共查询到20条相似文献，搜索用时 236 毫秒
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[目的]探讨肛门狭窄以手术方法治疗的疗效.[方法]临床选择肛门狭窄患者12例,2例肛门狭窄采用隔膜切除术,10例肛管狭窄采用纵切横缝术,成人患者加"V-Y"成形术,并结合术后扩肛3个月,观察近远期疗效.[结果]12例患者手术后均排便通畅,随诊2~5a,无一例复发.[结论]不同肛门狭窄采用不同的方法进行治疗有较好疗效. 相似文献
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失眠患者的耳穴诊断及耳穴贴压疗效观察 总被引：1，自引：0，他引：1
[目的]探索大学生失眠患者的耳穴敏感点及耳压治疗效果.[方法]对43例大学生失眠患者和40例健康大学生作了耳穴敏感点测定,同时对患者进行了耳穴贴压治疗.[结果]失眠患者阳性例数在65％以上的敏感点有皮质下、心、神门、枕、垂前、脾等6点,而健康大学生上述6点阳性例数明显减少,经统计学处理,两组有显著性差异(P<0.01).失眠患者治疗后痊愈8例,显效13例,好转18例,无效4例,总有效率为90.7％.[结论]耳穴贴压敏感点治疗失眠疗效满意,可推广应用于学生患者. 相似文献
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[目的]探讨放射状视神经切开术(RON)治疗视网膜中央静脉阻塞(CRVO)的手术效果及其并发症.[方法]选择7例视力0.1或以下的CRVO患者,病程1～6个月,手术常规做睫状体平坦部巩膜三切口玻璃体切除术,应用显微玻璃体视网膜(MVR)切开刀,做一个RON,切口在视盘鼻侧边缘,避开损伤鼻侧视网膜血管,刺入深度约为2.2mm.[结果]7例RON手术都很成功,无有任何并发症发生.术后随访6～12个月,患者眼底表现均有好转,术后视力也都有增进.[结论]RON有助于缺血性CRVO患者视网膜内出血、渗出和黄斑水肿的消退,以及视力的改善,似可适当用于选择性治疗此种难治的眼病. 相似文献
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[目的]探讨冷凝联合小梁切除术治疗新生血管性青光眼的疗效.[方法]A组12例14眼新生血管性青光眼,施行180°视网膜周边部巩膜外和睫状体冷凝;B组20例22眼,除上述冷凝外,又联合小梁切除术治疗.[结果]随访3～6个月,两组术后视力均无明显改善,A组平均眼压自57.48mmHg降至32mmHg,需要再做冷凝或手术减压;B组随访的15例(16眼)有14眼的眼压<21mmHg,2眼需加用0.1%噻吗心安滴眼治疗,两组术后短期内眼压控制有明显的差异(P<0.05).[结论]冷凝或联合小梁切除术对新生血管性青光眼治疗有较好的短期疗效. 相似文献
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目的 :观察和评价经内镜高频电治疗上消化道息肉的疗效及价值。方法 :采用高频电治疗仪通过内窥镜实施治疗操作 ,将圈套器置于息肉根基部稍上方 ,收紧钢丝 ,通电切除。结果 :12 8例 (14 1枚 )息肉切除均获得成功 ,对直径 <2cm一次治疗成功率 10 0 %。 1枚 4cm息肉 ,4次电凝电切治愈 ,均无严重并发症发生。结论 :本方法设备简单 ,操作方便安全 ,疗效确切 ,医疗费用低 ,少见并发症发生[1,2 ] ,为临床治疗息肉的首选方法。 相似文献
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To study the relationship between gastrointestinal dysfunction and motilin in patients with hypothyroidism. The plasma motilin
concentration was measured by radiommunoassay (RIA) in 30 patients with hypothyroidism and also in 30 controls. At the same
time, the electrogastroenterogram was also taken. Among the hypothyroidism patients, 56.6% had decreased gastric motility,
especially in gastric body and greater gastric curvature; 86.6% had decreased colonic motility, especially in the left half
of the colon. There were no significant differences of plasma motilin concentration between patients with hypothyroidism and
controls (P>0.05). There were also no differences between pre-treatment and post-treatment individuals, but significant differences were
observed in the electrogastroenterogram. We conclude that the plasma motilin concertration in hypothyroidism patients was
the same as that in normal patients, and that electrogastroenterogram studies in patients with gastrointestinal dysfunction
