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1.
目的 :观察奥美拉唑联合阿莫西林和呋喃唑酮治疗幽门螺杆菌感染的效果 .方法 :将2 4 0病例随机分为两组 .治疗组采用奥美拉唑联合阿莫西林和呋喃唑酮 (简称奥组 ) ,对照组采用果胶铋联合阿莫西林和甲硝唑 ,疗程两周 .结果 :治疗组和对照组HP根除率分别为96 7%和 6 8 3% ,溃疡及糜烂面愈合率分别为 90 0 %和 6 1 7% ,两组差异有显著性意义 (P <0 0 1) .结论 :奥美拉唑联合阿莫西林和呋喃唑酮是目前一种理想的根除HP治愈溃疡及糜烂面的方案 . 相似文献
2.
目的 :观察枸橼酸铋钾联合克拉霉素和替硝唑根除幽门螺旋杆菌 (HP)感染的疗效。方法 :将12 2例幽门螺旋杆菌阳性的消化性溃疡病人随机分为两组 :治疗组用枸橼酸铋钾联合克拉霉素和替硝唑短程治疗一周 ;对照组用奥美拉唑联合头孢羟氨苄和甲硝唑治疗二周。结果 :治疗组和对照组的HP根除率分别为 83 9%和 85 % ,溃疡愈合率分别为 85 5 %和 88 3% (p >0 0 5 )。结论 :枸橼酸铋钾联合克拉霉素和替硝唑能有效根除HP ,促进溃疡愈合 ,且不良反应少 ,疗程短 ,经费低 ,病人顺从性好 ,值得推广 相似文献
3.
目的：探讨微生态制剂联合兰索拉唑、克拉霉素片、阿莫西林胶囊在幽门螺杆菌感染治疗中的疗效及安全性。方法：将118例慢性胃炎或消化性溃疡且经快速尿素酶试验、病理切片染色镜检、13C-尿素酶呼气试验检测幽门螺杆菌任何两项阳性患者随机分为联合治疗组60例,常规三联方根除治疗（兰索拉唑＋克拉霉素＋阿莫西林胶囊）加0．35g双歧杆菌片0．7g2次／d,口服,与抗菌药物间隔2h服用,疗程14d。对照组58例,常规三联方根除治疗（兰索拉唑＋克拉霉素＋阿莫西林胶囊）不使用双歧杆菌,疗程14d。治疗结束4周后复查”C－尿素酶呼气试验。比较两组根除率及不良反应发生率。结果：联合治疗组根除率80％,对照组根除率77．5％,两组间差异无统计学意义（P〉．05）,但是联合治疗组不良反应发生率6．7％与对照组不良反应发生率22．4％比较差异具有统计学意义（P〈0．05）。结论：常规三联疗法结合双歧杆菌片在幽门螺杆菌感染治疗中不良作用少,患者依从性较好,值得临床推广和应用。 相似文献
4.
本文选择肺性脑病并高粘血症42例分为两组,一组为治疗组(抗栓酶-3号加常规治疗)21例。用抗栓酶-3号1.0单位加入生理盐水250ml静滴,每日一次。二组为对照组(常规治疗)21例,每日一次。疗程均为2周。治疗前后均测定血小板集聚率、全血粘度、红细胞压积。结果治疗组总有效率90.5％,对照组57.4％,两组相差显著,前者明显优于后者。 相似文献
5.
杨振玉 《河北北方学院学报(医学版)》1997,(3)
慢性肾功能不全18例。分为中西药治疗组13例,每日早餐前服洛丁新10mg一次,肾灵胶囊2片,每日3次,速尿40mg,每日1次;中药用东昂降脂灵5片。每日口服3次;乐脉颗粒3克,每日口服3次。西药治疗组每日早餐前服洛丁新10mg。每日1次,潘生丁50mg每日3次,肾灵胶囊2片,每日3次,速尿40mg,每日1次,各组疗程均为8周。与服药前比较中西药治疗组BUN下降69.6％;cre下降50％,SG升高10.9％。尿蛋白全部转阴。CHO下降68％;IG下降61.9％;HDL升高34.6％,P均<0.001。西药治疗组BUN下降18.2％,cre下降14.33％;SG升高6％;GT下降3.7％;CHO下降2.7％;P均>0.05。两组相比各值均有非常显著的统计学差别P均<0.001。中西医治疗组疗程结束时无不良反应及副作用发生。本试验显示中西药治疗组有满意的疗效。 相似文献
6.
