共查询到19条相似文献，搜索用时 250 毫秒
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目的:对比分析肝脏增强CT检查与肝脏MRI检查在诊断肝癌方面准确率。方法:本次研究对象为肝胆外科就诊的90例患者,均经肝胆彩色B超初筛确诊为肝脏中小型占位病变,分别经肝脏增强CT检查与肝脏MRI检查,并经病理确诊,以病理诊断为金标准评价检查方法的准确率。结果:肝脏MRI扫描准确率明显高于肝脏增强CT检查,有统计学意义(P0.05)。结论:肝脏MRI检查方法诊断肝癌的准确率高于肝脏增强CT检查方法,可作为临床诊断肝癌的首选方法。 相似文献
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本文通过３４例功能失调性子宫出血病人子宫全切除术后,对术前临床诊断及术前术后子宫内膜病理结果分析,符合功血诊断者１３例,占３８．２４％,合并各种器质性病变绪 ２１例,占６１．７６％。 相似文献
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目的 探讨超声对肝癌的诊断价值.方法 对108例肝癌患者进行灰阶超声和彩色多普勒超声分析.结果 108例患者中有72例手术和病理证实,病理报告均为肝细胞肝癌;36例肝癌伴肝外转移失去手术机会.结论 超声检查肝癌方便快捷,彩色多普勒超声检查及彩色多普勒能量图的应用,对明确肝癌诊断有明显的协助作用. 相似文献
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《科学中国人》2015,(14)
目的:探讨超声对剖宫产子宫复旧后检查的临床研究。方法:选取我院2010年7月到2011年8月接收的300例剖宫产手术史的患者和50例自然分娩的产妇,采用超声追踪检查。结果:45%手术后患者子宫的纵径具有显著价值,25%手术后患者子宫峡部长20±5.2mm,P0.05则具备统计学意义,大多数是2次剖宫产史的患者。还有1例66岁的老年患者有两次剖宫产手术史,出现腹泻、腹痛进行钡灌肠检查,显示乙状结肠具有外源性压迫,CT检查显示患者盆腔出现实质性的肿块,采用B超检查,显示子宫体底部没有出现萎缩,子宫峡部长达到5.0cm,随着患者膀胱充盈程度的不同,患者的子宫峡部的长度也有所改变。患者膀胱轻度充盈的时候,峡部显著缩短。为了增加准确性,采用宫腔探针,显示盆腔包块系没有萎缩。还有1例66岁的老年患者有两次剖宫产手术史,出现腹泻、腹痛进行钡灌肠检查,显示乙状结肠具有外源性压迫,CT检查显示患者盆腔出现实质性的肿块,采用B超检查,显示子宫体底部没有出现萎缩,子宫峡部长达到5.0cm,随着患者膀胱充盈程度的不同,患者的子宫峡部的长度也有所改变。患者膀胱轻度充盈的时候,峡部显著缩短。为了增加准确性,采用宫腔探针,显示盆腔包块系没有萎缩。结论:对患者进行超声检查的时候,要多分析患者的病史,再结合临床诊断,降低误诊的概率,尽量采取自然分娩,患者手术后运动可以降低并发症。 相似文献
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宫外孕破裂的早期诊断——附21例临床病例 总被引：1，自引：0，他引：1
目的 为探讨早期诊断宫外孕破裂,减少误诊及病死率.方法 采用日立-2000超声诊断仪,腹部探头率3.5MH2,常规性腹部超声检查.结果 对诊断明确并经手术证实的21例病例分析,子宫多呈轻度增大,子宫内膜不同增原,宫内未见妊娠囊.在21例均发现在附件有包块, 包块最小5×1.2cm,最大为6.5×3.2cm,包块形态均不规则.边界不清楚,回声为乱的混合回声光团.在陶氏包块周围或子宫四周可见大小不一的液性暗区.结论 有闭经史,突然下腹疼痛且持续加重,应优先考虑本病.及时作详细腹部B超检查,结合临床早期手术,挽救生命. 相似文献
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《大众科技》2015,(7)
目的:探讨甲氨喋呤(MTX)+米非司酮+超声引导下清宫术、子宫动脉栓塞术+超声引导下清宫术和孕囊穿刺抽吸术治疗剖宫产后瘢痕妊娠的临床价值。方法:回顾性分析2008年10月至2015年1月广西桂平市人民医院共收治92例剖宫产后瘢痕妊娠(CSP)患者,所有患者经临床及超声检查确诊为CSP,分别使用甲氨喋呤(MTX)+米非司酮+超声引导下清宫术、子宫动脉栓塞术+超声引导下清宫术和孕囊穿刺抽吸术治疗。结果:治疗后,甲氨喋呤(MTX)+米非司酮+超声引导下清宫术组HCG下降理想,但是下降程度不及子宫动脉栓塞术+超声引导下清宫术组和;阴道或经腹部穿刺孕囊抽吸组,住院费用甲氨喋呤(MTX)+米非司酮+超声引导下清宫术组最低,出血量阴道或经腹部穿刺孕囊抽吸组组最低(P0.05)。结论:每个CSP患者应制定个体化的治疗方案。甲氨喋呤(MTX)+米非司酮+超声引导下清宫术疗效不确切,且具有较高风险,子宫动脉栓塞术+超声引导下清宫术和孕囊穿刺抽吸术作为有效、安全的两种方法,值得推广。 相似文献
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本文回顾近9年间被误诊的126例肠伤寒。本组病例曾被诊断为流行性乙型脑炎(重型)、系统性红斑狼疮、急性化脓性阑尾炎、急性细菌性痢疾、肠梗阻、上呼吸道感染以及其它18种病症。误诊的主要原因:(1)对本地区肠伤寒的新近疫情缺乏了解;(2)对现代肠伤寒的临床特点缺乏认识;(3)对肠伤寒的复杂而众多并发症欠熟悉;(4)对肠伤寒诊断的常规实验室检查方法甚显不足;(5)未能采用肠伤寒早期诊断的多项新技术。 相似文献
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Emokpae M. A. Das S. C. Orok T. Mohammed A. Z. Hassan S. A. 《Indian journal of clinical biochemistry : IJCB》2004,19(1):62-66
This study was conducted to investigate the diagnostic performance characteristics of prostate specific antigen (PSA) by comparing
serum PSA value with histological findings in patients suspevted of having prostate cancer in Aminu Kano Teaching Hospital.
Nigeria. Clinical and Laboratory records were examined and collated for serum PSA values, together with histological findings
of biopsy specimen, clinical diagnosis, age of patients, and mode of presentation. The serum PSA values were determined by
ELECSYS 1010 autoanalysers Roche, Germany based on electrochemiluminescence immunoassay technique. The results show that serum
