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Role of Heme Oxygenase, Leptin, Coenzyme Q10 and Trace Elements in Pre-eclamptic Women |
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| Authors: | Dina M Abo-Elmatty Ehsan A Badawy Jihan S Hussein Somaya Abo Elela Hoda A Megahed |
| Institution: | 1. Department of Biochemistry, Faculty of Pharmacy, Suez Canal University, Ismailia, 41522, Egypt 2. Department of Medical Biochemistry, National Research Center, Doki, Giza, Egypt 3. Department of Obstetrics and Gynecology, Faculty of Medicine, Cairo University, Cairo, Egypt |
| Abstract: | The objective of this study to evaluate heme oxygenase (COHb), leptin and coenzyme Q10 (CoQ10) in pre-eclamptic women. Also Zinc, copper, Iron, total iron binding capacity, Ferritin and uric acid were assessed. 120 female subjects were included in this study. They were divided into, 60 female with normal pregnancy attending the outpatient clinic, 60 pre-eclamptic patients were recruited from obstetrics and gynaecology department El-kasr El-Aini hospital. The results showed that in pre-eclampatic group, leptin level was significantly increased while COHb and CoQ10 was significantly decreased. It is concluded that hemeoxygenase, leptin and coenzyme CoQ10 can be considered as new markers for prediction of pre-eclampsia. |
| Keywords: | Pre-eclampsia Hemeoxygenase Carbon monoxide Leptin Coenzyme Q10 |
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