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1.
目的：观察生大黄对急性胰腺炎的临床疗效.方法：将60例急性胰腺炎患者按照随机数字表方法分为对照组和观察组,对照组按照急性胰腺炎常规治疗方案治疗;观察组在常规治疗方案的基础上早期予以生大黄液经胃管注入及保留灌肠,观察两组患者腹痛缓解时间、血尿淀粉酶恢复时间,平均住院日等指标.结果：观察组的相关指标较对照组明显减低,具有统计学差异（P<0.05）,提示观察组优于对照组.结论：早期应用生大黄能够改善患者病情,缩短住院天数,具有较好的推广价值. 相似文献
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目的研究柴胡香薷饮治疗小儿夏季急性上呼吸道感染临床效果。方法:采用随急性上呼吸道感染患儿198例,随机分为柴胡香薷饮治疗组与对照组,对照组予小儿速效伤风冲剂,静滴利巴韦尔10m g/kg。治疗组113例,男71例,女42例,年龄11月～7岁,平均年龄3.6±5.2岁;病情轻度26例,中度12例,重度75例。对照组85例,男51例,女34例,年龄12个月～7岁,平均3.8±5.9岁;病情轻度13例,中度18例,重度54例。结果:体温变化:二组治疗前后6小时无显著性差异,轻中度患儿二种方案均有较好效果,但重度患儿中治疗后12、48、72小时有显著性差异(P<0.01)。对照组退热效果显著低于治疗组。症状积分变化:轻、中度患儿两组治后无显著性差异,重度患儿治疗后3天有显著性差异(P<0.01),表明柴胡香薷饮对缓解小儿夏季急性上感各症状优于对照组。综合疗效比较:轻、中度患儿治疗效果两组无显著性差异;重度患儿治疗组痊愈率高于对照组,无效率明显低于对照组,有显著性差异(P<0.01),表明柴胡香薷饮治疗夏季急性上感临床效果优于对照组。结论:柴胡香薷饮有较好退热、缓解症状的作用,治疗效果较单用西药好。 相似文献
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目的观察乌司他丁联合常规治疗方案治疗急性重症胰腺炎的效果及预后。方法回顾性对比分析急性重症胰腺炎常规治疗联合乌司他丁及单纯常规治疗各30例的治疗结果及预后。结果联合乌司他丁治疗组的腹部症状、体征、实验室各指标及肺功能恢复,和对比组比较有显著差异(P<0.05);在白细胞总数恢复时间上无明显差异,但有缩短趋势;ARDS发生率下降,总体病死率下降。结论联合乌司他丁治疗急性重症胰腺炎能更快地控制病情,抑制体内炎症反应,减少ARDS发生率,明显缩短病程。 相似文献
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分别对无偿自愿献血者的新鲜血浆及冷上清进行留样,并检测其中凝血因子FVIII、FIX、FV、FVII、Fbg及总蛋白含量.检测结果进行统计学分析（t检验）.冷上清中FVIII含量为（0.35±0.13）IU/mL;FIX含量为（0.61±0.15）IU/mL;FV含量为（0.93±0.18）IU/mL;FVII含量为（1.06±0.35）IU/mL;Fbg含量为（142.41±37.77）mg/dL;TP含量为（62.90±5.01）g/L.新鲜冰冻血浆中FVIII、FV、Fbg含量与冷上清中FVIII、FV、Fbg含量相比较,均为P〈0.01,有极显著差异.新鲜冰冻血浆中FIX、FVII、TP含量与冷上清中FIX、FVII、TP含量相比较,均为P〉0.05,无显著差异.结果表明,冷上清中含不稳定因子FV、FVIII,但其含量与新鲜冰冻血浆相比较低.用冷上清对TTP患者行血浆置换后,可使患者凝血系统恢复正常,病情明显好转. 相似文献
6.
