George Andrew Olah     

Ripudaman Malhotra  Thomas Mathew  G K Surya Prakash 《Resonance》2017,22(12):1111-1153

Hungarian born American chemist, George Andrew Olah was a prolific researcher. The central theme of his career was the pursuit of structure and mechanisms in chemistry, particularly focused on electron-deficient intermediates. He leaves behind a large body of work comprising almost 1500 papers and twenty books for the scientific community. Some selected works have been published in three aptly entitled volumes, Across Conventional Lines.There is no way to capture the many contributions of Olah in a short essay. For this appreciation, we have chosen to high-light some of those contributions that to our mind represent a significant advance to the state of knowledge.  相似文献   

Serum gamma glutamyl transpeptidase in breast cancer     

Shashi Seth  Bina Ravi  H. S. Randhawa  Neelam Chillar  Harbans Lal 《Indian journal of clinical biochemistry : IJCB》1996,11(1):49-51

Gamma-glutamyl transpeptidase (gamma-GT) levels were estimated in the sera of patients with breast cancer and compared with those of benign breast diseases and healthy controls. Serum gamma-GT levels were found to be significantly increased in patients with breast cancer compared to the controls as well as benign breast diseases. The rise however, was nearly same in all the patients irrespective of histopathology of cancer but was directly related to tumour mass. After mastectomy the levels remained higher upto 3 months. In patients with cancer the rise in serum gamma-GT was significantly higher as compared to those with benign breast diseases. Although gamma-GT is an index of liver diseases, its high level in breast carcinoma suggests the release of the membrane bound constituents from different tissues even in carcinoma.  相似文献   

Comparative genomics reveal shared genomic changes in syngnathid fishes and signatures of genetic convergence with placental mammals     

Yan-Hong Zhang  Vydianathan Ravi  Geng Qin  He Dai  Hui-Xian Zhang  Feng-Ming Han  Xin Wang  Yu-Hong Liu  Jian-Ping Yin  Liang-Min Huang  Byrappa Venkatesh  Qiang Lin 《国家科学评论(英文版)》2020,7(6):964

Syngnathids (seahorses, pipefishes and seadragons) exhibit an array of morphological innovations including loss of pelvic fins, a toothless tubular mouth and male pregnancy. They comprise two subfamilies: Syngnathinae and Nerophinae. Genomes of three Syngnathinae members have been analyzed previously. In this study, we have sequenced the genome of a Nerophinae member, the Manado pipefish (Microphis manadensis), which has a semi-enclosed brood pouch. Comparative genomic analysis revealed that the molecular evolutionary rate of the four syngnathids is higher than that of other teleosts. The loss of all but one P/Q-rich SCPP gene in the syngnathids suggests a role for the lost genes in dentin and enameloid formation in teleosts. Genome-wide comparison identified a set of 118 genes with parallel identical amino acid substitutions in syngnathids and placental mammals. Association of some of these genes with placental and embryonic development in mammals suggests a role for them in syngnathid pregnancy.  相似文献   

!Pressure melting and skating     

Ravi Divakaran  G. S. Ranganath  Mohan Devadas  J. Chandrasekhar  Rajaram Nityananda 《Resonance》1996,1(5):71-78

In this section of Resonance, we invite readers to pose questions likely to be raised in a classroom situation. We may suggest strategies for dealing with them, or invite responses, or both. “Classroom” is equally a forum for raising broader issues and sharing personal experiences and viewpoints on matters related to teaching and learning science.  相似文献   

After Virtue: A Quest for Moral Objectivity*     

Madhu Suri Prakash  Mark Weinstein 《Educational theory》1982,32(1):35-44

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Hypoadiponectinemia in Obesity: Association with Insulin Resistance     

Jai Prakash  Balraj Mittal  Shally Awasthi  C. G. Agarwal  Neena Srivastava 《Indian journal of clinical biochemistry : IJCB》2013,28(2):158-163

Obesity is risk factor for insulin resistance, diabetes, and other chronic diseases. Adiponectin, an adipose-specific protein with antiatherogenic and antiinflammatory effects, were found to be associated with obesity, type 2 diabetes, and insulin resistance. Our aim to identify possible relationships between circulating adiponectin and obesity as well as obesity related phenotypes. A total of 642, obese and non-obese individuals were included in this cross-sectional study. Hormone and glucose levels were estimated using standard protocols. The adiponectin levels showed a significant decrease with increasing quartiles of insulin resistance index. Subjects in lowest quartile of adiponectin level had a significantly higher risk than those in the highest quartile, with higher body mass index, waist circumference, blood pressure, percentage body fat, fat mass, fasting insulin, insulin resistance index, total cholesterol (p < 0.001), low density lipoprotein–cholesterol (p = 0.001), very low density lipoprotein–cholesterol (p = 0.002), and Triglyceride (p = 0.002). The present study indicates that adiponectin is significantly associated with obesity, insulin resistance and other obesity related phenotypes.  相似文献   