may be valuable. 相似文献
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ＩＮＴＲＯＤＵＣＴＩＯＮＢｅｓｉｄｅｓｉｎｔｒｉｎｓｉｃｇａｓｔｒｏｉｎｔｅｓｔｉｎａｌａｂｎｏｒｍａｌｉ ｔｉｅｓ,ｄｙｓｍｏｔｉｌｉｔｙｏｆｇａｓｔｒｏｉｎｔｅｓｔｉｎａｌｔｒａｃｔｓｃａｎａｌｓｏｂｅｃａｕｓｅｄｂｙｅｎｄｏｃｒｉｎｏｌｏｇｉｃｐｒｏｂｌｅｍｓｓｕｃｈａｓｄｉ ａｂｅｔｅｓｍｅｌｌｉｔｕｓ,ｇａｓｔｒｏｐａｒｅｓｉｓｆｏｒｅｘａｍｐｌｅ (Ｒａｔｈ ｍａｎｎｅｔａｌ.,1 991 ) .Ｔｈｅｒｅｌａｔｉｏｎｓｈｉｐｂｅｔｗｅｅｎｇａｓｔｒｏｉｎｔｅｓｔｉｎａｌｄｙｓｆｕｎｃｔｉｏｎａｎｄｐ… 相似文献
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Objective： To investigate the effect of activated protein C （APC） on inflammatory responses in human umbilical vein endothelial cells （HUVEC） stimulated with lipopolysaccharide （LPS）. Methods： The second passage of collagenase digested HUVEC was divided into the following groups： serum free medium control group （SFM control）, phosphate buffer solution control group （PBS control）, LPS group with final concentration of 1 μg/ml （LPS group）, APC group with final concentration of 7 μg/ml, Pre-APC group （APC pretreatment for 30 min prior to LPS challenge）, and Post-APC group （APC administration 30 min after LPS challenge）. Supernatant was harvested at 0, 4, 8, 12 and 24 h after LPS challenge. Interleukin-6 （IL-6） and Interleukin-8 （IL-8） levels were analyzed with ELISA. Cells were harvested at 24 h after LPS challenge, and total RNA was extracted. Messenger RNA levels for IL-6 and IL-8 were semi-quantitatively determined by RT-PCR. Results： Compared with control group, IL-6 and IL-8 levels steadily increased 4 to 24 h after LPS stimulation. APC treatment could increase LPS-induced IL-6 and IL-8 production. The mRNA levels of IL-6 and IL-8 exhibited a similar change. Conclusion： APC can further increase the level of IL-6 and IL-8 induced by LPS. The effect of these elevated cytokines is still under investigation. 相似文献
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武宇宏 《河北北方学院学报(医学版)》2005,22(1):7-11
目的:为了解活化的嗜酸性粒细胞及肥大细胞的脱颗粒情况,应用透射电镜观察嗜酸性粒细胞及肥大细胞的形态变化、颗粒情况及脱颗粒类型,借此探讨嗜酸性粒细胞及肥大细胞在鼻息肉发病机制中的作用,找到一种预防鼻息肉的好方法.方法:鼻息肉组10例,鼻息肉组织来自2001年我科住院做鼻内窥镜手术的多发性鼻息肉病人,男6例,女4例.正常对照组5例,选取同期因鼻外伤住院病人,男4例,女1例.所有组织均在鼻内窥镜下采取,病变组取息肉组织,对照组取下鼻甲组织,标本迅速放入10%甲醛液及4%戊二醛液固定,分别供光镜及电镜检查备检,HE染色及常规电镜制片.结果:光镜下可见大量炎性细胞浸润,以嗜酸性粒细胞为主,主要位于黏膜下,小血管周围;正常对照组炎细胞较少,统计学分析鼻息肉组嗜酸性粒细胞数目明显高于正常对照组,且有显著性差异(P＜0.05).肥大细胞的超微结构特点:正常对照组多为正常肥大细胞,大小基本一致,胞浆内多为高电子密度颗粒,表面可见微绒毛,无空泡形成;鼻息肉组:绝大多数为脱颗粒肥大细胞,表现为颗粒变大、电子密度减低、颗粒间相互融合、颗粒与胞膜融合、空泡形成.另外在息肉组织内可见浆细胞存在,有一较大的核,核内异染色质呈斑块状,分布在核周围,胞浆内充满膨大的粗面内质网,说明蛋白合成旺盛.结论:经研究我们发现鼻息肉组织中有大量的炎性细胞浸润,其中以嗜酸性粒细胞最多,而且大部分是活化状态,嗜酸性粒细胞及肥大细胞脱颗粒后释放炎性介质、细胞毒性蛋白及细胞因子等生物活性物质,引起上皮脱落、组织水肿、血管增生,最终导致鼻息肉的发生和发展,鼻腔局部应用皮质类固醇激素可以抑制炎性细胞的聚集和活化,减轻组织中的炎性反应,从而达到控制鼻息肉的目的. 相似文献