目的:观察红强二甲基亚砜搽剂治疗慢性湿疹的临床疗效及安全性。方法:治疗组60例外用红强二甲基亚砜搽剂,对照组60例外用舒肤特搽剂,每天2次,疗程3周。于疗程结束后记录疗效及副作用。结果:治疗组总有效率为90%,对照组总有效率为75%,经统计学处理有显著性差异,两组局部刺激反应发生率无显著性差异,但复发率有显著性差异。结论:红强二甲基亚砜治疗慢性湿疹比舒肤特更为有效。 相似文献
7.
刘彩凤 《雁北师范学院学报》2013,(1):58-59,84
目的探讨以四联疗法作为一线方案治疗幽门螺旋杆菌（HP）阳性的胃病患者临床疗效,并与传统三联疗法比较,找出更有效的根治HP的办法。方法将105例HP阳性患者随机分为2组,对照组48例患者给予传统三联疗法,而治疗组57例患者给予含铋剂的四联疗法,治疗结束后4周复查2组患者的HP感染。结果对照组HP根治率为77.08%,治疗组为92.98%,两组结果经统计学检验有显著性差异（P〈0.05）。两组的副反应无显著性差异（P〉0.05）。结论四联疗法根治幽门螺杆菌感染较三联疗法疗效更显著,且副作用小,费用合理,可作为初治方案进一步推广。 相似文献
8.
氟西汀抗脑卒中后抑郁的观察 总被引：1，自引：0，他引：1
目的:观察氟西汀抗脑卒中后抑郁对神经功能缺损的影响.方法:140例患者随机分为2组.治疗组80例,入院后即给予氟西汀0.4mg口服,晚1次,6～10周为1个疗程.对照组60例,入院后口服多虑平25mg,每日1次,其余治疗两组均按脑卒中常规处理.在治疗1周、2周、4周、6周后分别以HAMD量表及ESS量表评定治疗效果.结果:治疗组用药后1周即可显效,而对照组多在2周后显效.两组ESS评分均随HAMD评分下降而下降,两者呈正相关,而治疗组ESS评分较对照组下降明显,有显著性差异(P＜0.01).结论:氟西汀抗脑卒中后抑郁能够改善神经功能缺损症状及患者的预后. 相似文献
9.
为了探讨肠易激综合征(IBS)及其亚型与幽门螺杆菌(HP)感染的关系,本研究随机选取120例IBS患者为实验组,120例健康体检者为对照组,通过14C尿素呼气试验及快速尿素酶法,分析肠易激综合征及各亚型患者的幽门螺杆菌感染情况并将HP阳性的IBS患者各亚型随机分为观察组与对照组,两组同时给予匹维溴铵、蒙脱石治疗4周,观察组加用HP药物治疗2周,观察其疗效。结果表明,实验组(IBS组)HP阳性率60.8%(73/120)高于对照组(健康体检者)45%(54/120),差异有统计学意义;IBS各亚型患者HP感染率分别为:便秘型47.3%(9/19)、腹泻型75%(12/16)、混合型75%(12/16)、未定型58%(40/69),差异有统计学意义;HP阳性IBS各亚型患者:腹泻型观察组治疗总有效率(83.3%),明显高于对照组(33.3%),差异有统计学意义(P<0.05),便秘型观察组治疗总有效率(50%),明显高于对照组(20%),差异有统计学意义(P<0.05),混合型观察组治疗总有效率(83.3%),明显高于对照组(33.3%),差异有统计学意义(P<0.05),未定型观察组治疗总有效率(80%),明显高于对照组(45%),差异有统计学意义(P<0.05)。这说明HP感染与肠易激综合征之间有一定关系,根除HP可能在IBS治疗中起一定作用。 相似文献
10.