Influence of group formation choices on academic performance   总被引：1，自引：1，他引：0  

Ravi Seethamraju  Mark Borman 《Assessment & Evaluation in Higher Education》2009,34(1):31-40

With its multidisciplinary and applied foci, team‐working skills are seen as especially critical in business courses in general and in business information systems courses in particular, and are specifically incorporated into desired graduate attributes by many universities. Past research has focused on the benefits of group working but little work has been conducted to examine the relative contribution of group formation choices on academic performance. This paper reports on a study that develops and validates a data‐collection instrument and identifies four underlying factors that influence formation of groups: convenience, social cohesion, task management and technical skills/knowledge. The results thus suggest that academic performance is influenced by the skills and knowledge of individual members, potential social cohesion among the group members and the task management ability considered at the group formation stage. The study notes that while how a group is formed influences ultimate academic performance, how the group operates is also an important factor.  相似文献   

Study of oxidative stress in obsessive compulsive disorder in response to treatment with Fluoxetine     

Sutirtha Chakraborty  Anindya Dasgupta  Harendra Nath Das  Om Prakash Singh  Asok Kumar Mandal  Nikhiles Mandal 《Indian journal of clinical biochemistry : IJCB》2009,24(2):194-197

Oxidative stress has been found to play important role in several neuropsychiatric diseases including Obsessive Compulsive Disorder. A longitudinal case control study was conducted to evaluate the oxidative stress in 30 newly diagnosed obsessive compulsive disorder patients and same number of control patients. Serum thiobarbituric acid reacting substances, plasma ascorbate were assessed to evaluate oxidative stress and Yale Brown obsessive compulsive scale for disease severity before and after treatment with Fluoxetine at the average dosage of 40 mg/day. Improvement in Yale Brown obsessive compulsive scale score by about 43% after 12 weeks treatment was associated with significantly decreased thiobarbituric acid reacting substances and increased plasma ascorbate values (p < 0.05). The newly diagnosed obsessive compulsive disorder patients had higher serum thiobarbituric acid reacting substances as well as a lower plasma ascorbate levels than the control population. Thus, the present study suggested a significant role of oxidative stress in obsessive compulsive disorder and showed that a successful treatment with Fluoxetine not only improves the clinical scenario but also reduces the oxidative stress that may further improve the prognosis of the disease.  相似文献   

Mutually supportive or trade-offs: An analysis of competitive priorities in the emerging economy of India     

Ravi Kathuria  Narinder Nath Kathuria  Abhishek Kathuria 《The Journal of High Technology Management Research》2018,29(2):227-236

To refine the theories of operations strategy, we need research from all different situational contexts, including different countries—both developing and developed. There have been many studies, including some replications, done in various parts of the world to further the debate on whether competitive priorities are mutually supportive or if they present potential trade-offs, but hardly any from a rapidly growing economy, such as India. This study is a significant attempt in that direction. After a thorough review of the literature, a set of hypotheses is introduced to test whether Indian manufacturers view competitive priorities as mutually supportive or trade-offs. The data from over 150 high-ranking individuals from over 75 manufacturers in India is used to test the hypotheses by way of cluster analysis and ANOVA. The resultant taxonomy reveals patterns that uniquely represent Indian manufacturers' view of the competitive priorities, namely quality, flexibility, delivery and price. The study findings have significant managerial implications, both for India and other developing as well as developed economies. The taxonomy will serve to gauge India's manufacturers' role in the world. From a researcher's perspective, this study makes a significant contribution to theory development, furthers our understanding of the strategic role of operations, moves forward the ongoing debate on the topic of trade-offs or complementarity, and paves the way for future studies in this topical area.  相似文献   

Urinary protein thiols in different grades of proteinuria     

Mungli Prakash  Jeevan K. Shetty  Sambit Dash  Bijay K. Barik  Abhirup Sarkar  Sharanabasappa M. Awanti  Ravindra Prabhu 《Indian journal of clinical biochemistry : IJCB》2008,23(4):404-406

Total thiol status of plasma, especially thiol groups over protein contributes maximum to the plasma antioxidant status of the body. Serum protein thiols were found to be decreased in various disease conditions including chronic renal failure patients. Only few studies determined the levels of urinary protein thiols in disease conditions. The current study was designed to know the levels of urinary protein thiols in patients with different grades of proteinuria. The study was conducted on urine of 40 healthy controls and 61 cases with proteinuria. Based on proteinuria cases were further divided into two groups; group I - microproteinuria (150–300 mg protein/d), 32 cases, group II - frank proteinuria (>300 mg protein/d), 29 cases. Urinary thiol levels were determined by spectrophotometric method using dithionitrobenzoic acid. A significant decrease (p<0.01) in urinary thiol in group I and group II cases was observed in present study and this decrease was associated with proteinuria.  相似文献