共查询到17条相似文献，搜索用时 140 毫秒
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近年来,生物传感器已广泛应用于基础研究、生物组分检测、临床疾病诊断、过程控制与检测、环境监控与保护等许多领域,电化学生物传感器是其中一个重要分支.纳米材料的尺寸小、比表面积大、表面原子配位不足、活性位点多等特性为生物传感器研究提供了新的途径,其迅猛发展对新型生物传感器的研制具有重要应用价值和意义.本文着重探讨了纳米材料在构建新型电化学生物传感器中的应用研究. 相似文献
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SPR生物传感器已广泛应用于易变反应物与传感器表面固定结合配体之间特定定性与定量分析.文章综述了这种新技术的研究和应用进展情况,传感器的组成和工作原理,传感器表面和固定,应用于实验的步骤,实验结果与未来发展趋势. 相似文献
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吴勇 《廊坊师范学院学报(自然科学版)》2010,10(6)
在酶传感器的制备工艺中,生物酶的固化及其催化反应的过程决定了酶传感器的灵敏性、选择性以及使用寿命,是整个工艺过程最为关键的环节.文章以生物酶的固化及催化过程作为研究重点,将壳聚糖、碳纳米管以及纳米金等材料应用于酶传感器的制备过程,利用壳聚糖的生物兼容性、多羟基结构以及其他纳米材料的物理特性,有效提高了葡萄糖生物传感器的灵敏性和使用寿命. 相似文献
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近年来,金属纳米颗粒的制备研究引起了人们的广泛兴趣.与相应的块体材料相比,金属纳米颗粒具有独特的化学和物理性质,可应用于电学、催化、磁性材料、光催化、生物染色剂、药物输送等许多领域.其中,传感器是纳米颗粒最有前途的应用领域之一.传感器的微型化是传感器发展的主要研究方向,将纳米颗粒用于传感器的研究将促进这一目标的实现.本论文利用纳米颗粒材料的独特效应来提高葡萄糖传感器的响应电流.将自制的银-金、铂以及二氧化硅和铂复合纳米颗粒用于固定化酶,使酶电极的电流响应值得到了大幅度的提高,从而为纳米增强的新型葡萄糖生物传感器的研究、制备和应用提供了可供参考的实验和理论依据,并为传感器的小型化开辟了一条新途径.论文的主要结果如下:
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本文研究了使用酸度、成膜时间以及BLM形成液的使用寿命对铂基质十六烷基三辛基碘化扶修饰BLM碘离子传感器性能的影响．结果表明，在20±2℃环境温度下，该传感器膜的形成时间为4～5min；在pH为5．0～10．0酸度范围内对碘离子具有好的响应．以0．1mol／LNaCl为底液，其线性范围为10－6～10－2mol／L[I-]，响应斜率为57mV／pC，符合能斯特响应．BLM形成液在三个月内使用无明显变化． 相似文献
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生物传感器由信号转换器件、生物敏感元件和检测电路组成,是敏感电子学的重要研究方向,属国际前沿技术。自1967年S.J.Updike等研制出了第一个葡萄糖生物传感器以来,生物传感器技术一直在不断向前发展。如今,随着电子信息科技与生物技术、微机电系统技术及纳米技术等高新技术的交叉融合,生物传感器向小型便携、实时快速、高灵敏、多参数和低成本方向发展,在临床卫生、食品安全、反恐侦查以及科学研究等方面具有重要应用需求, 相似文献
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生物传感器的应用和发展趋势 总被引：5，自引：0，他引：5
生物传感器以其高灵敏度和高选择性备受分析工作者的青睐.生物传感器在生物医学、环境监测、食品、医药及军事医学领域有重要应用价值,人们正致力于对它的研究与开发. 相似文献
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Ａ部分提示 :以下每个问题或未完成的句子都给出了五个建设性的答案或完成了该句子 ,从中选出一个最合适的 ,填在答题纸的相应处。1.下列哪项准确地阐明了细胞学说的原理 ?Ⅰ .所有生物都由细胞组成。Ⅱ .所有细胞都起源于原先已存在 (ｐｒｅｅｘｉｓｔｉｎｇ)的细胞。Ⅲ .细胞是生物学功能的基本单位。Ａ .仅Ⅰ Ｂ .仅Ⅱ Ｃ .仅Ⅰ和ⅡＤ .仅Ⅱ和Ⅲ Ｅ .Ⅰ ,Ⅱ ,和Ⅲ2 .原生质膜是半透性膜 ,它是主要由组成的细胞器。Ａ .类脂和糖 Ｂ .糖和蛋白质Ｃ .蛋白质和类脂 Ｄ .类脂和碳水化合物Ｅ .碳水化合物和蛋白质3 .厌氧呼吸过程会… 相似文献
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采用先分类后综合的方法对国内手机传感器应用于中学化学实验的14篇文献进行了研究.研究表明手机传感器中光线、图像、声音和气压传感器在中学化学实验中应用较多,手机传感器在溶液浓度测定中应用最多,在特征光谱测定、气体压强测定等也有较好的应用. 相似文献
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Milagros Castillo-Montoya Joshua Abreu Abdul Abad 《International journal of qualitative studies in education》2019,32(9):1125-1145
AbstractIn this study, we sought to understand how Black lives matter (BLM) epistemology, as displayed through six months of social media content from official accounts, can inform a racially liberatory pedagogy in higher education for Black and other racially minoritized students. We found BLM, through Facebook and Twitter, situated intersectional Black culture in the contemporary struggle for liberation. BLM also offered information that can raise its followers’ intersectional critical consciousness. Additionally, BLM content highlighted actions that can support Black liberation. Lastly, BLM content supported the building of relationships and naming of emotions as Black people work toward their liberation. In this sense, BLM connected with elements of a racially liberatory pedagogy and offered nuances that advanced the framework. We discuss the implications of this framework for teaching in higher education. 相似文献
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生物传感器研究进展及应用 总被引：2，自引：0，他引：2
彭友元 《泉州师范学院学报》2000,18(6):24-27,31
生物传感器从本世纪60年代诞生发展至今,在基础研究、应用研究、新产品开发和商品化等各方面都取得了惊人的进展。简述近年来生物传感器的研究进展。 相似文献
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Meseret F. Hailu Molly Sarubbi 《International journal of qualitative studies in education》2019,32(9):1108-1124
