Serum and tissue levels of zinc,copper, magnesium and retinol in prostatic neoplasms     

M. Jain  Kavita Sharma  V. P. Sharma 《Indian journal of clinical biochemistry : IJCB》1994,9(2):106-108

Zinc (Zn), copper (Cu), magnesium (Mg) and retinol levels were studied in serum and tissue of the patients with prostatic carcinoma (Ca), benign hyperplasia (BHP) and control subjects. Zinc and retinol levels were low in both serum and tissues of patients with carcinoma, while in BHP, both zinc and retinol level were decreased. Copper levels were high in serum and tissues of both BHP as well as carcinoma patients. Magnesium levels were elevated in both serum and tissues of cancerous patients. The results indicate that Zn, Cu, and Mg metabolism is disturbed in malignancy.  相似文献   

Comparison of two methods of estimation of low density lipoprotein cholesterol, the direct versus friedewald estimation     

Suchanda Sahu MBBS  MD  Rajinder Chawla  Bharti Uppal 《Indian journal of clinical biochemistry : IJCB》2005,20(2):54-61

Current recommendations of the Adult Treatment Panel and Adolescents Treatment Panel of National Cholesterol Education Program make the low-density lipoprotein cholesterol (LDL-C) levels in serum the basis of classification and management of hypercholesterolemia. A number of direct homogenous assays based on surfactant/solubility principles have evolved in the recent past. This has made LDL-C estimation less cumbersome than the earlier used methods. Here we compared one of the direct homogenous assays with the widely used Friedewald’s method of estimation of LDL-C to see the differences and correlation. We used direct homogenous assay kit to estimate serum LDL-C and high-density lipoprotein cholesterol (HDL-C). Serum Triglyceride (TG) and Total Cholesterol (TC) was estimated and using Friedewald’s formula LDL-C was calculated. The LDL-C level obtained by both methods in 893 fasting serum samples were compared. The statistical methods used were paired t-test and Pearson’s correlation. There was significant difference in the mean LDL-C levels obtained by the two methods at the TG levels <200 mg/dl (p<0.02) and TC levels >150 mg% (p<0.001). The correlation coefficient (r) between Friedewald’s and direct assay estimation was 0.88. Friedewald’s method classified 23.5 % of patients as high cardiac risk whereas there were 17.58% by direct assay. Both had good correlation even though the serum triglyceride and total cholesterol levels affect the difference in LDL-C estimated by both methods. Taking into account the cost and performance, Friedewald’s method is as good or even better for classifying and managing patients.  相似文献   

Emerging problems in Malaria control     

V. P. Sharma 《Indian journal of clinical biochemistry : IJCB》1997,12(1):4-4

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开展机构协作发展远程教育     

肖俊洪 《中国远程教育(综合版)》2004,(7):29-32

[译者按]本文原文发表于"学习联邦"(Com-monwea]th of Learning)网站<知识系列>(Know]-edge Series)栏目(2003年).学习联邦是英联邦各成员国的政府首脑倡议成立的政府间组织,其宗旨是鼓励开发和共享开放学习和远程教育的知识、资源和技术.目前我国远程教育机构也正在开展各种形式的协作,既有电大之间的协作,也有电大与其他教育机构的协作,还有国际间的协作,但毕竟一切刚刚起步,许多地方有待于进一步完善.因此,我们认为这篇经验之谈的文章所提出的一些原则、建议、指南等对我们有一定指导意义和借鉴价值.现将其译成中文,以飨读者,并向印度甘地国立开放大学Sharma高级讲师和Chaudhary教授以及学习联邦组织致谢!  相似文献   

Substituent effect of the methoxy group: A matter of give and take     

Gurumayum S. D. Sharma  S. V. Eswaran 《Resonance》1997,2(3):73-75

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Learning foodchain with <Emphasis Type="Italic">Calotropis Procera</Emphasis>     

Dilip Amritphale  Santosh Sharma 《Resonance》2007,12(1):67-75

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‘I don't have time to be this busy.’ Exploring the concerns of secondary school teachers towards inclusive education     

Penny N. Round  Pearl K. Subban  Umesh Sharma 《International Journal of Inclusive Education》2016,20(2):185-198

The trend towards inclusion in mainstream Australian schools has seen the numbers of students with disabilities educated in regular schools grow significantly. This trend has been supported by legislation such as the Disability Discrimination Act and the Education Standards. For inclusion to be successful, a number of factors are vital and teacher support for the programme is crucial. While there is research in the area of teachers’ concerns at the primary school level, little research has been conducted at the secondary school level. Research in this area is needed as the secondary school has differing factors from the primary sector that need to be explored.  相似文献   

Language acquisition by distance education: an Australian survey     

Sylvia Williams  Pramod Sharma 《Distance Education》1988,9(1):127-146

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Current Scenario of Prevalence of Vitamin D Deficiency in Ostensibly Healthy Indian Population: A Hospital Based Retrospective Study     

Kirtikar Shukla  Shikha Sharma  Aditi Gupta  Arun Raizada  Kamini Vinayak 《Indian journal of clinical biochemistry : IJCB》2016,31(4):452-457

25-hydroxy vitamin D [25(OH) vit D] deficiency is a serious public health problem, particularly in the Indian sub-continent. The objective of the present study was to study the prevalence of 25(OH) vit D in different age groups. The data of 25(OH) vit D assay of 26,346 ostensibly healthy individuals, enrolled under executive health checkup at Medanta The Medicity, Gurgaon, over a period of 3 years, were extracted from the hospital information system and reviewed extensively. 25(OH) vit D deficiency (VDD) was defined as 25(OH) vit D < 20 ng/ml, insufficiency (VDI) as 25(OH) vit D between 20 and 40 ng/ml and 25(OH) vit D sufficiency (VDS) as 25(OH) D > 40 ng/mL. 25(OH) vit D deficiency (VDD + VDI) was observed in 93 % of the subject population. Maximum number of the subjects belonged to the age group of 41–60 years. 59 % had frank 25(OH) vit D deficiency when cut off level was <20 ng/mL. Mean value of 25(OH) vit D in our subjects was 21.4 ± 14.4 ng/mL. Significant difference in 25(OH) vit D level was observed in between male and female subjects. Simultaneously 25(OH) vit D levels were significantly lower in the patient visited hospital in winter-spring season than the summer-autumn season (p > 0.001). Our study demonstrates a high prevalence of 25(OH) vit D deficiency in an ostensibly healthy Indian population. There is a need for redefining our reference ranges according to our population and extensively improving the status of vitamin D.  相似文献   

Study of serum lactate dehydrogenase in strangulated and non-strangulated intestinal obstruction     

D. S. Dhiman  N. K. Sarin  R. K. Sharma  J. R. Kanwar  R. M. Pathak  R. L. Gupta 《Indian journal of clinical biochemistry : IJCB》1989,4(1):23-25

The present study has been conducted in 80 cases, out of which 28 were of strangulated and 52 of non-strangulated intestinal obstruction. It has been observed that serum lactate dehydrogenase of more than 300 I. U./litre in first 24 hours to 72 hours is highly suggestive of strangulated intestinal obstruction.  相似文献