甲氨蝶呤联合益赛普治疗类风湿风湿关节炎 总被引：1，自引：0，他引：1
目的评价甲氨蝶呤联合益赛普治疗类风湿关节炎（RA）临床疗效以及安全性.方法随机将90例类风湿关节炎患者分为2组：联合治疗组45例,口服甲氨蝶呤10～15 mg 1次/周,益赛普50 mg 1次/周,皮下注射;对照组45例单用甲氨蝶呤10～15mg 1次/周.疗程为3月,对2组的临床症状及实验室指标改善情况进行评价.结果2组的临床症状即关节疼痛数、关节肿胀数的改善均有良好效果,联合治疗组优于对照组;2组治疗后血沉（ESR）、C反应蛋白（CRP）均明显降低,且联合治疗组优于对照组.安全性方面,联合用药组一例出现肺部感染,停药及给予消炎药后好转.1例最初出现注射局部皮肤红肿伴瘙痒,3d后自行消失,未影响患者正常用药.对照组1例于服用甲氨蝶呤第2日出现头晕及胃肠道不适,1例出现口腔溃疡,1例化验血常规白细胞降低.结论甲氨蝶呤联合益赛普治疗类风湿关节炎疗效肯定,不良反应少,且明显较单用甲氨蝶呤组效果好. 相似文献
11.
在封闭式流动水体中,对昆明裂腹鱼鱼苗的耗氧率和临界窒息点进行初步测定。试验结果表明:在常温(20℃)条件下,临界窒息点为0.8mg/L(L:12.5cm-16.4cm,W:15.32g-34.28g)。而耗氧率的测定结果则为:在常温20℃:昼夜平均耗氧率为0.215mg/g.h(L:13.5-15.5cm,W:19.75-31.31g),昼夜耗氧率差异不明显;在17.5℃时,昼夜平均耗氧率为0.13 mg/g.h(L:11.9-15.1cm,W:15.16-27.74g),昼夜耗氧率差异明显;在15℃时,昼夜平均耗氧率为0.10 mg/g.h(L:12.6-14.5cm,W:15.66-25.35g),昼夜耗氧率差异明显,昆明裂腹鱼的耗氧率随温度的降低而减小。 相似文献
12.
大蒜素对肉鸡生产性能和消化酶活性的影响 总被引：1，自引：0，他引：1
135只1日龄AA鸡随机分成A、B、C3组,每组设3个重复,每个重复15只。A为空白对照组,饲喂基础日粮,B为抗生素组,在基础日粮中添加50mg／kg洛克沙生和750mg／kg10％金霉素,C为试验组,在基础日粮中添加160mg／kg25％大蒜素,以研究大蒜素对肉鸡生产性能和十二指肠消化酶活性的影响。试验结果表明,A、B、C3组肉鸡平均体重和平均日增重差异不显著（P〉0．05）,与A组相比,42日龄时C组料重比差异显著（P〈0．05）。在21日龄和42日龄时,C组淀粉酶活性较A组提高了122．87％（P〈0．01）和40．50％（P〈0．01）,脂肪酶活性较A组提高了89．98％（P〉0．05）和33．33％（P〉0．05）,总蛋白酶活性较A组提高了10．29％％（P〉0．05）和1．7％（／9〉0．05）。本结果提示在肉鸡饲料中添加大蒜素能够提高饲料效率和肠道淀粉酶活性。 相似文献
13.