PSA values increase with age in the assymptomatic non-cancer patients who came for medical check up but were within normal
limit. In prostatic disease conditions PSA values were raised in benign prostatic hyperplasia 35.957± 4.0315ng/ml, in undifferentiated
carcinoma 56.22±4.295ng/ml and adenocarcinoma >100ng/ml as compared to the normal range (0–4ng/ml). These cases were confirmed
by histological diagnosis. It is concluded that PSA evaluations is a sensitive marker for prostate cancer but because of various
other conditions that affect serum PSA concentration, other methods of investigations such as Digital Rectal examination,
Trans Urethral Ultra-Sonography and histological examination should be combined to confirm diagnosis. Prognosis of patients
will be better if early diagnosis is made. 相似文献
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Diana Nakidde Phillip Zellner Mohammad Mehdi Alemi Tyler Shake Yahya Hosseini Maria V. Riquelme Amy Pruden Masoud Agah 《Biomicrofluidics》2015,9(1)
In this study, a 3D passivated-electrode, insulator-based dielectrophoresis microchip (3D πDEP) is presented. This technology combines the benefits of electrode-based DEP, insulator-based DEP, and three dimensional insulating features with the goal of improving trapping efficiency of biological species at low applied signals and fostering wide frequency range operation of the microfluidic device. The 3D πDEP chips were fabricated by making 3D structures in silicon using reactive ion etching. The reusable electrodes are deposited on second glass substrate and then aligned to the microfluidic channel to capacitively couple the electric signal through a 100 μm glass slide. The 3D insulating structures generate high electric field gradients, which ultimately increases the DEP force. To demonstrate the capabilities of 3D πDEP, Staphylococcus aureus was trapped from water samples under varied electrical environments. Trapping efficiencies of 100% were obtained at flow rates as high as 350 μl/h and 70% at flow rates as high as 750 μl/h. Additionally, for live bacteria samples, 100% trapping was demonstrated over a wide frequency range from 50 to 400 kHz with an amplitude applied signal of 200 Vpp. 20% trapping of bacteria was observed at applied voltages as low as 50 Vpp. We demonstrate selective trapping of live and dead bacteria at frequencies ranging from 30 to 60 kHz at 400 Vpp with over 90% of the live bacteria trapped while most of the dead bacteria escape. 相似文献
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Luigi M Castello Sophie Negro Francesca Santi Isabella Zanotti Matteo Vidali Marco Bagnati Giorgio Bellomo Gian Carlo Avanzi 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2012,22(3):380-384
Introduction:
Two Italian adults arrived at the Emergency Department referring diarrhea, nausea and vomiting for 4 days; weakness, fatigue and visual hallucinations were also complained of. Patients reported the ingestion of some leaves of a plant, which they supposed to be “donkey ears”, a week before. Physical examination showed hypotension and bradycardia and ECG examination disclosed sinus rhythm and repolarization abnormalities (scooping of the ST-T complex) in both patients and a 2:1 AV block in the man.Materials and methods:
