全文获取类型
收费全文 | 3004篇 |
免费 | 33篇 |
国内免费 | 66篇 |
专业分类
教育 | 2270篇 |
科学研究 | 366篇 |
各国文化 | 4篇 |
体育 | 219篇 |
综合类 | 191篇 |
文化理论 | 5篇 |
信息传播 | 48篇 |
出版年
2024年 | 1篇 |
2023年 | 7篇 |
2022年 | 4篇 |
2021年 | 34篇 |
2020年 | 26篇 |
2019年 | 20篇 |
2018年 | 9篇 |
2017年 | 12篇 |
2016年 | 24篇 |
2015年 | 50篇 |
2014年 | 185篇 |
2013年 | 158篇 |
2012年 | 214篇 |
2011年 | 230篇 |
2010年 | 175篇 |
2009年 | 171篇 |
2008年 | 201篇 |
2007年 | 254篇 |
2006年 | 241篇 |
2005年 | 210篇 |
2004年 | 157篇 |
2003年 | 149篇 |
2002年 | 109篇 |
2001年 | 101篇 |
2000年 | 86篇 |
1999年 | 52篇 |
1998年 | 28篇 |
1997年 | 40篇 |
1996年 | 41篇 |
1995年 | 22篇 |
1994年 | 18篇 |
1993年 | 18篇 |
1992年 | 11篇 |
1991年 | 12篇 |
1990年 | 13篇 |
1989年 | 5篇 |
1988年 | 1篇 |
1986年 | 1篇 |
1985年 | 2篇 |
1984年 | 1篇 |
1983年 | 1篇 |
1982年 | 4篇 |
1981年 | 1篇 |
1980年 | 1篇 |
1979年 | 1篇 |
1978年 | 1篇 |
1977年 | 1篇 |
排序方式: 共有3103条查询结果,搜索用时 15 毫秒
71.
不同品种黄瓜幼苗光合机构对盐胁迫的响应 总被引:26,自引:0,他引:26
研究了盐胁迫(0、25、50mmol/L)对不同品种黄瓜幼苗生长、光合作用和叶绿素荧光的影响.结果表明,盐胁迫,尤其是高浓度NaCl(50mmol/L)的胁迫,显著降低黄瓜幼苗生长量、叶绿素含量、光系统Ⅱ光合电子传递量子效率(φPSⅡ)、净光合速率(Pn)、气孔导度(Gs)以及气孔限制值(Ls),同时显著提高叶片相对电导率、丙二醛、脯氨酸含量和细胞间CO2浓度(Ci),光系统Ⅱ的光化学效率(Fv/Fm)变化不大.盐胁迫对耐盐黄瓜‘津研4号’幼苗生长的影响小于盐敏感黄瓜‘津绿4号’,这可能与耐盐黄瓜在盐胁迫下较高的净光合速率、光系统Ⅱ光合电子传递量子效率和较低的丙二醛(MDA)含量、相对电导率有关。 相似文献
72.
G. N. Raval L. J. Parekh D. D. Patel F. P. Jha R. N. Sainger P. S. Patel 《Indian journal of clinical biochemistry : IJCB》2004,19(2):60-71
Sialic acid, the end moieties of the carbohydrate chains are biologically important and essential for functions of glycoconjugates
and are reported to be altered in cancer patients. Two hundred and twenty five breast cancer (BC) patients, 100 patients with
benign breast disease (BBD) and 100 healthy females (controls) were enrolled for the study. Eight hundred and twenty four
follow-up samples of 225 breast carcinoma patients were also evaluated. The association of sialic acid forms, sialyltransferase
and α-2–6 sialoproteins levels with presence and extent as well as prognosis of breast carcinoma was studied. Serum sialic
acid forms and sialyltransferase revealed significantly elevated levels among untreated breast cancer patients as compared
to the controls, patients with BBD as well as cancer patients in remission. Non-responders showed comparable levels of the
markers with those found in breast cancer patients at the time of diagnosis. Higher levels of sialic acid forms at diagnosis
were associated with poor prognosis. A positive correlation between serum levels of different forms of sialic acids and extent
of malignant disease was observed. The changes in serum proteins with terminal α-2–6 sialic acid correlated well with alterations
in the levels of sialic acid forms and sialyltransferase. Malignant tissues showed elevated levels of sialic acid and sialyltransferase
as compared to surrounding normal tissues.
The results suggested potential utility of these markers in evaluation of clinical outcome. 相似文献
73.
6RA70在直流传动系统中的应用 总被引:2,自引:0,他引:2
介绍SIMOREG 6RA70的特点,对系统各主要模块的功能进行了论述,介绍了它的工作原理,系统具有安全、可靠等特点。 相似文献
74.
