Investigation of the Effects of Inulin and β-Glucan on the Physical and Sensory Properties of Low-Fat Beef Burgers Containing Vegetable Oils: Optimisation of the Formulation Using D-Optimal Mixture Design     

Roya Afshari  Hedayat Hosseini  Ramin Khaksar  Mohammad Amin Mohammadifar  Zohre Amiri  Rozita Komeili  Amin Mousavi Khaneghah 《Food Technology and Biotechnology》2015,53(4):436-445

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Determination of Biological Variance and Validation of a Fluorometric Assay for Measurement of α-l-Iduronidase Activity in Dried Blood Spots Samples: The First Experience in Iran     

Mohammad Abdi  Mohammad Said Hakhamaneshi  Mohammad Reza Alaei  Namam-Ali Azadi  Rahim Vakili  Daniel Zamanfar  Mohammad Taghikhani  Shohreh Khatami 《Indian journal of clinical biochemistry : IJCB》2015,30(3):318-322

Methods for assaying lysosomal diseases in dried blood samples are very useful today due to its several advantages related to the stability of samples, its transportation, handled and analysis, and its potential use for newborn screening compared to traditional methods in leucocytes samples. For this reason, it is important to validate these assays before being used in routine laboratory. Because of different in biological markers based on ethnicity, we aimed this study to validation a DBS-based fluorometric assay for measurement of α-l-Iduronidase activity for diagnosis of MPS I patients in Iran. DBS samples were collected from 15 MPS I patients and 60 healthy age matched subjects. Diagnostic value, biological variance and α-l-Iduronidase activity were determined. DBS α-l-Iduronidase activity was significantly higher in male subjects than in female group. Using a cut-off level of 1.08 µmol/spot 20 h, sensitivity and specificity were 100 and 98 %. The linearity of test was proved and we showed that within-run and between run precision were 5.6 and 14.66 %. Measurement of α-l-Iduronidase activity in DBS samples is an accurate test for diagnosis of MPS I and because of its rapid shipping and simplicity to keeping, DBS-based enzyme activity could be considered as a useful diagnostic tool in this disease.  相似文献   

Microfluidic assessment of swimming media for motility-based sperm selection     

Lise Eamer  Reza Nosrati  Marion Vollmer  Armand Zini  David Sinton 《Biomicrofluidics》2015,9(4)

Selection medium is important in sperm isolation for assisted reproductive technologies. Contrary to the naturally occurring human cervical mucus which has a high viscosity, most current practices for motility based sperm selection use a low viscosity medium. In this study, we used a microfluidic device to assess the effects of high viscosity media made with hyaluronic acid (HA) and methyl cellulose (MC) on bovine and human sperm motility and viability (sperm transferred directly from cryoprotectant). The microfluidic penetration test, viability, and motility were compared for sperm swimming in both HA and MC media with about 20cp viscosity (measured at 20 °C). Our resulted indicate that MC medium resulted in a significantly higher number of viable bovine sperm penetrating the medium as compared to HA. Furthermore, MC resulted in the selection of a sperm subpopulation with a 274% increase in sperm viability in comparison to the raw semen, while HA increased viability by only 133%. In addition to viability, bovine sperm motility parameters were significantly higher in the MC medium as compared with HA. Experiments with human sperm swimming in MC indicate that sperm swim slower and straighter at higher viscosities. In conclusion, the results indicate that in a micro-confined environment representative of the in vivo environment, MC is a preferred high viscosity medium to ensure the highest concentration of motile and viable sperm.  相似文献   

The Effect of Group Logotherapy on Meaning in Life and Depression Levels of Iranian Students     

Somaye Robatmili  Faramarz Sohrabi  Mohammad Ali Shahrak  Siavash Talepasand  Mostafa Nokani  Mohaddese Hasani 《International journal for the advancement of counseling》2015,37(1):54-62

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Hasse,Cathrine (2015) An anthropology of learning. Springer (Berlin) isbn 978‐94‐017‐9605‐7 320 pp £90 (ebook £72) http://www.springer.com/us/book/9789401796057#          下载免费PDF全文

Mohammad Ali Salmani Nodoushan 《British journal of educational technology : journal of the Council for Educational Technology》2015,46(6):E30-E31

This book combines cultural models with practice‐based learning to develop a new theory of cultural learning. Drawing on insights from anthropology, it argues how collective and social cultures can emerge from an “engaged” learning process. The book opens a new window on human learning; however, you will probably find only parts of it of some interest or use. Mohammad Ali Salmani Nodoushan  相似文献   

