共查询到11条相似文献，搜索用时 875 毫秒
1.
磷酸铝分子筛拥有规则的多孔结构,具有吸附、储存甲烷的能力,以前的研究报道多侧重于它们储存量的研究而对它们结构与吸附量关系的研究报道很少。实验研究了磷酸铝分子筛AlPO-53,SAPO-34和AlPO-5在温度273 K和303 K、压力100-2000kPa条件下的甲烷储存性质并讨论它们的储甲烷量与其结构之间的关系。在实验条件下,具有笼形结构的SAPO-34（0.38×0.38 nm）具有最大的甲烷储存量（2.35mmol/g,273 K,2000 kPa）,而具有笼形结构的AlPO-53（0.31×0.43 nm）和具有直孔型孔道的AlPO-5（0.73×0.73 nm）的甲烷储存量相当（1.54 mmol/g,273 K,2000 kPa）,均低于SAPO-34分子筛。结果表明,分子筛的笼型结构对其甲烷的储存量至关重要,具有最佳吸附孔径的微孔吸附剂,只有具有了笼型结构才可能具有好的甲烷储存能力;孔口小于甲烷动力学直径的有笼型结构的微孔吸附剂也能具有较大的甲烷储存能力。 相似文献
2.
《普罗米修斯》2012,30(1):63-82
Nowadays the governments of industrialised countries, in the presence of reduced public resources, have to assign clear objectives to public research laboratories to increase the competitiveness of firms. The purpose of this article is to analyse the public research bodies of the National Research Council of Italy in order to pinpoint the main typologies operating in the national system of innovation (NSI). This research shows four main types of research institutes as drivers of NSI. The results can supply useful information to policy makers on the behaviour of these structures and on their strengths and weaknesses. 相似文献
3.
《中国科学院院刊(英文版)》2021,(1)
正On the night of February 10,a time when the Chinese people are awaiting the advent of the Year of the Ox,Tianwen-1,the first Mars probe of China,brakes and slows down to enter the Red Planet’s gravity field safe and sound.Days ago,it just hit headlines once again by sending back the first photo of Mars it shot when approaching the destination, 相似文献
4.
Suvidya H. Ranade Ashraf Hossani D. N. Deobagkar D. D. Deobagkar B. A. Chopade Pramod S. Khandekar 《Indian journal of clinical biochemistry : IJCB》2009,24(2):142-149
We report complete sequences of 2 genes of S.flexneri 1a an Indian isolate for the first time. Shigella is causative agent
of shigellosis or bacillary dysentery. Genomic library was constructed by shotgun approach. Sequencing was carried out using
Big Dye terminator chemistry using ABI 3730 48 capillary DNA analyzer. 170 recombinants were subjected to nucleotide sequencing.
Sequence data was analyzed, of these 2 clones showed presence of complete genes out of the total clones sequenced. Annotations
were done using various bioinformatics tools. Gene Sfo676 on contig SF21B11, 513 bp long codes for a protein 170 aa long with
molecular weight of 18836.5 daltons. The protein is 99 % identical to S. flexneri 2a 301 and not with any other strain of
Shigella. It has 7 different sites for phosphorylation, myristoylation and glycosylation. Predicted cellular localization
is cytoplasmic membrane. SF0368 is another full-length gene SF0368 on contig SF69C1 is a 312 nucleotide long. It is 103 aa
long with molecular weight 11394.0 daltons. Protein is 100% identical to S. flexneri 2a 301 and 99% with S. sonnei strain
046. The gene shows difference when compared with S.sonnei in mono and dinucleotide frequency as well as amino acid composition. 相似文献
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6.
Xue Wang Yuetong Wang Zhaoyuan Fang Hua Wang Jian Zhang Longfu Zhang Hsinyi Huang Zhonglin Jiang Yujuan Jin Xiangkun Han Shenda Hou Bin Zhou Feilong Meng Luonan Chen Kwok-Kin Wong Jinfeng Liu Zhiqi Zhang Xin Zhang Haiquan Chen Yihua Sun Liang Hu Hongbin Ji 《国家科学评论(英文版)》2021,8(10)
Somatic mutations of the chromatin remodeling gene ARID2 are observed in ∼7% of human lung adenocarcinomas (LUADs). However, the role of ARID2 in the pathogenesis of LUADs remains largely unknown. Here we find that ARID2 expression is decreased during the malignant progression of both human and mice LUADs. Using two KrasG12D-based genetically engineered murine models, we demonstrate that ARID2 knockout significantly promotes lung cancer malignant progression and shortens overall survival. Consistently, ARID2 knockdown significantly promotes cell proliferation in human and mice lung cancer cells. Through integrative analyses of ChIP-Seq and RNA-Seq data, we find that Hspa1a is up-regulated by Arid2 loss. Knockdown of Hspa1a specifically inhibits malignant progression of Arid2-deficient but not Arid2-wt lung cancers in both cell lines as well as animal models. Treatment with an HSPA1A inhibitor could significantly inhibit the malignant progression of lung cancer with ARID2 deficiency. Together, our findings establish ARID2 as an important tumor suppressor in LUADs with novel mechanistic insights, and further identify HSPA1A as a potential therapeutic target in ARID2-deficient LUADs. 相似文献
7.
