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To determine the relationship between prescribed training and seasonal-best swimming performance, we surveyed 24 swim coaches and 185 of their age-group and open-class swimmers specializing in sprint (50 and 100 m) and middle-distance (200 and 400 m) events in a summer and winter season. We expressed effects on training as either multiples of swimmers' standard deviations (effect size, ES) or as correlations ( r ). Coaches prescribed higher mileage and longer repetitions of lower intensity to middle-distance swimmers than to sprinters (ES = 0.4-1.5); as competitions approached, repetition intensity and duration of rest intervals increased (ES = 0.5-0.9), whereas session and repetition distances decreased (ES = 0.4-1.3). The 95% likely ranges of the true values for these effects were about - 0.3. Weekly mileage swum at an easy or moderate pace remained at almost 60% of the total throughout both seasons. Interval training reduced gradually from 40% of total distance in the build-up to 30% at the end of tapering. Older swimmers had shorter rests and swam more miles ( r = 0.5-0.8). After partialling out the effects of age on performance ( r = 0.7-0.8), better performance was significantly associated only with greater weekly mileage ( r = 0.5-0.8) and shorter duration of rest intervals ( r = 0.6-0.7) in middle-distance swimmers. Weconclude that periodization of training and differences in training between sprint and middle-distance events were broadly in accord with principles of specificity. Strong effects of specificity on performance were not apparent, but weak effects might have been detected with a larger sample. 相似文献
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档案灾备是近年来档案保护技术在信息化环境下拓展的新领域.本文从档案灾备与业务信息系统灾备对比的角度,分析了档案灾备需求的原理、层级、目标、法律、空间、周期和介质七个方面的特殊性.本文的研究结论对于档案灾备系统的开发具有一定的指导价值. 相似文献
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G. Suman Latha Vijaya Lakshmi H. Surekha Rani K. J. R. Murthy MD FCCP 《Indian journal of clinical biochemistry : IJCB》2005,20(2):170-173
The study was aimed at presence of specific IgE antibody levelsinvitro to the identified antigen. Based on positive skin test with Gynandropsis gynandra and elevated levels of total IgE (>325
IU/ml) 104 patients were selected. Healthy, asymptomatic individuals (25) with low total IgE (<325 IU/ml) were included as
controls. The mean OD values by ELISA for specific IgE were 0.67±0.21, 0.57±0.18 and 0.56±0.18 with whole pollen antigen,
46-37 kD fraction and 36-32 kD fraction, respectively. The specificity and sensitivity between skin test positivity with whole
pollen antigen verses fraction with mol.wt 46-37 kD was 90% and 90% and for fraction with mol.wt 36-32 kD was found to be
81.1% and 89.4%. The clusters with molecular weights 46-37 kD and 36-32 kD may be useful inin vitro diagnostic test. Fractions within these clusters need to be identified for a higher specificity. 相似文献
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Xian‐Jin Xie 《Teaching Statistics》2010,32(3):76-77
Clinically clear, statistically sound and easy‐to‐understand interpretation of a screening result for a serious disease to a patient is very important. 相似文献
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为探讨情绪与自主神经之间的关系,研究选取音乐作为诱导材料,分析活跃类(激昂、快乐、紧张)和镇定类(沉静、悲伤、轻松)情绪刺激对36名大学生指温、心率及呼吸影响的差异性。结果表明:①活跃类均引起三个指标升高;镇定类指温均升高,呼吸与心率均下降。②快乐刺激指温明显低于激昂和紧张的,呼吸明显高于激昂的;轻松刺激呼吸明显快于沉静的。③同种刺激自主生理指标间较少显著相关;但与主观报告较多。 相似文献
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Prakruti Dash 《Indian journal of clinical biochemistry : IJCB》2015,30(2):124-133
