规律性有氧运动对肾炎治疗皮脂刺激效果分析     

司红波 《科技通报》2014,(10)

目的:分析规律性有氧运动对肾炎干预治疗与皮脂刺激调节效果,为肾炎干预治疗提供指导。方法:采用统计调查方法总结分析2013年1月到2013年12月医院所干预治疗的1067例慢性肾炎患者的临床资料,治疗过程,按病因分为:肾源性慢性肾炎、相关性慢性肾炎、高脂血症相关性慢性肾炎、手术相关性慢性肾炎、创伤相关性慢性肾炎和其它因素等6个方面进行分析。以病情感染原因将受试对象划分为6组,每组进行不同程度规律性有氧运动干预治疗,通过对于皮脂刺激调节结果统计分析,测定干预治疗效果。结果:规律性有氧运动对肾源性慢性肾炎患者干预治疗,41%患者肾炎感染程度明显减轻,规律性有氧运动对高脂血症相关性慢性肾炎患者干预治疗,38%患者肾炎感染程度减轻,其他因素引起的肾炎,规律性有氧运动干预治疗无明显效果。结论:规律性有氧运动对肾源性慢性肾炎和高脂血症相关性慢性肾炎的干预治疗起到促进恢复作用。  相似文献   

调节激素刺激对超负荷运动致骨骼坏死的治疗作用     

高红梅 《科技通报》2014,(12)

目的:探讨超负荷运动骨折致骨骼坏死患者的临床特点及调节激素生长刺激治疗方案。方法:分析2013年9月~2014年1月收治31例超负荷运动骨折致骨骼坏死患者的临床资料,总结超负荷运动骨折致骨骼坏死患者的临床特点及调节激素生长刺激治疗方案。结果:31例患者骨骼坏死后早期表现为骨骼受伤部位不适、神经疼痛等,逐渐出现意识变差、神经系统压迫性受损的表现,予早期骨骼固定、骨骼按摩、骨骼触感恢复及骨骼神经恢复等治疗,通过激素生长刺激作用,调节激素对于人体的刺激,使得坏死骨骼生长,31例患者住院1~40 d,11例好转,13例骨骼坏死部分恢复,2例骨骼坏死全部恢复。结论:超负荷运动骨折致骨骼坏死有很强的破坏性,临床表现为骨骼和相关神经衰竭,恢复率低,目前暂无特效调节激素生长刺激治疗方案,及早采取积极的治疗措施:如早期多次骨骼触感恢复或加骨骼神经恢复、大剂量激素的应用对骨骼坏死的救治和改善有重大作用。  相似文献   

SIRTUIN1介导的NIH3T3成纤维细胞昼夜节律时钟基因表达抑制的光生物调节作用   总被引：1，自引：1，他引：0  

吴德峰  刘承宜  朱玲 《体育科学》2011,31(2)

背景和目的:昼夜节律是影响运动成绩的一个重要因素。研究发现,介导运动应激的肿瘤坏死因子(tumor necrosis factor,TNF)能够抑制昼夜节律时钟基因的表达。研究了低强度810nm激光(low intensity 810 nm laserir radiation,LIL)对TNF抑制效应的调节作用。材料和方法:50%马血清休克处理NIH3T3成纤维细胞2h,同步化昼夜节律时钟基因的表达后,加入10ng/mL TNF-alpha抑制它的表达,与此同时给予20min10mW/cm2的LIL照射。36h内,每隔6h检测细胞中时钟基因Clock、Bmal1、Per2、Dbp和烟酰胺腺嘌呤二核苷酸辅酶(nicotinamide adenine dinucleotide,NAD+)依赖的组蛋白去乙酰化酶1(sirtuin1,Sirt1)的mRNA的表达及胞内NAD+和其还原形式NADH的比值NAD+/NADH。结果:TNF-alpha分别在第12h和第18h抑制了Clock(P<0.05)、第18h抑制了Bmall(P<0.05)和Dbp(P<0.005)、第18h和第30h抑制了Per2(P<0.05)及...  相似文献   

Transcriptomic Analysis of Aflatoxin B1-Regulated Genes in Rat Hepatic Epithelial Cells     

