Serum oestradiol in women with carcinomas of the breast and uterine cervix |
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| Authors: | Amitabha Ray Anil Kumar Bahadur S L Dayalu Naik Bhuvnesh Kumar Sharma |
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| Institution: | (1) Institute of Cytology and Preventive Oncology (ICMR), Maulana Azad Medical College, 110002 New Delhi;(2) Department of Radiotherapy, Maulana Azad Medical College, 110002 New Delhi |
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| Abstract: | Endogenous oestrogens are thought to be involved in breast cancer, but few studies could show the direct relationship between
hormones and pathological process of the disease. In the present study, oestradiol was estimated in the serum of pre-and postmenopausal
breast cancer patients along with normal healthy controls and patients with carcinoma of the uterine cervix which is not dependent
on oestrogens. Premenopausal patients with breast cancer showed higher levels of oestradiol as compared to premenopausal control
women as well as cervical cancer patients. Whereas, no statistically significant differences were observed in serum oestradiol
levels amongst postmenopausal groups of breast cancer, cervical cancer and normal women. The result of the study reflects
the association of oestradiol as well as its difference in the pathological events of pre and postmenopausal breast cancer. |
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| Keywords: | Oestradiol menopausal status breast cancer cervical cancer |
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