目的:探讨保心汤对稳定型心绞痛患者血管内皮生长因子(VEGF)和心率变异性(heart rate variability,HRV)的影响.方法:82例冠心病稳定型心绞痛患者随机分为 2组,中药组服用常规西药加中药保心汤,常规组服用常规西药.治疗前和治疗 4周后分别检测 2组血浆 VEGF和24h动态心电图HRV的变化.结果:血浆 VEGF和 HRV治疗前 2组比较差异无显著性;治疗后中药组VEGF明显增加(P<0.05),常规组无明显变化;两组均能改善HRV,但中药组改善更加明显 (P<0.005).结论:保心汤能提高血浆VEGF和改善心率变异性,通过促进冠脉侧支循环的建立而达到治疗冠心病及改善预后的目的. 相似文献
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目的:评价中西医结合用中药协定方辅助治疗中重度支气管哮喘急性发作期的近期疗效。方法:将94例中重度支气管哮喘急性发作期患者随机分成中西医结合治疗组47例,对照组47例;两组性别、年龄、病情严重度分级及病程等相似。对照组用西医常规平喘及对症支持疗法治疗。中西医结合治疗组在西医常规治疗的基础上加用中药协定方水煎服,每日1剂,分两次服。两组均以10d为一疗程。结果:中西医结合治疗组患者的咳、痰、喘症状及肺部哮鸣音消失时间快于对照组,显效率及总有效率均高于对照组(P<0.01),而且无不良反应。结论:中西医结合用中药协定方辅助治疗中重度支气管哮喘急性发作期的疗效优于单纯西医常规治疗。 相似文献
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急性脑梗死患者血清中IL-1β及IL-6水平变化的研究 总被引：1，自引：0，他引：1
目的:研究急性脑梗死患者血清中IL-1β及IL-6含量的变化。方法:采用病例对照的研究方法,选择急性脑梗死患者45例为病例组,健康体检者40例为对照组,用酶联免疫吸附法定量检测血清中IL-1β及IL-6的含量。结果:病例组血清中IL-1β、及IL-6的含量平均值分别是24.8±5.1pg/ml和23.2±8.4pg/ml;对照组分别是15.0±4.6pg/ml和19.5±9.9,两组比较有统计学意义。结论:急性脑梗死患者血清中IL-1β及IL-6的含量明显增高,后者是导致急性脑梗死的发展机制之一。 相似文献
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目的:观察益气活血中药对肺癌细胞株体外生长抑制及E-CD表达的影响。方法:采用细胞计数、S-P免疫组织化学、图像分析等方法,观察人小细胞肺癌细胞株NC-H446在益气活血中药、全反式维甲酸(ATRA)处理不同时间后细胞生长状况,E-CD表达的影响。结果:在两干预因素下细胞生长抑制,形态改变。中药干预下,NC-H446细胞株E-CD阳性表达率分别由原来的12±8％提高到34±9％,IOD分别由78.5±16.9增加到200.3±21.7,前后相比具有明显差异(P<0.01);中药与ARTA对NC-H446的生长及E-CD表达的影响相比无明显差异(P>0.05)。结论:益气活血中药能明显抑制NC-H446生长,能促进E-CD的正常表达,减弱肿瘤细胞的侵袭转移能力,益气活血中药在上述作用方面可代替ATRA。 相似文献
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目的:观察中西医结合治疗小儿原发性遗尿症的临床疗效。方法:收集我院收治的原发性遗尿患儿64例,随机分为观察组与对照组各32例。对照组予以西医综合治疗,观察组在对照组的基础上加用中药治疗,比较两组的临床疗效。结果:观察组的治疗总有效率为96.9%,显著高于对照组的81.2%(P<0.05);观察组的未复发率显著低于对照组;两组的不良反应率无明显差异(P>0.05)。结论:中西医结合治疗小儿原发性遗尿症疗效显著,可降低复发率,且不良反应少,值得推广应用。 相似文献
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Study progress on mechanism of severe acute pancreatitis complicated with hepatic injury 总被引：4，自引：0，他引：4
Study on the action mechanism of inflammatory mediators generated by the severe acute pancreatitis(SAP) in mul-tiple organ injury is a hotspot in the surgical field.In clinical practice,the main complicated organ dysfunctions are shock,res-piratory failure,renal failure,encephalopathy,with the rate of hepatic diseases being closely next to them.The hepatic injury caused by SAP cannot only aggravate the state of pancreatitis,but also develop into hepatic failure and cause patient death.Its complicated pathogenic mechanism is an obstacle in clinical treatment.Among many pathogenic factors,the changes of vasoac-tive substances,participation of inflammatory mediators as well as OFR(oxygen free radical),endotoxin,etc.may play important roles in its progression. 相似文献
