| Institution: | (1) Department of Biochemistry, Lady Hardinge Medical College & Smt. Sucheta Kriplani Hospital, A-5, Chittranjan Park, 110019 New Delhi;(2) Department of Obstetrics & Gynaecology, Lady hardinge Medical College & Smt. Sucheta Kriplani Hospital, A-5, Chittranjan Park, 110019 New Delhi |
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| Abstract: | Colostrum, the mammary secretion during first 2–4 days of lactation, provides all the essential components of nutrition and
passive immunity required by the newborn. Pregnancy induced hypertension (PIH), glucose intolerance and anaemia are common
medical complications observed during pregnancy in Indian women and their effects were studied on the composition of colostrum
collected within 24 hours of delivery from lactating women included in the study. PIH during pregnancy significantly decreased
colostrum IgA and total proteins, but showed a significant increase in K+ levels, where as women with glucose intolerance showed a significant decrease in total lipids and lactose and an increase
in Na+ levels in colostrum compared to normal controls. The group with anaemia also showed a significant decrease in colostrum IgA
and total protein levels when compared with the control group. Awareness about the changes that occur in the composition of
colostrum during complicated pregnancies can be an important and useful tool for preventive and protective paediatrics. |
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| Keywords: | Colostrum composition Lactation Pregnancy Lipids Proteins |
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