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31.
We developed a criterion-referenced student rating of instruction (SRI) to facilitate formative assessment of teaching. It involves four dimensions of teaching quality that are grounded in current instructional design principles: Organization and structure, Assessment and feedback, Personal interactions, and Academic rigor. Using item response theory and Wright mapping methods, we describe teaching characteristics at various points along the latent continuum for each scale. These maps enable criterion-referenced score interpretation by making an explicit connection between test performance and the theoretical framework. We explain the way our Wright maps can be used to enhance an instructor’s ability to interpret scores and identify ways to refine teaching. Although our work is aimed at improving score interpretation, a criterion-referenced test is not immune to factors that may bias test scores. The literature on SRIs is filled with research on factors unrelated to teaching that may bias scores. Therefore, we also used multilevel models to evaluate the extent to which student and course characteristic may affect scores and compromise score interpretation. Results indicated that student anger and the interaction between student gender and instructor gender are significant effects that account for a small amount of variance in SRI scores. All things considered, our criterion-referenced approach to SRIs is a viable way to describe teaching quality and help instructors refine pedagogy and facilitate course development.  相似文献   
32.
Many children have significant mathematical learning disabilities (MLD, or dyscalculia) despite adequate schooling. The current study hypothesizes that MLD partly results from a deficiency in the Approximate Number System (ANS) that supports nonverbal numerical representations across species and throughout development. In this study of 71 ninth graders, it is shown that students with MLD have significantly poorer ANS precision than students in all other mathematics achievement groups (low, typically, and high achieving), as measured by psychophysical assessments of ANS acuity (w) and of the mappings between ANS representations and number words (cv). This relation persists even when controlling for domain-general abilities. Furthermore, this ANS precision does not differentiate low-achieving from typically achieving students, suggesting an ANS deficit that is specific to MLD.  相似文献   
33.
产业集群对区域乃至国家经济发展具有重要的作用,然而产业集群发展过程中的影响因素及其相互作用机制至今仍未得到系统的阐述.从协同演进理论视角,结合组织生态学、制度理论、战略管理理论和社会网络理论等,对天津自行车产业集群的发展历程展开多层次、时间序列的分析,以深入挖掘产业集群发展过程中各种要素的相互作用、协同演进机制,提出产业集群的发展是企业战略、产业环境以及制度环境协同演进的过程,同时集群发展过程中创业者的社会资本发挥重要作用.这种将多维理论视角相结合起来进行分析的方法,有利于更好地理解产业集群的演进机制.  相似文献   
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Although there are challenges in delivering a quality improvement initiative at academic medical centers, the potential benefits to resident physicians‐in‐training, hospitals, and patients are significant. This article describes the effects of an institution‐wide effort. Resident physicians‐in‐training from four medical specialty programs partnered with hospital staff while working on team quality‐improvement projects. We tracked clinical outcomes and used validated assessments. The results showed improvements in learning and organizational culture.  相似文献   
36.
Three experiments examined the effect of systemic administration of the benzodiazepine midazolam on extinction and re-extinction of conditioned fear. Experiment 1 demonstrated that midazolam administration prior to extinction of a conditioned stimulus (CS) impaired that extinction when rats were subsequently tested drug free; however, extinction was spared if rats were extinguished, reconditioned, and re-extinguished under midazolam. Experiment 2 provided a replication of this effect within-subjects; rats were conditioned to two CSs (A and B), extinguished to one (A-), reconditioned to both, and then extinguished/re-extinguished to both stimuli in compound (AB-), under either vehicle or midazolam. On the drug-free test, rats given midazolam froze more to the CS that had been extinguished (B) than the one that been re-extinguished (A). The final experiment examined whether extinction under midazolam was regulated by prediction error. Rats were trained with three CSs (A, B, C) and extinguished to two (A-, C-). These stimuli then underwent additional extinction under midazolam or vehicle, with one CS now presented in compound with the non-extinguished CS (AB-, C-). Rats were then tested for fear of A relative to C. Rats given vehicle showed a deepening of extinction to A relative to C, as is predicted from error-correction models; however, rats given midazolam failed to show any such discrepancy in responding. The results are interpreted to indicate that the drug reduced prediction error during extinction by reducing fear, and rats were able to re-extinguish fear via a retrieval mechanism that is independent of prediction error.  相似文献   
37.