Prostate specific antigen is considered to be a tumour marker having maximum utility and specificity for prostate cancer since decades. After the discovery of methods to quantify different molecular fractions of prostate specific antigen (PSA), its usefulness in diagnosing early prostate cancer cases has increased tremendously. The “specificity” of PSA, is now challenged by many studies which proved that PSA, once believed to be secreted exclusively by prostatic epithelium, is also present in females. The exact biological role of extraprostatic PSA is still debatable though many theories substantiated by in vitro evidence has been put forward. With the advent of ultrasensitive analytical techniques, PSA is now quantifiable in female serum in its various molecular forms and this has led to many assumptions of it being useful as a marker in female breast cancers. In a similar scenario to prostate cancer, the ratio of free to total PSA is shown to be useful in detecting early breast cancer cases. It is also shown to be a good prognostic indicator and a predictor of response to therapy and recurrence. Apart from its role in breast cancer, it has been advocated to be a marker of hyper androgenic states in women like hirsutism and polycystic ovarian syndrome. Conflicting reports regarding the role of extra prostatic PSA is accumulating but it has been proven beyond doubt that PSA is no longer specific and confined to prostate gland. Various studies have registered that PSA is an ubiquitous molecule, secreted by hormone responsive organs and its synthesis is stimulated by androgens and progesterone but not oestrogens. In this article, a review of various literatures is done about the presence of extra prostatic PSA, its probable role in those sites as well as its utility as a tumour marker in breast cancer. 相似文献
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通过对持拍隔网对抗类项目竞赛规则的发展阶段、演进主线、对项目所采用的监控手段等在演进过程中所表现的项群化特征及竞赛规则发展的个性化特点的研究提出持拍隔网对抗项类项目竞赛规则的发展具有项群共通性与项目特殊性并存的特点,并对由此引发的持拍隔网对抗类项目竞赛规则间的预见性及竞赛规则的前瞻导向性等继发性问题做进一步探讨。 相似文献
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Walid E. Zahran Magda I. Mahmoud Kamal A. Shalaby Manal H. Abbas 《Indian journal of clinical biochemistry : IJCB》2013,28(3):272-276
Rheumatoid arthritis (RA) is the most common inflammatory systemic autoimmune disease, primarily affecting the peripheral joints. Anti-mutated citrullinated vimentin autoantibodies (anti-MCV) of IgG isotype were shown to be a useful diagnostic marker of RA especially in RA patients who were anti-cyclic citrullinated protein autoantibodies (anti-CCP) negative. Nevertheless, published data correlates rheumatoid factor (RF), anti-CCP or anti-MCV antibodies with either erythrocyte sedimentation rate (ESR) or serum C-reactive protein (CRP) as markers of disease activity, not investigated the possible correlations of RA autoantibodies towards ESR and CRP in comparison. Herein, we aim to evaluate the usefulness of anti-MCV as a dependable marker in established RA compared with anti-CCP and RF antibodies and to examine correlations between RF, anti-CCP and anti-MCV antibodies towards ESR and serum CRP. Serum RF-IgA, RF-IgM, anti-CCP and anti-MCV levels were measured in 30 patients with RA and 40 patients with other autoimmune diseases (non-RA) compared with 20 normal subjects. Specificity, sensitivity and AUC for RF antibodies, anti-CCP and anti-MCV were calculated towards RA diagnosis. Our results showed that ESR and CRP had significantly higher values in both RA and non-RA patients compared with our healthy controls with observed significant increment in RA patients compared with non-RA patients. An important finding from our study is that 33.3 % of RA patients were anti-CCP negative but being positive towards anti-MCV. Also, in-between 36.7 up to 40 % of RA patients were RF-IgA and RF-IgM negative while being anti-MCV positive. Anti-MCV antibodies showed the highest specificity and sensitivity (97.5 and 86.6 %, respectively) towards RA diagnosis with the highest AUC value (0.920) compared with anti-CCP and RF antibodies. Correlation analyses revealed that there was no significant correlation between ESR along with CRP towards RF-IgA, RF-IgM and anti-CCP while profound highly significant correlation exhibited between ESR and CRP towards anti-MCV data (r = 0.879 and 0.994, respectively). Thus, our data suggest that the assessment of serum anti-MCV autoantibodies along with ESR and CRP considered as a simple laboratory regime for monitoring RA patients to assess and follow-up disease activity. The addition of anti-MCV autoantibodies to serologic markers in the ACR/EULAR classification criteria for RA will add points for patients with negative anti-CCP and RF antibodies. 相似文献