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Study on the action mechanism of inflammatory mediators generated by the severe acute pancreatitis (SAP) in multiple organ injury is a hotspot in the surgical field. In clinical practice, the main complicated organ dysfunctions are shock, respiratory failure, renal failure, encephalopathy, with the rate of hepatic diseases being closely next to them. The hepatic injury caused by SAP cannot only aggravate the state of pancreatitis, but also develop into hepatic failure and cause patient death. Its complicated pathogenic mechanism is an obstacle in clinical treatment. Among many pathogenic factors, the changes ofvasoactive substances, participation of inflammatory mediators as well as OFR (oxygen free radical), endotoxin, etc. may play important roles in its progression. 相似文献
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徽商,一支活跃在明清时期的商帮劲旅,构成了我国封建社会末期商业资本的一个重要力量。而明清时期是徽商发展的鼎盛时期,其活动范围"几遍禹内",在经济发达的江南地区更有着"无徽不成商""无徽不成镇"的说法。两淮地区向来经济发达,又是徽商起步的主要地区,加之交通便利,自然成为徽商经常出入之地。此外,徽商发展不断壮大的一个根本因素是依靠盐业的发展,而扬州作为徽商盐业的基地对徽商发展以及两淮经济的兴衰产生重要影响。 相似文献
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Wolfgang Huber Uli Mayr Andreas Umgelter Michael Franzen Wolfgang Reindl Roland M. Schmid Florian Eckel 《Journal of Zhejiang University. Science. B》2018,19(7):515-524
Background and objective
Stroke volume variation (SVV) has high sensitivity and specificity in predicting fluid responsiveness. However, sinus rhythm (SR) and controlled mechanical ventilation (CV) are mandatory for their application. Several studies suggest a limited applicability of SVV in intensive care unit (ICU) patients. We hypothesized that the applicability of SVV might be different over time and within certain subgroups of ICU patients. Therefore, we analysed the prevalence of SR and CV in ICU patients during the first 24 h of PiCCO-monitoring (primary endpoint) and during the total ICU stay. We also investigated the applicability of SVV in the subgroups of patients with sepsis, cirrhosis, and acute pancreatitis.Methods
The prevalence of SR and CV was documented immediately before 1241 thermodilution measurements in 88 patients.Results: In all measurements, SVV was applicable in about 24%. However, the applicability of SVV was time-dependent: the prevalence of both SR and CV was higher during the first 24 h compared to measurements thereafter (36.1% vs. 21.9%; P<0.001). Within different subgroups, the applicability during the first 24 h of monitoring ranged between 0% in acute pancreatitis, 25.5% in liver failure, and 48.9% in patients without pancreatitis, liver failure, pneumonia or sepsis.Conclusions
The applicability of SVV in a predominantly medical ICU is only about 25%–35%. The prevalence of both mandatory criteria decreases over time during the ICU stay. Furthermore, the applicability is particularly low in patients with acute pancreatitis and liver failure.15.