AbstractPopular media shapes societal perceptions and discourse. The growing use of news media in higher education practices (outreach, admissions, and campus communication) have heightened the need for institutional leadership to not only understand the general impact of popular media but also to comprehend students’ representation, as well as the acquisition and dissemination of media content. In this study, authors present a media content analysis of newspaper coverage of the Black Lives Matter (BLM) movement in the well-known periodical, the Chronicle of Higher Education. Ultimately, this study demonstrates (1) organizational leadership can be influenced and disrupted to promote racial justice and (2) the discursive treatment of the BLM in popular media and, and by extension, in the United States’ public imagination. Overall, this study suggests that in situations where institutional policies perpetuate racial inequity, BLM student movements have the capacity to complicate existing discourse about Blackness in higher education and catalyze substantial social change. 相似文献
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Objective: To investigate the evolution of pulmonary hypertension, the pathological changes of pulmonaryarteries, and the expression of VEGFmRNA and eNOSmRNA of pulmonary arterial endothelial cells in immature rabbitstreated with intratracheal bleomycin (BLM). Methods: Immature rabbits were divided into control and BLM group. Twoand four weeks after intratracheal normal saline or BLM injection, the systolic, diastolic and mean pulmonary arterypressure (PASP, PADP, MPAP) were measured by micro-catheter; the pathological changes and the expression ofVEGFmRNA and eNOSmRNA of endothelial cells in pulmonary arteries were evaluated by HE and in situ hybridization.Results: Two and four weeks after intratracheal injection of BLM, the PASP, PADP and MPAP increased 53%, 49%, 52%in 2 weeks, and 43%, 89%, 56% in 4 weeks; the wall thickness increased and the cavity in middle and small pulmonaryarteries became narrow; the Thickness Index (TI) and Area Index (AI) increased 25%, 14% in 2 weeks, and 22%, 24% in 4weeks; the level of VEGFmRNA and eNOSmRNA expression decreased 46%, 43% in 2 weeks, and 43%, 51% in 4 weeks.There was no significant difference between 2 weeks and 4 weeks BLM groups. Conclusion: The pulmonary artery pressurewas elevated, the thickness of wall increased and the cavity became narrow in middle and small pulmonary arteries, and thelevel of VEGFmRNA and eNOSmRNA expression in pulmonary arterial endothelial cells decreased in immature rabbitsafter 2 weeks and 4 weeks of intratracheal 4 U/kg BLM injection. 相似文献
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INTRODUCTION Pulmonary hypertension is not rare in humanwith some heart and lung diseases. Chronic pul-monary hypertension leads to structural alterationsof the lung vessels. The pathophysiology of thisremodeling process is still poorly understood.Furthermore, the structural damage of the lungvessels limits the clinical success of vasodilatortreatment. Assuming genetic susceptibility, shearstress and inflammation are the principal pathoge-netic factors involved in lung vessel remode… 相似文献
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Chun-sheng Wu Pei-hua Chen Qing Yuan Ping Wang 《Journal of Zhejiang University. Science. B》2009,10(4):285-290
This paper presents a novel strategy for the response enhancement of olfactory sensory neurons (OSNs)-based bio-sensors by monitoring the enhancive responses of OSNs to odorants. An OSNs-based biosensor was developed on the basis of the light addressable potentiometric sensor (LAPS), in which rat OSNs were cultured on the surface of LAPS chip and served as sensing elements. LY294002, the specific inhibitor ofphosphatidylinositol 3-kinase (PI3K), was used to enhance the responses of OSNs to odorants. The responses of OSNs to odorants with and without the treatment of LY294002 were recorded by LAPS. The results show that the enhancive effect of LY294002 was recorded efficiently by LAPS and the responses of this OSNs-LAPS hybrid biosensor were enhanced by LY294002 by about 1.5-fold. We conclude that this method can enhance the responses of OSNs-LAPS hybrid biosensors, which may provide a novel strategy for the bioelectrical signal monitor of OSNs in biosensors. It is also suggested that this strategy may be applicable to other kinds of OSNs-based biosensors for cellular activity detection, such as microelectrode array (MEA) and field effect transistor (FET). 相似文献