To date, a limited number of aqueous conditions have been tested experimentally as potential cleaning reagents on modern acrylic paint films. Those assessed have tended to extract measurable quantities of paint film components and distort the paint films physically. In this paper the results of a series of experiments designed to examine pH, conductivity, and specific ion effects of potential aqueous cleaning solutions on a series of commercial acrylic paints are reported. A three-dimensional microscopic technique was used to characterize the physical (volume and surface roughness) changes and liquid chromatography-tandem mass spectrometry was used to characterize the chemical (extracted surfactant) changes following paint film exposure to the aqueous solution. The tested paint films in this study clearly exhibit an isotonic point below which swelling and extraction is significant, and above which the swelling and extraction is diminished. Manipulation of conductivity and the ionic species in solution can reduce both the physical film changes and surfactant extraction from acrylic paint films; while pH appears to be of limited use in controlling aqueous cleaning effects. Moreover, there seems to be a specific ion effect for both swelling and de-swelling in acrylic paint films that can be rationalized through the Hofmeister Series.  相似文献   
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39.
In this paper, a detailed numerical and experimental investigation into the optimisation of hydrodynamic micro-trapping arrays for high-throughput capture of single polystyrene (PS) microparticles and three different types of live cells at trapping times of 30 min or less is described. Four different trap geometries (triangular, square, conical, and elliptical) were investigated within three different device generations, in which device architecture, channel geometry, inter-trap spacing, trap size, and trap density were varied. Numerical simulation confirmed that (1) the calculated device dimensions permitted partitioned flow between the main channel and the trap channel, and further, preferential flow through the trap channel in the absence of any obstruction; (2) different trap shapes, all having the same dimensional parameters in terms of depth, trapping channel lengths and widths, main channel lengths and widths, produce contrasting streamline plots and that the interaction of the fluid with the different geometries can produce areas of stagnated flow or distorted field lines; and (3) that once trapped, any motion of the trapped particle or cell or a shift in its configuration within the trap can result in significant increases in pressures on the cell surface and variations in the shear stress distribution across the cell’s surface. Numerical outcomes were then validated experimentally in terms of the impact of these variations in device design elements on the percent occupancy of the trapping array (with one or more particles or cells) within these targeted short timeframes. Limitations on obtaining high trap occupancies in the devices were shown to be primarily a result of particle aggregation, channel clogging and the trap aperture size. These limitations could be overcome somewhat by optimisation of these device design elements and other operational variables, such as the average carrier fluid velocity. For example, for the 20 μm polystyrene microparticles, the number of filled traps increased from 32% to 42% during 5–10 min experiments in devices with smaller apertures. Similarly, a 40%–60% reduction in trapping channel size resulted in an increase in the amount of filled traps, from 0% to almost 90% in 10 min, for the human bone marrow derived mesenchymal stem cells, and 15%–85% in 15 min for the human embryonic stem cells. Last, a reduction of the average carrier fluid velocity by 50% resulted in an increase from 80% to 92% occupancy of single algae cells in traps. Interestingly, changes in the physical properties of the species being trapped also had a substantial impact, as regardless of the trap shape, higher percent occupancies were observed with cells compared to single PS microparticles in the same device, even though they are of approximately the same size. This investigation showed that in microfluidic single cell capture arrays, the trap shape that maximizes cell viability is not necessarily the most efficient for high-speed single cell capture. However, high-speed trapping configurations for delicate mammalian cells are possible but must be optimised for each cell type and designed principally in accordance with the trap size to cell size ratio.  相似文献   
40.
Web hyperlink analysis has been a key topic of Webometric research. However, inlink data collection from commercial search engines has been limited to only one source in recent years, which is not a promising prospect for the future development of the field. We need to tap into other Web data sources and to develop new methods. Toward this end, we propose a new Webometrics concept that is based on words rather than inlinks on Webpages. We propose that word co-occurrences on Webpages can be a measure of the relatedness of organizations. Word co-occurrence data can be collected from both general search engines and blog search engines, which expands data sources greatly. The proposed concept is tested in a group of companies in the LTE and WiMax sectors of the telecommunications industry. Data on the co-occurrences of company names on Webpages were collected from Google and Google Blog. The co-occurrence matrices were analyzed using MDS. The resulting MDS maps were compared with industry reality and with the MDS maps from co-link analysis. Results show that Web co-word analysis could potentially be as useful as Web co-link analysis. Google Blog seems to be a better source than Google for co-word data collection.  相似文献   
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