Lipid peroxidation and antioxidant vitamins in urolithasis |
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| Authors: | J Kato Alice Abraham Ruram S Sekharjit Singh S Bilasini Devi Th Ibetombi Devi W Gyaneshwar Singh |
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| Institution: | (1) Department of Urology, Regional Institute of Medical Sciences, Imphal, Manipur;(2) Department of Biochemistry, Regional Institute of Medical Sciences, Pin-795004 Imphal, Manipur |
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| Abstract: | The present, study was conducted to determine the level of malondialdehyde (MDA) as an index of free radial induced lipid
peroxidation and antioxidant vitamins-vitamins A, vitamin C and vitamin E in 75 confirmed cases of urolithiasis. Significantly
high level of MDA (p<0.001) with significantly low levels of vitamin E (p<0.001) and vitamin A (p<0.001) with no significant
decrease in vitamin C (p>0.05) were observed in the plasma of urolithiasis cases as compared to normal controls. In conclusion,
it appears that a role of lipid peroxidation and oxidative function exists in the pathogenesis of urolithiasis. But, the exact
mechanism how this occurs remains to be elucidated. |
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| Keywords: | Lipid peroxidation Malondialdehyde (MDA) Antioxidant Vitamins Urolithiasis |
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