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991.
992.
Motives to patent: Empirical evidence from Germany 总被引:4,自引:0,他引:4
Against the background of the patent upsurge, we first analyse the role of patenting and alternative instruments to protect intellectual property, based on a sample of German companies active in patenting. In a second step, we investigate the motives to patent, considering sector and company size effects. We find that company size matters, both for the importance of instruments and the motives to patent. Especially important are the new strategic motives to patent, like using patents to improve a company's own position in negotiations with partners, licensees and the financial sector, or to use patents as incentives for R&D personnel or performance indicators—these correlate positively with company size. We derive some possible challenges for future patent policies from these insights. 相似文献
993.
跨国公司R&D全球化研究的热点与展望 总被引:6,自引:0,他引:6
跨国公司R&D全球化的影响因素和海外R&D区位选择、跨国公司R&D全球化的动因、R&D机构的组织模式和海外子公司的责任分配、跨国公司海外R&D机构与知识溢出效应是当前西方国家对跨国公司R&D全球化研究的四个热点问题,在对其加以详细论述的基础上对今后的研究方向进行了展望。 相似文献
994.
分析论述了宝鸡装备制造业具有门类较全;产业优势与规模优势较大;速度高、贡献大;机床制造业突出的特点。同时也存在着产品技术含量低、产业链短、信息化程度低、营运系统不合理等问题。提出了解决这些问题的主要对策有:打造企业航母、增加R&D投入、重组营运系统、拉长产业链、进军国际市场、培育驰名品牌。 相似文献
995.
2015年12月,国务院发布了《关于新形势下加快知识产权强国建设的若干意见》,正式提出"知识产权强国"战略,以主动姿态谋求中国知识产权事业的转型发展。中国知识产权战略要从被动转向主动,必须采取弯道超车的策略,需要重点推进以创业为主的知识产权创造与经营、以全球化众包为特色的知识产权管理、以跨国技术并购为途径的知识产权国际化三方面工作。 相似文献
996.
There have been many previous studies exploring the relationship between R&D performance and firm size; however, to our knowledge, this issue has never been examined in terms of R&D output elasticity. This paper therefore sets out to re-examine the relationship of the two variables using R&D output elasticity as a measure of R&D performance. A total of 126 manufacturing firms, listed on the Taiwan Stock Exchange over the period from 1994 to 2000, are taken as the analytical sample. One practical consideration for choosing these particular firms is the relative abundance of data available for the variables for a longitudinal investigation. The estimates suggest that there is an approximating ‘U-type’ relationship between R&D productivity and firm size. This finding suggests that both large and small firms have higher R&D productivity, and even when the sample is divided into the high-tech and traditional sectors, such a finding still holds. Therefore, in contrast to the prior studies, this study shows that size offers advantage in R&D performance. 相似文献
997.
BackgroundPhospholipase D (PLD) is used as the biocatalyst for phosphatidylserine (PS) production. In general, PLD was expressed in insoluble form in Escherichia coli. High-level soluble expression of PLD with high activity in E. coli is very important for industrial production of PLD.ResultsStreptomyces chromofuscus PLD coding gene was codon-optimized, cloned without signal peptide, and expressed in E. coli. The optimal recombinant E. coli pET-28a+PLD/BL21(DE3) was constructed with pET-28a without His-tag. The highest PLD activity reached 104.28 ± 2.67 U/mL in a 250-mL shake flask after systematical optimization. The highest PLD activity elevated to 122.94 ± 1.49 U/mL by feeding lactose and inducing at 20°C after scaling up to a 5.0-L fermenter. Substituting the mixed carbon source with 1.0 % (w/v) of cheap dextrin and adding a feeding medium could still attain a PLD activity of 105.81 ± 2.72 U/mL in a 5.0-L fermenter. Fish peptone from the waste of fish processing and dextrin from the starch are both very cheap, which were found to benefit the soluble PLD expression.ConclusionsAfter combinatorial optimization, the high-level soluble expression of PLD was fulfilled in E. coli. The high PLD activity along with cheap medium obtained at the fermenter level can completely meet the requirements of industrial production of PLD.How to cite: Wu R, Cao J, Liu F, et al. High-level soluble expression of phospholipase D from Streptomyces chromofuscus in Escherichia coli by combinatorial optimization. Electron J Biotechnol 2021;50.https://doi.org/10.1016/j.ejbt.2020.12.002 相似文献
998.
Emre Özçelik 《Research Policy》2004,33(3):409-424
We examine the determinants of export performance of firms in the Turkish manufacturing industry. Prominent differences show up between innovator and non-innovator firms in terms of the impacts of such variables as firm size, advertisement intensities, ownership structures, and composition of employees. Importance of innovations and R&D activities, conduciveness of capital intensity, and insignificance of the real wage are meaningful as far as a rational international competition policy is concerned. Results are suggestive of a technology-oriented and capital-formative development path, if Turkey is to come up with the international competitive standards. 相似文献
999.
Two new species of bamboo, Dendrocalamus ovatus Xia et Chia and D.
textilis Xia, Chia et C. Y. Xia, collected from southwestern China aredescribed. 相似文献
1000.
中国基础研究经费占R&D经费的比例多大为宜 总被引:6,自引:0,他引:6
基于各国经验,特别是美国50年来的相关数据,提出和论证了关于基础研究经费占R&D经费比例问题的三个假说。把这三个假说与中国的实际相结合,预测了2002~2020年中国基础研究经费占R&D经费的比例及经费的资助结构和执行结构,其中,全国基础研究经费占R&D经费的比例,到2010年为7. 5%, 2020年为10 5%。 相似文献