Digoxin concentration was evaluated twice for each patient (at the admission and after 4 hours) by the automated immunoassay system ADVIA Centaur®. Digitoxin concentration was evaluated by liquid chromatography-mass spectrometry (LC-MS/MS).Results:
Despite clinical picture was suggestive of digitalis intoxication, digoxin levels were undetectable. Due to the more severe clinical picture, the male patient was treated with anti-digoxin antibodies (Digifab®) achieving a good clinical improvement and remission of the AV block within two hours. Initial diagnosis was confirmed by LC-MS/MS showing high digitoxin concentrations, but digoxin was undetectable. Patients remained stable and 48 hours later were discharged from the hospital.Conclusion:
Whereas digoxin determination frequently relies on monoclonal antibodies which do not cross-react to digitoxin, polyclonal antibodies constituting Digifab® recognize a large spectrum of cardiac glycosides, including digitoxin. This report emphasizes the primary role of the clinical approach to patients in the emergency setting and how an active communication and a continuous sharing of professional experiences between Laboratory and Clinicians ensure an early and correct diagnosis. 相似文献15.
Rohit Kumar Gupta Sagar Jayantilal Dholariya Smita Kaushik S. K. Gupta Reva Tripathi Shyam Lata Jain 《Indian journal of clinical biochemistry : IJCB》2021,36(2):221
Ovarian cancer has been emerged as a most common and lethal gynecological malignancy in India. High serum insulin and low adiponectin have been associated with increased risk of ovarian cancer. But their role in development of ovarian cancer is conflicting and little evidence is available. We aimed to evaluate blood levels of insulin and adiponectin in epithelial ovarian cancer (EOC) patients and their association with the risk to develop EOC. The study included following three groups; Group 1: fifty cases of cytohistopathologically confirmed cases of EOC, Group 2: fifty age matched cases of benign ovarian conditions and Group 3: fifty ages matched healthy controls with no evidence of any benign or malignant ovarian pathology as ruled out by clinical examination and relevant investigations. Cytohistopathologically confirmed and newly diagnosed cases of EOC and benign ovarian cancer were included in this study. The median value of fasting serum insulin was significantly high (15.0 µlU/ml, P = 0.02) and adiponectin were significantly low (5.1 µg/ml, P < 0.001) in ovarian cancer patients compared to benign ovarian tumors and healthy controls group. A significant increase risk of ovarian cancer was found in high tertile (≥ 18.7 µlU/ml) of serum insulin level (OR = 2.7; 95% CI = 1.00–6.67, P = 0.04) and lower tertile (≤ 5.45 µg/ml) of adiponectin level (OR = 3.2; 95% CI = 1.10–9.71, P = 0.03). High serum insulin level and low adiponectin levels were significantly associated with increased risk for development of ovarian cancer. 相似文献
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Emma Whittle Elzahn de Waal Tony Huynh Oliver Treacy Adam Morton 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2021,31(1)
