Protective influence of vitamin E on the antioxidant defence system in the whole blood and liver of normal and alloxan-induced diabetic rats     

J. O. Olanlokun 《Indian journal of clinical biochemistry : IJCB》2008,23(1):62-66

The effect of oral administration of vitamin E for twenty-eight consecutive days on blood glucose, reduced glutathione levels, antioxidant enzymes (superoxide dismutase and catalase activities), and levels of malondialdehyde (as an index of free radical-mediated lipid peroxidation) was observed in the whole blood and liver of normal and alloxan-induced diabetic rats. It was found that oral administration of vitamin E significantly (p<0.05) lowered the blood glucose level and increased the body weight of the diabetic rats. The activities of superoxide dismutase and levels of reduced glutathione increased significantly (p<0.05) while the level of lipid peroxidation decreased.  相似文献   

傅立叶变换红外光谱对人体结石的研究     

李伟  童义平 《韩山师范学院学报》1999,20(2):75-78

本文用傅立叶变换红外光谱法研究了人体中各不同器官产生的结石（尿结石、胆结石）的成份。结果表明：傅立叶变换红外光谱法可方便地确认出人体结石中的羟磷灰石（尿结石）和胆红素钙、胆固醇及胆酸类物质（胆结石）。  相似文献   

Protective Effect of Emblica officinalis Against Alcohol-Induced Hepatic Injury by Ameliorating Oxidative Stress in Rats     

Damodara Reddy V  Padmavathi P  Gopi S  Paramahamsa M  Varadacharyulu NCh 《Indian journal of clinical biochemistry : IJCB》2010,25(4):419-424

The effect of Emblica officinalis fruit extract (EFE) against alcohol-induced hepatic damage in rats was investigated in the present study. In vitro studies showed that EFE possesses antioxidant as well nitric oxide (NO) scavenging activity. In vivo administration of alcohol (5 g/kg b.wt/day) for 60 days resulted increased liver lipid peroxidation, protein carbonyls, nitrite plus nitrate levels. Alcohol administration also significantly lowers the activities of superoxide dismutase, catalase, glutathione peroxidase, glutathione S-transferase and reduced glutathione as compared with control rats. Administration of EFE (250 mg/kg body weight) to alcoholic rats significantly brought the plasma enzymes towards near normal level and also significantly reduced the levels of lipid peroxidation, protein carbonyls and restored the enzymic and non-enzymatic antioxidants level. This observation was supplemented by histopathological examination in liver. Our data indicate that the tannoid, flavonoid and NO scavenging compounds present in EFE may offer protection against free radical mediated oxidative stress in rat hepatocytes of animals with alcohol-induced liver injury.  相似文献   

纳米酶：结合天然酶和人工催化的力量          下载免费PDF全文

杜鹏  高利增  焦健  范克龙  阎锡蕴 《中国科学院院刊》2024,39(5):809-820

纳米酶代表了一类新型人工酶和生物催化剂,打破了无机与有机生命的界限。它既有纳米材料的理化特性,也有独特的类酶催化活性。同时,这些理化特性有可能会调控催化活性,使得纳米酶跟天然酶、传统的模拟酶和化学催化剂区别开来。纳米酶有比较好的稳定性、耐高温、低温、耐酸碱、活性可调且多功能,目前受到了广泛关注,在生物医药、环境治理、绿色农业、新能源等领域展现出巨大的应用前景,并初步形成了相应的学科框架。为了更好地推动纳米酶的发展,拓展对纳米酶的认识,文章回顾了纳米酶发现,分析凝练了纳米酶的学科特点及其结构,综述了纳米酶的应用,并展望了未来的发展趋势。  相似文献   

Cell-in-cell phenomenon in urinary sediment: a case report     

Carlos Martínez-Figueroa  Karen Corts-Sarabia  Jos Antonio Tesser Poloni  Enrique Alejandro Molina-Avilez  Luis A. Palaoro  Amalia Vences-Velzquez 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2022,32(2)

