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Individual Differences in Childhood Behavior Disorders Associated With Epigenetic Modulation of the Cortisol Receptor Gene 下载免费PDF全文
Mark R. Dadds Caroline Moul David J. Hawes Antonio Mendoza Diaz John Brennan 《Child development》2015,86(5):1311-1320
Behavioral/emotional difficulties in children are the first sign of mental health problems. These problems are however, heterogeneous. A domain that may identify homogenous subgroups is hypothalamic–pituitary–adrenal function. This study tested whether epigenetic regulation of glucocorticoid receptor gene could explain the co‐occurrence of anxiety problems in children with behavior problems. Four‐ to 16‐year‐old clinically referred children (N = 241) were measured for psychiatric symptoms, methylation of target CpG sites in blood or saliva, and morning cortisol levels in those who gave blood. Increased methylation of promoter 1F CpG sites was associated with higher vulnerability to co‐occurring internalizing symptoms and morning cortisol. The results support increasing optimism that epigenetic regulation of key neuroendocrine systems might help explain hitherto unfathomable individual differences in susceptibility to psychiatric symptom profiles. 相似文献
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AbstractThis paper is intended as an exploration of university faculty and students’ perceptions of a number of dimensions involved in the written composition of academic texts. We analysed the responses to scale 3 in the European Writing Survey (EUWRIT) (in its Spanish version: Encuesta Europea sobre la Escritura Académica, EEEA) by a group of social science and humanities students (n = 1,030) and faculty (n = 230) from nine Spanish universities. We then examined the similarities and differences in their perceptions and established a factorial structure of the different dimensions underlying the writing process. The data indicate that both groups concur in the value assigned to both changing ideas in the course of the composition process (although this process seems to be understood differently by each group) and the revision and feedback processes. The students, however, claim to be involved in more planning and previous reading activities than the teachers perceive them to be. The significance of these results for a process-oriented perspective in academic writing is discussed. 相似文献
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Panadero Ernesto Pérez Daniel García Ruiz Javier Fernández Fraile Juan Sánchez-Iglesias Iván Brown Gavin T. L. 《European Journal of Psychology of Education - EJPE》2023,38(3):1031-1051
European Journal of Psychology of Education - This study explores the effects of feedback type, feedback occasion, and year level on student self-assessments in higher education. In total, 126... 相似文献
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Miriam Delgado-Verde Javier Amores-Salvadó Gregorio Martín-de Castro José Emilio Navas-López 《知识管理研究与实践》2014,12(3):261-275
Although the importance of intellectual capital has already been highlighted in the management literature, few articles have focused on the importance of its green counterpart, green intellectual capital. Nowadays, when environmental concerns cannot be ignored by firms, it is therefore time to explore the role of green intellectual capital in environmental improvement. For that reason, our research aims to explore the relationships between green intellectual capital components and the environmental performance of the firms. In particular, we try to show the importance of green organizational and social capital in the development of environmental product innovations, which are vital to the development and implementation of environmental strategies since, as scholars have pointed out, they generate some of the greatest environmental impacts. The empirical results show that green organizational capital has an indirect impact on environmental product innovation through green social capital, meaning that the latter is a significant mediator of that relationship, and at the same time emphasizing that informal relationships play a key role in the improvement of the environmental performance of the firm and, more specifically, in the development of environmental product innovations. 相似文献
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Javier Noya Salces Pedro M. Gómez-Carmona Diego Moliner-Urdiales Manuel Sillero-Quintana 《Journal of sports sciences》2014,32(13):1263-1270
AbstractThe aim was to examine the injuries sustained by Spanish football players in the First Division and to compare injury-related variables in the context of both competition and training. The injury data were prospectively collected from 16 teams (427 players) using a specific web-based survey during the 2008/2009 season. A total of 1293 injuries were identified (145 were recurring injuries). The overall injury incidence was 5.65 injuries per 1000 h of exposure. Injuries were much more common during competition than during training (43.53 vs. 3.55 injuries per 1000 h of exposure, P < 0.05). Most of the injuries (89.6%) involved the lower extremities, and overuse (65.7%) was the main cause. Muscle and tendon injuries were the most common types of injury (53.8%) among the players. The incidence of training injuries was greater during the pre-season and tended to decrease throughout the season, while the incidence of competition injuries increased throughout the season (all P < 0.05). In conclusion, the results of this study suggest the need for injury prevention protocols in the First Division of the Spanish Football League to reduce the number of overuse injuries in the muscles and tendons in the lower extremities. In addition, special attention should be paid during the pre-season and the competitive phase II (the last four months of the season) in order to prevent training and competition injuries, respectively. 相似文献
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Studies with adults suggest that implicit preferences favoring White versus Black individuals can be reduced through exposure to positive Black exemplars. However, it remains unclear whether developmental differences exist in the capacity for these biases to be changed. This study included 369 children and examined whether their implicit racial bias would be reduced following exposure to positive Black exemplars. Results showed that children's implicit pro‐White bias was reduced following exposure to positive Black exemplars, but only for older children (Mage = ~10 years). Younger children's (Mage = ~7 years) implicit bias was not affected by this intervention. These results suggest developmental differences in the malleability of implicit racial biases and point to possible age differences in intervention effectiveness. 相似文献
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As Colombia began to develop its Intangible Cultural Heritage (ICH) policy, it signed an agreement with the Smithsonian Center for Folklife and Cultural Heritage to collaborate on a Smithsonian Folklife Festival of Colombia's national living traditions, to be shown on the National Mall in 2011. This essay addresses the role of the Smithsonian Folklife Center in advocating for a cultural heritage policy grounded in cultural democracy and intercultural dialogue, as well as its collaboration with UNESCO in crafting the 2003 convention for the protection of intangible cultural heritage. We focus on the Center's signature collaborative program, the Smithsonian Folklife Festival, and on our experience with the 2011 Festival program, Colombia: The Nature of Culture. We examine the relationship between the Festival and Colombia's intangible cultural heritage communities, policies, and practices, through intercultural dialogues that contribute to shaping Intangible Cultural Heritage policy from the bottom up. 相似文献
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ABSTRACT The purpose was to examine the feasibility of the 20m shuttle run test with music and to test its concurrent validity with the original 20m shuttle run test. A total of 386 adolescents (14.5±1.6 years old, 48.9% boys) participated in our study. A self-reported questionnaire was used to assess student’s perception about the 20m shuttle run test with music and the original and to assess perceived exertion. Participants performed randomly the 20m shuttle run test with music and original two weeks apart. Average and maximum heart rate were monitored with heart rate monitors. The 20m shuttle run with music was a feasible test for measuring cardiorespiratory fitness in adolescents. The concurrent validity showed mean differences of 5.1±14.6 for shuttles, 0.3±0.8 km/h for speed, 0.5±4.1 for stages, and 1.5±4.1 for VO2max (all p<0.001) in favour of the 20m shuttle run with music vs. the original 20m shuttle run test. Mean difference for the rating of perceived exertion was 0.4±2.5 points (p=0.003). No significant difference was found between boys and girls. In conclusion, the 20mSRT-music is feasible and presents a good concurrent validity in adolescents, independently of the sex and it will be an alternative and good approach to assess cardiorespiratory fitness. 相似文献