杨柳  季静  李光辉  李君文  陈招立  王海勇 《天津大学学报(英文版)》2014,(6):451-457

Aflatoxins are the most popular hepatotoxicants. Chronic exposure to aflatoxins leads to a wide variety of liver diseases, such as hepatocellular carcinoma. In this study, we analyzed the genome wide expression profiles of aflatoxin B1-induced rat hepatic epithelial cells. The expression of 325, 184 and 199 special genes was altered when exposed to 0.03, 0.1 and 0.2 μmol/L aflatoxin B1 respectively, and 239 genes were commonly expressed. After the functional analysis on these dose-special genes, we determined several key pathways related to hepatotoxicity, such as TGF-beta signaling pathway, tight junction, adherens junction, the regulation of actin cytoskeleton, Erb B signaling pathway, p53 signaling pathway, pathways in cancer and axon guidance. Common genes were mainly associated with focal adhesion, ECM-receptor interaction, and cell adhesion molecules. Gene ontology annotations showed a good concordance with these pathways. The quantitative real-time polymerase chain reaction(PCR) analysis of selected genes showed similar patterns in microarrays. The toxicogenomic study provides a better understanding of molecular mechanisms of aflatoxins.  相似文献   

传统聚落景观基因的环境教育特征探析     

胡最  刘沛林  邓运员  郑文武  刘晓燕  邓美容 《衡阳师范学院学报》2014,35(6):137-141

在当今的新形势下,探索传统聚落景观基因资源与构建生态文明战略相结合的环境教育内容体系创新与实施途径具有重要的社会价值。本文结合传统聚落景观基因理论,在深入分析传统聚落景观基因所具有的环境意识特征和所体现的生态环境价值观的基础上,明确了景观基因的环境教育内涵,分析了景观基因对古代环境生态观的传承、认知与体验功能。在前述基础上,本文就实施以景观基因为特色的环境教育的基本途径做了探讨。该文的研究结果表明,将我国传统聚落所体现的生态环境特征纳入到当前的环境教育内容体系当中,是一个值得深入的课题。  相似文献   

用瞬态法调试放大器的频率特性     

倪树范 《绵阳师范学院学报》1994,(Z2)

本文通过分析放大器瞬态特性和频率特性的关系,提出用瞬态测试法对放大器频率特性进行调试的方法。  相似文献   

Human cancer genetics     

Li M  Albertson D 《Journal of Zhejiang University. Science. B》2006,7(2):164-164

Cancer is a genetic disorder.Although heredi-tary cancers account for only a small fraction of all tumors,most cancers are caused by a variable mix of heredity and environment that leads to accumulations of genetic alterations and then uncontrolled cell pro-liferations(Kops et al.,2005).In addition,genetic alteration is one of the a few most important bio-logical factors that determine the diagnosis and prognosis of different cancers and dictate the treat-ment strategies for cancer patients.Fu…  相似文献   

Genes, environment, and dyslexia the 2005 Norman Geschwind memorial lecture     

Olson RK 《Annals of dyslexia》2006,56(2):205-238

This article presents an overview of some methods and results from our continuing studies of genetic and environmental influences on dyslexia, and on individual differences across the normal range that have been conducted over the past 25 years in the Colorado Learning Disabilities Research Center (CLDRC) and in related projects. CLDRC investigators compare the similarities of identical twin pairs who share all their genes and fraternal twins who share half their segregating genes to assess the balance of genetic, shared family environment, and nonshared environment influences on dyslexia and on individual differences across the normal range. We have learned that among the children we have studied in Colorado, group deficits in reading (dyslexia) and individual differences in reading across the normal range are primarily due to genetic influences, and these genetic influences are often shared with some of the same genetic influences on deficits and individual differences in language and ADHD. We have also learned from our molecular-genetic linkage studies that there are regions on several chromosomes likely to contain genes that influence dyslexia. Several specific genes within these regions have been tentatively identified through molecular-genetic association analyses, but much more research is needed to understand the pathways among specific genes, regions of noncoding DNA that regulate the activity of those genes, the brain, and dyslexia. I conclude with a discussion of our research on individual differences in early reading development, on the role of early learning constraints in dyslexia, and on how genetic influences are expressed through their interaction and correlation with the environment.  相似文献   

从侗族款文化看民俗对民间生活的规范力量     

赵黎君 《怀化师专学报》2013,(1):5-7

侗族款文化包括款组织与款词,它是侗族传统民俗文化中最古老最具特色的民俗现象之一。款组织调整规范着整个侗族的民间社会,款词简练精辟地记述了侗族民间社会的各样礼俗。侗族社会每年通过“三月约青”“九月约黄”的款组织活动使整个民间社会学习熟悉款约,以求重返爱与自由的民间生活世界。  相似文献   

关于完善行政规范性文件的思考     

宁清华 《广东技术师范学院学报》2008,(4):74-76

行政规范性文件是我国行政执法实践的重要依据,在实施法律、法规和规章的行政管理中起着非常重要的作用。但其现状不容乐观,我们应采取有效措施,使其更加完善。  相似文献