目的:研究复方金银花和茵陈五苓两种注射液对内毒素所致家兔肾衰中肾脏组织结构的保护作用。方法:将重量2.5±0.25kg的健康雄性家兔32只,随机分为对照组、模型组、复方金银花组和茵陈五苓组,每组8只。模型组、复方金银花组、茵陈五苓组家兔一次性静脉注射大肠杆菌O111B4内毒素生理盐水,剂量为100ug/kg。两保护组家兔注射内毒素24h后静脉注射剂量为100ug/kg的中药注射液。模型组家兔静脉注射同容积的生理盐水。对照组家兔静脉注射与内毒素溶液和中药注射剂等体积的生理盐水。静脉注射内毒素及生理盐水后第7h处死。取肾组织标本,Bouns液固定,石蜡切片,HE染色,显微观察并摄影。结果:模型组肾脏肾小体血管球肿胀,有血栓形成,肾小囊壁层内皮细胞脱落,肾小囊腔变小,肾小管内皮细胞脱落。复方金银花组、茵陈五苓组肾脏的肾小体血管球略有肿胀,肾小囊的内皮细胞较完整,肾小囊腔较对照组稍变小。结论:复方金银花与茵陈五苓对家兔因内毒素所致肾衰中肾脏组织结构有确实的保护作用。 相似文献
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刘利华 《河北北方学院学报(医学版)》2001,18(4):21-22
目的研究急性重症胰腺炎(ASP)的临床治疗.方法对34例ASP的临床资料进行回顾性分析.结果全组34例,治愈27例,治愈率为79.41%.非手术治疗组治愈率为88.89%,手术治疗组治愈率为68.75%.结论ASP非手术治疗的治愈率明显高于手术治疗.早期诊断ASP对选择ASP的治疗方式及改善预后有重要意义. 相似文献
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目的：探讨氨溴索治疗慢性支气管炎急性发作的临床疗效及不良反应.方法：选取慢性支气管炎急性发作患者92例,随机分为对照组44例和观察组48例.对照组患者给予抗感染、祛痰、镇咳、平喘等常规治疗,观察组在对照组基础上加用盐酸氨溴索葡萄糖注射液滴注.结果：观察组临床控制率和总有效率均明显高于对照组（P＜0.05）,观察组平均住院天数明显少于对照组（P＜0.05）,两组均未出现明显不良反应.结论：氨溴索治疗慢性支气管炎急性发作临床疗效佳,且用药安全,可推广应用. 相似文献
18.
Objective: To explore the characteristics of NF-κB activation in the progress of pancreatitis, the relationship with expression of TNF-α in the inflammatory reaction, and prevent the exacerbation of pancreatitis by using NAC. Method: Forty-eight rats were divided into three groups: therapy (group C), pancreatitis (group B) and control (group A). NAC served as the inhibitor of NF-κB activation. In the time intervals of 1.5, 3.0, 6.0, 12.0 hour, NF-κB activation was detected with flow cytometry (FCM) and the expression of TNF-α mRNA and protein with in situ hybridization (ISH) and enzyme-linked immuno-sorbent assay (ELISA) respectively. Meanwhile, the level of lipase and amylase in the serum was assayed and the pathological change was evaluated. Result: NF-κB activation in the pancreatitis group was higher than that in the control group (P<0.01), peaked at 3 hours, and was depressed by the inhibitor of NF-κB, NAC. The expression of TNF-α as well as the level of lipase and amylase in the serum also rose synchronously with activation of NF-κB. In contrast to group A, it was significantly different (P<0.01) in group B. After using NAC in group C, all of these values were decreased and the inflammatory reaction in the pancreas abated evidently. The pathology changes of the pancreas were shown to be alleviated in group C. Conclusion: First, NF-κB activity is intensively initiated in the course of pancreatitis and shown to have closely relationship with the release of cytokines. Second, use of NAC markedly depressed NF-κB activation. TNF-α expression is down regulated by cytokines. It is suggested that NAC probably acts as a useful agent for treatment of pancreatitis by indirectly inhibiting activation of NF-κB. 相似文献
19.
陈翊 《温州职业技术学院学报》2013,(2):17-19,23
十大商帮在明清时期盛极一时,但最终因小农经济意识、区域封闭性和非制度化的企业管理等文化缺陷而湮灭。温州商帮是当今国内成绩最突出的企业家群体之一,但也遭遇发展瓶颈。温州商帮应吸取明清十大商帮的经验及教训,创新思想意识,改变交易方式,完善企业管理制度,建立区域特色文化,以保持活力并延长生命力。 相似文献