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目的:为提高胃肠外科的带教水平和效果,探索高清腹腔镜手术视频录像在临床带教中的效果。方法:选取2017年7月—2018年7月期间进入胃肠外科的96名临床外科实习医师、研究生和低年制住院医师,每周进行胃肠外科腹腔镜手术视频观看,并安排一名主治以上医师进行现场讲解和答疑。最后通过统一的出科考核并与上一年度的考试成绩进行对比,同时对学生进行问卷调查,评价教学效果。结果:出科考试的平均成绩为86.3±3.7分,高于上一年度的78.8±2.9分(P<0.05);问卷调查结果显示:认为对胃肠和腹部脏器的解剖知识掌握有帮助的达95.5%,对胃肠手术流程和解剖变异学习有帮助的达93.8%,对临床带教有帮助的达96.7%,对带教老师满意度高达100%。结论:视频观看的教学方式更加直观、形象,更具吸引力,更有利于学生掌握临床基础知识;同时可以有效地激发学生的学习兴趣,提高他们对带教的满意度。 相似文献
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Objective: To assess the diagnostic efficiency of OMOM capsule endoscopy (CE) in a group of patients with different indications. Methods: Data from 89 consecutive patients (49 males, 40 females) with suspected small bowel disease who under- went OMOM CE (Jinshan Science and Technology Company, Chongqing, China) examination were obtained by retrospective review. The patients’ indications of the disease consisted of the following: obscure gastrointestinal bleeding (OGIB), abdominal pain or diarrhea, partial i... 相似文献
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分别对无偿自愿献血者的新鲜血浆及冷上清进行留样,并检测其中凝血因子FVIII、FIX、FV、FVII、Fbg及总蛋白含量.检测结果进行统计学分析（t检验）.冷上清中FVIII含量为（0.35±0.13）IU/mL;FIX含量为（0.61±0.15）IU/mL;FV含量为（0.93±0.18）IU/mL;FVII含量为（1.06±0.35）IU/mL;Fbg含量为（142.41±37.77）mg/dL;TP含量为（62.90±5.01）g/L.新鲜冰冻血浆中FVIII、FV、Fbg含量与冷上清中FVIII、FV、Fbg含量相比较,均为P〈0.01,有极显著差异.新鲜冰冻血浆中FIX、FVII、TP含量与冷上清中FIX、FVII、TP含量相比较,均为P〉0.05,无显著差异.结果表明,冷上清中含不稳定因子FV、FVIII,但其含量与新鲜冰冻血浆相比较低.用冷上清对TTP患者行血浆置换后,可使患者凝血系统恢复正常,病情明显好转. 相似文献
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胃肠减压是腹部外科的常见操作技术,重点阐述了腹部外科病人胃肠减压的方法、胃管的选择、插入的深度和固定方法的改进,对胃肠减压期间引流不畅的原因和护理也做了总结,提出要保证有效的胃肠减压需做好心理护理,注意置管方法、置管深度、固定方法及密切观察引流情况。 相似文献
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The diagnostic value of virtual colonoscopy versus colonoscopy was compared in detection of colorectal neoplasia. Virtual
colonoscopy was performed on 29 patients with suspected colorectal diseases, Results were compared with colonoscopy for each
case. Virtual colonoscopy was successfully performed on each patient. All patients tolerated virtual colonoscopy well, had
no complications. All colorectal malignance were identified both by virtual colonoscopy and colonoscopy. Twenty-five polyps
were detected with colonoscopy, whereas only 16 polyps were defined by virtual colonoscopy. Detection rates of polyps greater
than 1.0 cm, between 0.5–0.9 cm and less than 0.5 cm in size were 90%, 62.5% and 28.6% respectively. Virtual colonoscopy is
fast, minimally invasive and well tolerated. This technique is a valuable clinical method in diagnosis of colorectal malignance
and polyps larger than 0.5 cm in size. 相似文献