Lakshmi Lavanya Reddy Swarup A. V. Shah Alpa J. Dherai Chandrashekhar K. Ponde Tester F. Ashavaid 《Indian journal of clinical biochemistry : IJCB》2016,31(1):87-92
Acute coronary syndrome (ACS) is a term for a range of clinical signs and symptoms suggestive of myocardial ischemia. It results in functional and structural changes and ultimately releasing protein from injured cardiomyocytes. These cardiac markers play a major role in diagnosis and prognosis of ACS. This study aims to assess the efficacy of heart type fatty acid binding protein (h-FABP) as a marker for ACS along with the routinely used hs-TropT. In our observational study, plasma h-FABP (cut-off 6.32 ng/ml) and routinely done hs-Trop T (cutoff 0.1 and 0.014 ng/ml) were estimated by immunometric laboratory assays in 88 patients with acute chest pain. Based on the clinical and laboratory test findings the patients were grouped into ACS (n = 41) and non-ACS (n = 47). The diagnostic sensitivity, specificity, NPV, PPV and ROC curve at 95 % CI were determined. Sensitivity of hs-TropT (0.1 ng/ml), hs-TropT (0.014 ng/ml) and h-FABP were 53, 86 and 78 % respectively and specificity for the same were 98, 73 and 70 % respectively. Sensitivity, specificity and NPV calculated for a cut-off combination of hs-TropT 0.014 ng/ml and h-FABP was 100, 51 and 100 % respectively. These results were substantiated by ROC analysis. Measurement of plasma h-FABP and hs-TropT together on admission appears to be more precise predictor of ACS rather than either hs-Trop T or h-FABP. 相似文献
75.
BackgroundDiabetes is a metabolic disorder caused by defects in insulin production and activity. During disease progression, changes in lipid peroxidation cause structural modifications via production of free radicals. Fangchinoline is a well-known alkaloid present in Stephaniae tetrandrine S. Moore, which has demonstrated antioxidant, anticancer, and anti-inflammatory activities.ResultsThe present study analyzed the anti-diabetic and antioxidant effects of fangchinoline in male rats with streptozotocin-induced diabetes. Rats were divided into the following groups: normal control, diabetic, diabetic + fangchinoline 100 mg/kg, diabetic + fangchinoline 200 mg/kg and diabetic + glibenclamide 600 µg/kg. The treatment was administered orally for 45 consecutive days. Lipid peroxidation was substantially increased by >50% in the serum, as well as the liver, kidney, and heart tissues of diabetic rats. However, fangchinoline supplementation significantly reduced lipid peroxidation to near normal levels. Reactive oxygen species levels were substantially increased by >500% in the serum, as well as the liver, kidney, and heart tissues of diabetic rats. Fangchinoline supplementation reduced reactive oxygen species to near normal levels. Fangchinoline supplementation significantly improved superoxide dismutase, glutathione peroxidase, catalase, and reduced glutathione levels in diabetic rats. Total hexoses, sialic acid, hexosamines, and fucose were increased in diabetic rats, whereas fangchinoline supplementation significantly reduced these total hexoses, sialic acid, hexosamines, and fucose to near normal levelsConclusionsSupplementation with fangchinoline led to significant attenuation of the levels of lipid peroxidation, ROS, and glycoprotein components such as total hexoses, hexosamines, sialic acid, and fucose, while improving antioxidant marker levels.How to cite: Xia J, Huang W, Zhou F. Effect of fangchinoline on oxidant status in male albino rats with streptozotocin-induced diabetes. Electron J Biotechnol 2021;53. https://doi.org/10.1016/j.ejbt.2021.07.005 相似文献
76.
Response surface methodology (RSM) was used to optimize the fermentation medium for enhancing pyruvic acid production by Torulopsis glabrata TP19. In the first step of optimization, with Plackett-Burman design, ammonium sulfate, glucose and nicotinic acid were found to be the important factors affecting pyruvic acid production significantly. In the second step, a 23 full factorial central composite design and RSM were applied to determine the optimal concentration of each significant variable. A second-order polynomial was determined by the multiple regression analysis of the experimental data. The optimum values for the critical components were obtained as follows: ammonium sulfate 0.7498 (10.75 g/L), glucose 0.9383 (109.38 g/L) and nicotinic acid 0.3633 (7.86 mg/L) with a predicted value of maximum pyruvic acid production of 42.2 g/L. Under the optimal conditions, the practical pyruvic acid production was 42.4 g/L. The determination coefficient (R^2) was 0.9483, which ensures adequate credibility of the model. By scaling up fermentation from flask to jar fermentor, we obtained promising results. 相似文献
77.
78.
79.
维希政府是二战时期存在于法国南部的临时性政权。政府各主要领导人在对德外交方面各自推行自己认为行之有效的外交方略。但由于外交主动权的丧失,这些外交方略大都没有达到推行人的预期目的,甚至出现外交成效与预期目的逆向发展的局面。 相似文献
80.