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61.
This study was aimed to elucidate whether there is significant relationship between the lower calyceal anatomy and stone evacuation following extracorporeal shock wave lithotripsy(ESWL). From April 1995 to November 1999, 145 patients with lower caliceal stones underwent ESWL with Storz Modulith SL20 lithotriptor. The pelvicalyecal angle, lower pole infundibular length and width, and lower pole calyceal pattern of the stone-bearing calyx were measured on pre-ESWL intravenous urograms. Abdominal plain film and ultrasonography taken of all patients at the 3-month followup showed that the overall stone-free rate was 65% after 3 months. The stone-free rate was significantly correlated to the radiographic anatomical factor, 94% in patients with a pelvicalyceal angle of 90 degrees or greater, 57% in those with less than 90 degrees pelvicalyceal angle; 80% in those with infundibular length of 30 mm or less, 59% in those with infundibular length greater than 30 mm; 73% in those with infundibular width greater than 4 mm, 48% in those with infundibular width of 4 mm or less; 85% in those with a simple calyceal pattern and 41% in those with a complex one. These findings suggest that the 4 radiographic anatomical factors of the lower pole calyx (pelvicalyceal angle, infundibular length and width and calyceal pattern) play an important role in stone evacuation after ESWL. Pelvicalyceal angle of 90 degrees or greater, infundibular length of 30 mm or less and width greater than 4 mm, and simple calyceal pattern are respectively noted to relate to an improved stone-free status. In contrast, an acute pelvicalyceal angle, long infundibular length and narrow infundibular width and complex calyceal pattern are individually unfavorable factors for stone emptying following ESWL.  相似文献   
62.
Modified low density lipoproteins (LDL), including their oxidized forms, have been widely implicated in the etiology of atherosclerosis and concomitant cardiovascular disease (CVD) in chronic renal failure (CRF). The nature of events that lead to oxidative changes in LDL proteins are not clearly understood. Thus, patients suffering from CRF were grouped into mild, moderate and severe categories based on their blood urea and serum creatinine levels. Progression of CRF was accompanied not only with gradual increase in serum malondialdehyde (MDA) but also parallel increase in conjugated diene and MDA levels in LDL fractions separated from serum. Serum superoxide dismutase (SOD) activity was concurrently found to decrease, along with a decrease in high-density lipoprotein (HDL) cholesterol, during the progression of CRF. Gradual increase in the appearance of LDL oxidation products seems to accompany progressive manifestation of CRF. The results presented suggest that determination of serum MDA and SOD levels may enhance the diagnostic significance of the study of lipid profile in determining the risk for cardio vascular disease in CRF.  相似文献   
63.
自由基清除剂在运动后对血浆LpO和肾组织结构的影响   总被引:2,自引:0,他引:2  
运动后1小时测定SD鼠血浆丙二醛(MDA),并观察肾组织超微结构,发现血浆MDA上升至13.325nmol/ml,肾上皮足突广泛融合(p≈0.05)、线粒体肿胀破裂。经用VE和VC血浆MDA上升值下降至11.868nmul/ml(p<0.05),加用GSH后血浆MDA上升值下降至9.592nmol/ml(p<0.05);肾形态变化减弱、足突变化(p>0.05)、线粒体完整。提示合用GSH、VE和VC可降低血浆MDA上升值,保护肾脏。  相似文献   
64.
90~100日龄 Wisten雄性大 21只,随机分成 3 组,并在同样条件下饲养,其中一组在安静条件下处死,另一组在力竭性游泳2小时后处死,第三组在力竭性游泳后立即处死.然后检测它们的血乳酸、血肌酐、血尿酸水平,结果显示力竭性运动后血乳酸增多以及肾血流量和肾过滤率下降是血尿酸水平上升的主要原因。  相似文献   
65.
目的:探讨口服吡喹酮的副反应及防治。方法:对口服吡喹酮致急性肾功衰的个案进行回顾性分析。结果:确认吡喹酮致急性肾功衰。结论:吡喹酮有导致肾功能损害的副作用。  相似文献   
66.
It is of great importance to investigate an effective and reliable medication against chronic renal failure (CRF)-related erectile dysfunction (ED), which aims to improve patients’ life qualities. The concentrations of cyclic guanosine monophosphate (cGMP) in the corpus cavernosal smooth muscle of both CRF and control rabbits were measured. The effects of various concentrations of tadalafil, papaverine, and sodium nitroprusside on the relaxation responses of corpus cavernosal smooth muscle pre-contracted with phenylephrine in CRF rabbits were observed. There was significant difference in the concentration of cGMP between CRF and control rabbits (P<0.01). Tadalafil had the greatest impacts on CRF rabbits when given the same concentration of papaverine or sodium nitroprusside and particularly significant differences were identified under the concentration levels of 10−5 and 10−4 mol/L (P<0.01). The results suggest that the cGMP concentrations of the corpus cavernosum had been greatly reduced in CRF rabbits compared with control rabbits and that tadalafil may be an ideal medication for use in the treatment of CRF-related ED.  相似文献   
67.
目的:探讨不同强度运动对青春期肥胖大鼠肝肾功能的影响。方法:建模7周后,选取喂食高脂饲料的肥胖大鼠24只,随机分为4组,每组6只,分别为安静对照组(Oc)、低强度运动组(OL)、中强度运动组(OM)、高强度运动组(OH)。OL、OM、oH分别以15-18m/min、21-25m/min和28-32m/min的强度运动,坡度均为0。,lh/天,5次/周,共干预8周。干预后麻醉大鼠采集血液,测定血浆蛋白以及肝肾功能相关指标。结果:8周运动干预后,大鼠体重、内脏脂肪量及体脂率运动组较对照组显著降低(P〈O.01);内脏脂肪量及体脂率0M、0H组显著低于OL组(P〈O.05、P〈O.01);血白蛋白OH组高于0c组(P〈0.01)。血尿素氮与血肌酐各组之间无明显差异(P〉o.05)。结论:实施8周不同强度运动干预后,使青春期肥胖大鼠体重、内脏脂肪量和体脂率明显降低,随着运动强度的增加,调节效果更明显。该运动干预能有效调节血浆蛋白与肝肾功能,但不同运动强度之间无明显差别。  相似文献   
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