目的：观察奥扎格雷钠与黄芪注射液联合治疗糖尿病肾病的疗效。方法：将84例早期糖尿病肾病患者随机分为3组，每组28例，在常规治疗的基础上，A组加用黄芪注射液，B组加用奥扎格雷钠注射液，C组加用黄芪注射液与奥扎格雷钠注射液，疗程均为20d。观察治疗前后各组尿白蛋白排泄率（UAER），血尿素氮（BUN），血清肌酐（SCr），糖化血红蛋白（HbAlc）的变化。结果：糖化血红蛋白，血清肌酐，血尿素氮，尿白蛋白排泄取：3组治疗后均比治疗前显著下降（P〈0．01），C组下降幅度优于A组和B组（P〈0．05）。结论：奥扎格雷钠联合黄芪注射液治疗糖尿病肾病能降低糖化血红蛋白，显著降低尿白蛋白排泄率，同时改善肾功能。 相似文献
14.
参芪扶正注射液对慢性肺心病患者血液流变学的影响 总被引：1，自引：0，他引：1
目的:观察参芪扶正注射液对慢性肺原性心脏病(以下简称肺心病)患者血液流变学的影响.方法:将74例慢性肺心病急性加重期患者随机分为A、B两组.A组(36例)在常规治疗的基础上加用参芪扶正注射液,B组(38例)仅给予常规治疗.两组均连续用药2周.治疗前后对血液流变学相关指标进行检测与对比观察.结果:患者经参芪注射液治疗后血液流变学示低切与高切变率下全血黏度、血浆比黏度、红细胞聚集指教、红细胞电泳时间、红细胞比积、血小板聚集率、纤维蛋白原均有显著性下降(P＜0.01或P＜0.05),与B组比较亦有显著下降(P＜0.05).临床总有效率及显效率A组分别为94.5%及50.0%;B组为73.6%及26.4%.A组疗效明显优于B组(P＜0.05),治疗期间未见参芪扶正注射液严重不良反应.结论:参芪扶正注射液能显著改善慢性肺心病急性加重期患者的血液流变性,是辅助治疗肺心病的一种有效、安全的药物. 相似文献
15.
为找出治疗禽流感的有效方法,将800只患有禽流感的病鸡随机分成A、B、C、D四组,每组200只.A组用中药“病毒清”饮水剂饮水(2m l只/,2次/日);B组用板兰根注射液治疗;C组用“金刚烷胺 安乃近”治疗;D组为空白对照组.试验结果表明:A组治疗率比B、C组分别高出11.5%和21.5%,比空白对照组高出29%.差异极显著(P<0.01).提示中草药“病毒清”防治禽流感效果显著. 相似文献
16.
Wen-hua RUAN Mei-li HUANG Xiao-lei HE Feng ZHANG Hai-biao TAO 《Journal of Zhejiang University. Science. B》2013,14(3):253-258
Objective:To evaluate the pharmacological effects of traditional Chinese medicine,bear bile capsule and Huangqi granule,on recurrent parotitis in children.Methods:In this prospective,controlled,and randomized study,a total of 151 young children were divided into three groups:Group A included massaging the children’s parotid region and melting vitamin C in their mouth daily;Group B included swallowing bear bile capsule and Huangqi granule daily;and Group C included massages and vitamin C as prescribed in Group A,and traditional Chinese medicine as prescribed in Group B.Children were treated individually for one month and then a follow-up study was conducted for 1 to 3.5 years.Analysis of variance(ANOVA) and Ridit analysis were employed for statistical analysis.Results:The recurrence rate decreased in every group,but was significantly more in Groups B and C when compared to Group A.The recurrences significantly decreased(P<0.01) in Group B and their recovery rate was as high as 63%,significantly better than those of the other groups(P<0.01).Conclusions:Huangqi and bear bile could be a novel clinical approach for treating recurrent parotitis in children. 相似文献
17.