Sadegh Fattahi Mohammad Karimi Alivije Farhang Babamahmoodi Masomeh Bayani Mahmoud Sadeghi Haddad Zavareh Mohsen Asouri Maryam Lotfi Galia Amirbozorgi Haleh Akhavan-Niaki 《Indian journal of clinical biochemistry : IJCB》2018,33(4):467-472
Hepatitis B virus (HBV) infection is a worldwide health concern which is associated with significant morbidity and mortality. Both viral and host factors have a significant effect on infection, replication and pathogenesis of HBV. The aim of this study was to investigate the effect of CYP2E1 and CYP1A1 genetic variants on susceptibility to HBV. 143 individuals including 54 chronic HBV patients and 89 healthy controls were enrolled in the genotyping procedure. rs2031920 and rs3813867 at CYP2E1 as well as rs4646421 and rs2198843 at CYP1A1 loci were studied in all subjects using PCR–RFLP (restriction fragment length polymorphism) analysis. Both variants at CYP2E1 locus were monomorphic in all studied subjects. Genotype frequency of rs4646421 was significantly different between chronic HBV patients and healthy blood donors (P = 0.04, OR 4.31; 95% CI 1.04–17.7). Furthermore, individuals carrying at least one C allele (CC or CT genotypes) for rs4646421 seemed to have a decrease risk of hepatitis in comparison with TT genotype (P = 0.039). Our results showed a relationship between rs4646421 TT genotype (rare genotype) and the risk for developing chronic HBV infection (four times higher). Further studies are needed to examine the role of CYP1A1 polymorphism in susceptibility to chronic HBV infection. 相似文献
8.
现代CMOS工艺的发展使得在CMOS工艺上设计射频IC前端成为可能。但在传统CMOS工艺集成的片上螺旋电感品质因数(Q)偏低,大大影响其性能。通过引入负电导实现螺旋电感Q值提升,并将其应用于共栅低噪声放大器的设计。 相似文献
9.
Raymond Kolcaba 《Ethics and Information Technology》2000,2(1):3-9
Humanity has begun to move from the natural world intothe cyber world. Issues surrounding this mentalmigration are debated in philosophical dialogue. Thelead character is Becket Geist, a romantic philosopherwith views tempered by 20th century science. He openswith a monologue in which he argues that loss of theworld in exchange for the cyber world is dark andinevitable. His chief adversary is Fortran McCyborg,a cyborg with leanings toward Scottish philosophy. The moderating force is Nonette Naturski who championsnaturalism, conservation of humanist ideals, andprudent conclusions. The ensuing dialogue examineseight counter-arguments to Geist's vision. Thearguments and Geist's replies lead to unanticipatedchanges in position that cascade to a chillingclose. 相似文献
10.
江泽民同志的“七一”讲话以高度的创造精神和理论勇气，坚持用邓小平理论观察世界和中国，善于科学总结党和人民八十年革命、建设和改革实践中创造的新经验，大胆进行了一系列理论创新：提出新问题；阐述新论点；设计新方案；揭示新规律。这不仅为理论工作者树立了丰富和发展马克思主义、进行理论创新的典范，也将指导党和人民创造出无愧于时代的伟大业绩。提出新问题创造学认为，问题是创造之母，创造之始，创造之源。提出问题是创造过程的第一阶段，也是理论创新的第一步。恩格斯早在１８７８年出版的《反杜林论》“引论”中就强调过提出… 相似文献
11.
Chatterjee S Dhar S Sengupta B Ghosh A De M Roy S Chakrabarti S 《Indian journal of clinical biochemistry : IJCB》2010,25(3):260-272
Polycyclic aromatic hydrocarbons of tobacco require activation by phase I enzymes, such as cytochrome-P4501A1 (CYP1A1) to
become an ultimate carcinogen, which are subjected to detoxification by phase II enzymes, especially glutathione S-transferases (GSTs). A study was designed to find whether genetic predisposition are risk modifiers of oral pathologies.
The study included 102 cases with Oral Cancers (OCs), 68 cases with nonmalignant pathologies, 100 cases as control group.
GSTM1 null genotype was associated with increased risk of OCs but not with benign pathologies. Deleted GSTT1 was associated
with all pathologies. Both m1m2 and m2m2 polymorphisms of CYP1A1 were associated with oral pathologies. 相似文献