Serum and platelet sialic acid in acute myocardial infarction |
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| Authors: | P K Nigam V S Narain Naveen Chandra V K Puri R K Saran S K Dwivedi M Hasan |
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| Institution: | 1. Department of Cardiology, King George's Medical College, 226 003, Lucknow
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| Abstract: | Blood samples from 39 patients with acute myocardial infarction and 15 healthy controls were analysed for serum and platelet sialic acid. Serum sialic acid levels in patients with acute myocardial infarction were significantly higher than controls (mean 2.7±0.46 μmol/ml Vs. 1.91±0.17 μmol/ml respectively). Levels of serum orosomucoid, an acute phase reactant, containing sialic acid, were also higher in these patients, suggesting a possible non-specific mechanism of increase in serum sialic acid concentration. In contrast, platelets contained significantly less sialic acid in patients with acute myocardial infarction than control (26.73±1.57 nmol/mg protein and 31.97±2.68 nmol/mg protein respectively). |
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