Canbaz H Dirlik M Colak T Ocal K Akca T Bilgin O Tasdelen B Aydin S 《Journal of Zhejiang University. Science. B》2008,9(6):482-488
Objective: To investigate the effect of recurrent laryngeal nerve (RLN) identification on the complications after total thyroidectomy and lobectomy. Methods: Total 134 consecutive patients undergoing total thyroidectomy or thyroid lobectomy from January 2003 to November 2004 were investigated retrospectively. Patients were divided into two groups: RLN identified (Group A) or not (Group B). The two groups were compared for RLN injury and hypocalcaemia. Results: The numbers of patients and nerves at risk were 71 and 129 in Group A, and 63 and 121 in Group B, respectively. RLN injury in Group A (0) was significantly lower than that in Group B (5[7.9%]) patients, 7 [5.8%] nerves) for the numbers of patients (P=-0.016) and nerves at risk (P=0.006). Temporary hypocalcaemia was significantly higher in Group A than in Group B (14 [24.1%] vs 6 [10.3%], P=0.049).Permanent complications in Group B were significantly higher than those in Group A (13 [20.6%] vs 4 [5.6%], P=0.009). Conclusion: RLN injury was prevented and permanent complications were decreased by identifying the whole course and branches of the recurrent laryngeal nerve during total thyroidectomy. 相似文献
18.
Gao Min Zhou Wen Shi Jian-ming Hong De-fei Mu Yi-ping Wang Jian-guo Wang Yao-dong 《浙江大学学报(A卷英文版)》2000,1(4):456-458
Objective: To evaluate the benefit of intraoperative ERCP and endoscopic sphincterotomy (EST) combined with laparoscopic cholecystectomy
(LC) in the treatment of cholelithiasis with choledocholithiasis. Methods: Fifty-two patients with cholelithiasis and choledocholithiasis
(as determined by intraoperative cholangiography) were randomly divided into 2 groups during LC. In group A (27 patients),
common bile duct stones were extracted by intraoperative EST during LC. In group B(25 patients), common bile duct (CBD) stones
were extracted by conversion to open CBD exploration and cholecyctectomy. Results: The success rate was 26/27 (96.3%) in group
A and 25/25 (100%) in group B (0.25<P<0.5); The mean postoperative hospitalization was 3.32±0.56 days in group A and 17.5±4.61 days in group B (P<0.001). In group A, two cases were complicated transient hyperamylasemia after the combined procedure. In group B, one case
of bile leakage and one case of duodenal ulcer occurred after conversion to open cholecystectomy with CBD exploration. There
were no retained stones in group A but 2 cases in group B. Conclusion: Intraoperative ERCP and endoscopic sphincterotomy combined
with LC for treatment of cholelithiasis and chiledochlithiasis is safe, effective and results in shorter hospitalization and
fewer complications than traditional open cholecystectomy with CBD exploration. 相似文献
19.
Objective: To investigate if intra-aortic balloon pump(IABP) is contraindicated without anticoagulation therapy. Methods:
Some 153 IABP patients in the King Abdulaziz Cardiac Center(KSA) were randomly assigned into two groups. Anticoagulation group
(Group A) consisted of 71 patients who were given heparin intravenously with target aPTT50–70 seconds. Non-anticoagulation
group (Group B) consisted of 82 patients without intravenous heparin during balloon pumping. Hematological parameters including
platelet count, D-dimer, Plasminogen activator inhibitor-1 (PAI-1) and fibrinogen degradation products (FDP) were checked
respectively at the point of baseline, 24 hours, 48 hours and 24 hours post IABP counterpulsation. Clot deposits on balloon
surface, vascular complications from IABP including bleeding and limb ischemia were recorded. Results: Platelet count and
PAI-1 level decreased at 24 hours and 48 hours in both groups (P<0.05). D-dimer dimer and FDP level increased at 24 hours and 48 hours in both groups(P<0.05), but returned to the baseline level 24 hours post IABP removal (P>0.05). Three patients in Group A and 2 patients in Group B developed minor limb ischemia (P>0.05). No major limb ischemia in either group. Two patients in Group A suffered major bleeding and required blood transfusion
or surgical intervention, whereas no patient had major bleeding in Group B. Eight patients had minor bleeding in Group A,
but only 2 patients in Group B (P<0.05). No clot deposit developed on IABP surface in either group. Conclusion: IABP is safe without routine anticoagulation
therapy. Selecting appropriate artery approach and early detection intervention are key methods for preventing complications. 相似文献