首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   3063篇
  免费   58篇
  国内免费   2篇
教育   2339篇
科学研究   157篇
各国文化   35篇
体育   289篇
文化理论   49篇
信息传播   254篇
  2023年   36篇
  2022年   55篇
  2021年   59篇
  2020年   113篇
  2019年   189篇
  2018年   249篇
  2017年   220篇
  2016年   199篇
  2015年   151篇
  2014年   157篇
  2013年   646篇
  2012年   128篇
  2011年   101篇
  2010年   95篇
  2009年   60篇
  2008年   80篇
  2007年   68篇
  2006年   40篇
  2005年   42篇
  2004年   51篇
  2003年   41篇
  2002年   39篇
  2001年   25篇
  2000年   33篇
  1999年   18篇
  1998年   21篇
  1997年   11篇
  1996年   25篇
  1995年   17篇
  1994年   17篇
  1993年   11篇
  1992年   9篇
  1991年   13篇
  1990年   13篇
  1989年   12篇
  1988年   10篇
  1987年   5篇
  1986年   8篇
  1985年   6篇
  1980年   6篇
  1979年   3篇
  1978年   2篇
  1977年   2篇
  1976年   6篇
  1975年   2篇
  1974年   3篇
  1973年   2篇
  1972年   2篇
  1970年   2篇
  1967年   3篇
排序方式: 共有3123条查询结果,搜索用时 15 毫秒
121.
122.
Isolation and enrichment of low-abundant particles are essential steps in many bio-analytical and clinical applications. In this work, the capability of an insulator-based dielectrophoresis (iDEP) device for the detection and stable capture of low abundant polystyrene particles and yeast cells was evaluated. Binary and tertiary mixtures of particles and cells were tested, where the low-abundant particles had concentration ratios on the order of 1:10 000 000 compared to the other particles present in the mixture. The results demonstrated successful and stable capture and enrichment of rare particles and cells (trapping efficiencies over 99%), where particles remained trapped in a stable manner for up to 4 min. A device with four reservoirs was employed for the separation and enrichment of rare particles, where the particles of interest were first selectively concentrated and then effectively directed to a side port for future collection and analysis. The present study demonstrates that simple iDEP devices have appropriate screening capacity and can be used for handling samples containing rare particles; achieving both enrichment and isolation of low-abundant particles and cells.  相似文献   
123.
Ball screens are one of the most frequently used tactical behaviour in elite basketball games. The aim of the present study was to identify their predictors of success related to time, space, players, and tasks performed. The sample was composed of 818 ball screens corresponding to 20 close games (mean differences in score of 3.1 ± 0.8 points) randomly selected from the playoff games of the Spanish Basketball League (2008–2011). Classification tree analysis (CHAID) was used to analyse which variable or combination of variables, better predicts effectiveness during ball screens. The main results allowed identifying interactions with dribbler actions after the screen and the orientation of the screen on the ball. The results showed no interaction with game quarter and quarter minute temporal-related variables in both analyses. The present findings allow improving coaches’ strategic plans that involve selecting the most appropriate offensive approach when performing ball screens.  相似文献   
124.
A motor skills assessment could be helpful in talent development by estimating essential perceptuo-motor skills of young players, which are considered requisite to develop excellent technical and tactical qualities. The Netherlands Table Tennis Association uses a motor skills assessment in their talent development programme consisting of eight items measuring perceptuo-motor skills specific to table tennis under varying conditions. This study aimed to investigate this assessment regarding its reproducibility, internal consistency, underlying dimensions and concurrent validity in 113 young table tennis players (6–10 years). Intraclass correlation coefficients of six test items met the criteria of 0.7 with coefficients of variation between 3% and 8%. Cronbach’s alpha valued 0.853 for internal consistency. The principal components analysis distinguished two conceptually meaningful factors: “ball control” and “gross motor function.” Concurrent validity analyses demonstrated moderate associations between the motor skills assessment’s results and national ranking; boys r = ?0.53 (< 0.001) and girls r = ?0.45 (= 0.015). In conclusion, this evaluation demonstrated six test items with acceptable reproducibility, good internal consistency and good prospects for validity. Two test items need revision to upgrade reproducibility. Since the motor skills assessment seems to be a reproducible, objective part of a talent development programme, more longitudinal studies are required to investigate its predictive validity.  相似文献   
125.