The internalization of apoptotic cells by non-phagocytic cells has been observed in different tissues and could be an important mechanism for the elimination of dying cells. Here, we describe a probable event of phagocytosis of apoptotic cells mediated by urothelial cells in urinary sediment. A 90-years-old male patient was admitted unconscious to the hospital, visible signs included: pale skin and dry mucous membranes, presumptively diagnosed as dehydration. Blood test revealed anaemia (haemoglobin 130 g/L) and hyperglycaemia (glucose 7.8 mmol/L), urinalysis showed a picture of urinary tract infection (leukocyturia and bacteriuria). The microscopic analysis of urinary sediment revealed the presence of urothelial cells and leukocytes internalized in urothelial cells. Anti-CD68 (membrane marker of macrophages) was tested by immunocytochemistry and a negative result was observed. Based on the findings phagocytosis of apoptotic cells mediated by urothelial cells was identified. This phenomenon can be observed in urinary sediment and should not be confused with a neoplastic process since it is a physiological event of cell elimination.  相似文献   

冷激诱导耐冷性过程中小麦幼苗抗氧化酶的变化     

郭丽红  王定康  王德斌  陈雪  程威  陈善娜 《昆明师范高等专科学校学报》2007,29(4):71-74

采用小麦幼苗为材料，研究了冷激诱导抗冷性过程中超氧化物歧化酶（SOD），过氧化氢酶（CAT），抗坏血酸专一性过氧化物酶（APX）、愈创木酚过氧化物酶（GPX）四种抗氧化酶活性的变化，结果发现冷激可以提高SOD，CAT，APX，GPX四种抗氧化酶的活性，表明冷激诱导的抗冷性与SOD，CAT，APX，GPX四种抗氧化酶活性增加有关，暗示SOD，CAT，APX，GPX四种抗氧化酶在冷激诱导小麦幼苗抗冷性的形成过程中起重要作用。  相似文献   

对武术套路训练中负荷强度变化的探讨   总被引：2，自引：0，他引：2  

张选惠  郭永东 《成都体育学院学报》1992,(2)

对武术套路的训练作心率、尿蛋白等生理指标的测试,探讨武术套路训练课的负荷强度,以及不同训练形式,不同训练项目的负荷强度变化,可为武术训练强度的科学安排提供实验依据。  相似文献   

利用大豆内源酶改善腊八豆的品质     

夏岩石  夏延斌  蒋立文 《湖南科技学院学报》2007,28(4):95-99

大豆经内源酶作用生产腊八豆,产品的氨基态氮和还原糖的含量都有增加,货架期内产品的硬度明显降低。试验表明大豆内源酶适宜作用的条件为：大豆经25℃浸后,30℃发芽处理8h,再于40℃处理6h利用内源酶降解大豆本身的部分大分子物质。大豆经此处理后生产的腊八豆与空白处理相比,氨基态氮的含量提高22.5%,产品的硬度降低37.1%。  相似文献   

原发性输尿管肿瘤的诊治     

曾智勇 《襄樊职业技术学院学报》2004,3(5):24-25,28

为探讨原发性输尿管肿瘤的诊断和治疗方法，我们对3例病例临床资料进行回顾并结合文献进行了分析。3例均手术证实，术前2例明确诊断，1例延误诊，均临床治愈。本病早期无明显症状而诊断困难，X线、BUS和CT对诊断价值大。手术方式随病变范围及程度不同而定。  相似文献   

Antidiabetic and ameliorative potential of Ficus bengalensis bark extract in streptozotocin induced diabetic rats     

Mahalingam Gayathri  Krishnan Kannabiran 《Indian journal of clinical biochemistry : IJCB》2008,23(4):394-400

The aim of the present study was to evaluate the antidiabetic and ameliorative potential of aqueous extract of Ficus bengalensis bark in streptozotocin induced diabetic rats. The effect of oral administration of aqueous extract of F. bengalensis bark on blood glucose, serum electrolytes, serum glycolytic enzymes, liver microsomal protein, hepatic cytochrome P-450 dependent monooxygenase enzymes and lipid peroxidation in liver and kidney of streptozotocin -induced diabetic rats was studied. Oral administration of Ficus bengalensis to fed, fasted and glucose loaded diabetic rats significantly [F > 0.05 (ANOVA) and P< 0.05 (DMRT)] decreased the blood glucose level at 5 hrs and restored the levels of serum electrolytes, glycolytic enzymes and hepatic cytochrome P-450 dependent enzyme systems and decreased the formation of liver and kidney lipid peroxides at the end of 12 weeks. Further, the aqueous extract of Ficus bengalensis at a dose of 500mg/kg/day exhibits significant antidiabetic and ameliorative activity as evidenced by histological studies in normal and Ficus bengalensis treated streptozotocin induced diabetic rats. On the basis of our findings, it could be used as an antidiabetic and ameliorative agent for better management of diabetes mellitus.  相似文献