We describe a case of severe hypervitaminosis D and mild hypercalcaemia in a 68-year-old woman who presented with fatigue and weight loss. Her 25-hydroxy vitamin D (25OHD) was > 400 nmol/L (50-150) and corrected serum calcium was 2.83 mmol/L (2.1-2.6). Her intact parathyroid hormone (PTH) was 4.9 pmol/L (2.0-9.5). Further investigation revealed an IgM kappa paraprotein, and a bone marrow aspirate confirmed a diagnosis of lymphoplasmacytic lymphoma/Waldenstrom’s macroglobulinemia (LPL/WM). As the vitamin D level was discordant with the patient’s other results and presentation, the presence of an assay interferent was suspected. A 1-in-2 dilution of the sample returned a 25OHD result of 84 nmol/L in keeping with the presence of an interferent. Testing for rheumatoid factor was negative. The sample was treated with an antibody blocking reagent (Scantibodies) and results were not consistent with heterophile antibody interference. The sample was then analysed using liquid chromatography tandem mass spectrometry (LC-MS/MS), which returned a 25OHD result of 82 nmol/L. Testing on an alternative immunoassay platform produced a 25OHD result of 75 nmol/L. Reapeted testing on the original platform following reduction of the monoclonal paraprotein with chemotherapy, returned a result of 64 nmol/L. The patient’s mild hypercalcaemia persisted following resolution of the monoclonal paraprotein, in keeping with a diagnosis of primary hyperparathyroidism. This case highlights the potential for paraproteins to cause assay interference, and the importance of considering interference when results are incongruous with the clinical presentation. 相似文献
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Among various transdermal drug delivery (TDD) approaches, utilizing the microneedles (MNs) not only can penetrate the skin but also deliver the drug with reduced tissue damage, reduced pain, and no bleeding. However, the MNs with larger height are required to overcome the skin barrier for effective TDD. Unlike 2D patterning, etching polydimethyl siloxane (PDMS) micropillars for fabrication of 3D microstructures is presented. The PDMS micropillars were first constructed by casting PDMS on the computer numerical control-machined cylindrical microwells, which then went through etching process to obtain the MNs for subsequent fabrication of polymer MNs or high aspect ratio micropillars. 相似文献
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探讨了胰腺癌血管受累的ＣＴ分型与肿瘤手术可切除性的关系．对４３例经手术、病理证实的胰腺癌进行薄层ＣＴ动态扫描，根据确定的ＣＴ标准，观察肿瘤与血管的关系，并与手术结果对照．发现胰腺癌血管受累以Ｃ型最常见，占３７．２％，Ａ型１０例，肿瘤切除率１００％（１０／１０），Ｂ型９例，切除率为７７．８％（７／９），Ｃ型、Ｄ型２４例，均不可切除．表明薄层ＣＴ动态扫描能提高胰腺癌血管受累的诊断正确率，血管受累ＣＴ分型对外科制定手术计划具有一定价值． 相似文献
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This paper explores five competing theories for technological knowledge sharing within the globally dispersed R&D function of the multidivisional, multinational firm. These five broad explanations for why a knowledge transaction occurs are: (1) economic, (2) technological, (3) organizational, (4) geographic, and (5) sociological. In addition to occurrence, likelihood of knowledge exchange success prompted by various explanations is considered. Ultimately the determination of which argument—or combination of arguments—offers the greatest explanatory power for the sharing of intermediate technological knowledge may be answered empirically. 相似文献