Objective

The aim of this study was to evaluate the concentrations of C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and the degree of homeostasis model assessment-insulin resistance (HOMA-IR) in patients with morbid obesity exposed to a three-week low-calorie diet and balneotherapy.

Methods

The study included 33 patients (25 females and 8 males; mean age 46 years) with body mass index (BMI) values of >40 kg/m2. Evaluations of CRP, IL-6, TNF-α, lipid profile, HOMA-IR, and fasting glucose were carried out before (baseline data) and three weeks after the treatment. The control group consisted of 20 healthy volunteers (15 females and 5 males) with a mean age of 39 years and BMI values of ≤24.9 kg/m2.

Results

In the blood of patients with morbid obesity we found significantly elevated levels of CRP, TNF-α, triglycerides, HOMA-IR and fasting glucose, but a decreased level of high density lipoprotein (HDL)-cholesterol, compared with the healthy individuals. The treatment resulted in about a 9.4% reduction in body weight from 122.5 to 111.0 kg and a significant decrease in the concentration of CRP, but no change in TNF-α or IL-6. HOMA-IR was significantly reduced.

Conclusion

The decrease in CRP level without changes in TNF-α or IL-6 concentrations after the low-calorie diet and balneological treatment, suggests that an essential amount of adipose tissue must be removed before proper adipocyte function is restored. The decrease in HOMA-IR indicates an improvement in insulin sensitivity, which is beneficial in obese patients.
  相似文献   
126.
In recent years, there has been a growing recognition of the fact that the proper management of information has to include concern for its preservation and future re-use. This ambition is particularly significant for geospatial data. The primary aim of this article is to define the European and Spanish frameworks for the preservation and reutilization of geographical information, with the ultimate goal of proposing an articulated, lifecycle-based data management model. With this, the intent is to shed some light on a complex, difficult and ever-evolving subject.

The article is divided into two main parts. The first part begins with a conceptual justification for geospatial data management and continues by synthesizing the current normative and technological framework for the preservation and reutilization of geographical information. Within this context, the implementation of Spatial Data Infrastructures (SDI) in Spain is evaluated. The second part begins with a case study from Spain that aims to identify different agents and flows that influence the lifecycle of geographical data, as well as the strengths and weaknesses found in each stage of the process under examination. Finally, the foregoing ideas are used in order to propose a SDI-related system for the management of geographical information.  相似文献   
127.
People still use documents in many everyday government processes. From tax payments to passport requests, citizens have to interact with low-interactivity information artifacts such as reports, maps and datasets, among many others. Despite efforts to improve information delivery in the public sector, effective information usage remains a critical topic of action and research. The user experience of government documents has rarely been assessed, despite them being regularly published and frequently used. Considering this, the two following research questions arise: 1) How can government documents be classified (or grouped) in terms of user experience? 2) How can the user experience of government documents be monitored over time in order to inform design decisions? Working with a public agency in Chile, we develop and test a classification and monitoring framework based on two online surveys (N?=?338 and N?=?298). We then propose a framework for understanding user experience of government documents in these three dimensions: interaction goal, volume of information and ease of understanding. Using a graphical representation to classify user experience provides greater visibility of the current status of information produced by a public organization. Furthermore, by monitoring the user experience of a government document at different times, organizations can understand the effect of their design decisions and improve their service quality by implementing user-centered processes.  相似文献   
128.
The combined effects of pH and temperature on red pigment production and fungal morphology were evaluated in a submerged culture of Penicillium purpurogenum GH2, using Czapek-Dox media with d-xylose as a carbon source. An experimental design with a factorial fix was used: three pH values (5, 7, and 9) and two temperature levels (24 and 34 °C) were evaluated. The highest production of red pigment (2.46 g/L) was reached with a pH value of 5 and a temperature of 24 °C. Biomass and red pigment production were not directly associated. This study demonstrates that P. purpurogenum GH2 produces a pigment of potential interest to the food industry. It also shows the feasibility of producing and obtaining natural water-soluble pigments for potential use in food industries. A strong combined effect (p<0.05) of pH and temperature was associated with maximal red pigment production (2.46 g/L).  相似文献   
129.

Objective  

The influence of hormone replacement therapy (HRT) on hemostasis processes depends on the type of hormone, the combination of doses, the time of taking HRT, and the route of administration (oral, transdermal, implanted). The aim of the current study was to assess some parameters of coagulation, especially tissue factor pathway inhibitor (TFPI) and tissue factor (TF) in postmenopausal women using oral or transdermal HRT.  相似文献   
130.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号