Fuzzy sliding mode control design for a class of disturbed systems     

Bo Wang  Peng Shi  Hamid Reza Karimi 《Journal of The Franklin Institute》2014

This paper discusses the problem of the fuzzy sliding mode control for a class of disturbed systems. First, a fuzzy auxiliary controller is constructed based on a feedback signal not only to estimate the unknown control term, but also participates in the sliding mode control due to the fuzzy rule employed. Then, we extend our theory into the cases, where some kind of system information can not be obtained, for better use of our theoretical results in real engineering. Finally, some typical numerical examples are included to demonstrate the effectiveness and advantage of the designed sliding mode controller.  相似文献   

Adaptive output feedback neural network control of uncertain non-affine systems with unknown control direction     

Mohammad M. Arefi  Jafar Zarei  Hamid R. Karimi 《Journal of The Franklin Institute》2014

This paper deals with the problem of adaptive output feedback neural network controller design for a SISO non-affine nonlinear system. Since in practice all system states are not available in output measurement, an observer is designed to estimate these states. In comparison with the existing approaches, the current method does not require any information about the sign of control gain. In order to handle the unknown sign of the control direction, the Nussbaum-type function is utilized. In order to approximate the unknown nonlinear function, neural network is firstly exploited, and then to compensate the approximation error and external disturbance a robustifying term is employed. The proposed controller is designed based on strict-positive-real (SPR) Lyapunov stability theory to ensure the asymptotic stability of the closed-loop system. Finally, two simulation studies are presented to demonstrate the effectiveness of the developed scheme.  相似文献   

TSH Comparison Between Chemiluminescence (Architect) and Electrochemiluminescence (Cobas) Immunoassays: An Indian Population Perspective     

Rajarshi Sarkar 《Indian journal of clinical biochemistry : IJCB》2014,29(2):189-195

Although 3rd generation TSH assays are the most widely used immunoassays, credible comparison studies, specially involving Indian sub-populations are practically non-existent. To compare the TSH measurements between chemiluminescence (Architect) and electrochemiluminescence (Cobas) inmmunoassays in an urban ambulatory Indian population. 1,615 subjects were selected randomly from the usual laboratory workflow, their TSH measured in Architect and Cobas and the paired data thus generated were statistically analysed. TSH values of Cobas were observed to be higher than the Architect values by 28.7 %, with a significant proportional difference between the two, but majority of the Cobas values (above 90 %) were within the limits of agreement with Architect values. In situations where both the instruments are in use simultaneously, a standardization of the methods is imperative, in larger interest of the patient populace.  相似文献   

Engendering a culture of thinking in a culture of performativity: the challenge of mediating tensions in the Singaporean educational system     

Mohammad Akshir Ab Kadir 《Cambridge Journal of Education》2017,47(2):227-246

Among the major policies that have been implemented to ensure its continued success, Thinking Schools, Learning Nation (TSLN) has been described as the ‘big bang of educational reforms’ in Singapore. However, while the policy aims to develop critical thinkers in school leavers, the corporatisation of education in the shape of structures such as the school excellence model seems to be at odds with TSLN. This paper argues that these structures unwittingly engender a culture of performativity among schools, marginalising the central outcome of its initiative that entails developing a culture of thinking and thinkers. The tension is further exacerbated by the larger rationalities that have shaped Singapore and the pragmatic and instrumental philosophy which underpins its educational system. The tensions generated by the clash between intended (culture of thinking) and engendered culture (culture of performativity) present the challenge of mediation for the system on its path to realising TSLN.  相似文献   

H∞ dynamic observer-based fuzzy integral sliding mode control with input magnitude and rate constraints     

Zeinab Echreshavi  Mokhtar Shasadeghi  Mohammad Hassan Asemani 《Journal of The Franklin Institute》2021,358(1):575-605

This paper focuses on a systematic constrained fuzzy integral sliding mode controller design for a class of uncertain discrete-time nonlinear systems which can be represented as Takagi-Sugeno (T-S) fuzzy models. The contributions are to consider constraints on the control input amplitude and control input amplitude rate and to extend the existing pole-placement design technique for designing gain matrices of the fuzzy sliding surface. Moreover, a dynamic-gain observer along with ${\mathit{H}}_{\infty }$ performance is proposed for attenuating disturbance, which generalizes the existing results on the Proportional Observer (PO), the Proportional Integral Observer (PIO) and the dynamic observer (DO). Finally, the dynamic-observer-based constrained fuzzy integral sliding mode controller is designed. All the proposed design conditions are represented in terms of LMIs-based ones. The methods are studied for not only single-input single-output (SISO) but also multi-input multi-output (MIMO) systems. In the end, the proposed approaches are evaluated on practical and numerical systems to illustrate the superiority of the proposed control scheme.  相似文献