Long-term endurance training increases serum cathepsin S and decreases IL-6 and hsCRP levels     

Michael Sponder  Ioana-Alexandra Campean  Michael Emich  Monika Fritzer-Szekeres  Brigitte Litschauer  Jutta Bergler-Klein 《Journal of sports sciences》2017,35(21):2129-2134

Cathepsin S (CS) was shown to play a key role in cancer progression, atherosclerosis, heart valve disease, insulin resistance and diabetes mellitus. The present prospective study aimed to investigate the influence of sports on CS, interleukin-6 (Il-6) and high-sensitivity C-reactive protein (hsCRP) levels.

Ninety-eight of 109 participants completed the study. Ergometries were performed at baseline and after 8 months to evaluate/quantify the performance gain. Blood samples were taken at baseline and every 2 months. CS was measured by ELISA (enzyme-linked immunosorbent assay). Compared to the control group (mean performance gain ?3.41 ± 4.62%) we observed a significant physical-activity-induced increase of CS levels (3.45–3.73 ng · ml^?1; P = 0.027) and a significant decrease of Il-6 (2.43–1.91 pg · ml^?1; P = 0.031) and hsCRP-levels (0.11–0.09 mg · dl^?1; P = 0.001) in the intervention group (mean performance gain: 12.13 ± 6.32%). Furthermore, the tendency of the progression was significant for CS and Il-6 (P = 0.002/0.033).

We could show a significant sports-induced decrease of the classic inflammation parameters hsCRP/Il-6, probably expressing a downregulation of permanently prevalent inflammation processes. Simultaneously CS levels increased significantly. Our results show that increasing CS amounts are not simply to equal with an enhanced inflammation status and might even have beneficial effects on inflammation and angiogenesis.  相似文献   

高校实验动物管理系统的设计     

张志平 《黑龙江科技信息》2010,(20):155-155

介绍了利用ASP.NET技术开发的B/S模式的高校实验动物管理系统,重点阐述了系统的构建、应用与特点及其实现的一些关键技术。  相似文献   

Solomon,Lord of the Rings: Fashioning the Signet of Power from Electrum to Nuḥās*     

Allegra Iafrate 《Al-Masaq: Islam & the Medieval Mediterranean》2016,28(3):221-241

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Exploring Verbal,Visual and Schematic Learners' Static and Dynamic Mental Images of Scientific Species and Processes in Relation to Their Spatial Ability     

Sulaiman M. Al-Balushi 《International Journal of Science Education》2013,35(3):460-489

The current study compared different learners’ static and dynamic mental images of unseen scientific species and processes in relation to their spatial ability. Learners were classified into verbal, visual and schematic. Dynamic images were classified into: appearing/disappearing, linear-movement, and rotation. Two types of scientific entities and their related processes were investigated: astronomical and microscopic. The sample included 79 female students from Grades 9 and 10. For the purpose of the study, three instruments were used. The Mental Images by Guided Imagery instrument was designed to investigate participants' visualization of static and dynamic mental images. The Water-Level Task was adopted to estimate participants' spatial ability. The Learning Styles Inventory was used to classify participants into verbal, visual and schematic learners. The research findings suggest that schematic learners outperformed verbal and visual learners in their spatial ability. They also outperformed them in their vividness of microscopic images; both micro-static and micro-dynamic images; especially in the case of appearing/disappearing images. The differences were not significant in the case of astronomical images. The results also indicate that appearing/disappearing images received the least vividness scores for all three types of learners.  相似文献   

An intervention in the Halliwick Method procedures (swimming) for a group of individuals with Downs syndrome     

D. Kokaridas  N. Aggelopoulou-Sakadami  B. Walters 《欧洲特需教育杂志》2013,28(2):218-231

The purpose of this study was to intervene in the process of the Halliwick Method (swimming), in order to improve the method, or some of its aspects, for a sample of 14 individuals with Downs syndrome (aged six to 21 years), using both an individualized educational setting approach and a differentiation of the elements of the Halliwick Method. The pre-intervention phase included medical examination, IQ, measurement of the behaviour according to the Rutter Scale and a Test of Physical Performance for each subject. Next, the subjects were assigned to seven pairs of case studies, where each individual following a Halliwick Methods swimming programme was paired with an individual following a modified swimming programme based on the same method, on physical health variables, IQ, behaviour and motor abilities. The duration of each swimming programme was 24 weeks for each individual, at a frequency of once per week, for 40 minutes. In the light of the findings of this study, further recommendations for the improvement of Halliwick Method procedures were made, common factors that affected the performance of each individual were identified and their relation with performance was explored.  相似文献   

基于Winsock的局域网监控系统研究     

刘立峻  滕蔚 《人天科学研究》2010,(9):153-154

介绍了利用Visual C＋＋的网络组件及TCP/IP协议等技术的局域网监控系统,该系统由客户端和服务器端两部分组成,可实现对网络的运行状态进行实时监控,获取计算机运行状态信息等功能。  相似文献   

基于Matlab/Simulink的电工学电路仿真     

朱霞清 《黑龙江科技信息》2010,(1):86-86,53

电工学是工科类专业的技术基础课程,实践性和应用性都很强,其教学效果的好坏直接影响着后续专业课的学习。在电工学教学实践中,引入MATLAB仿真工具,将传统授课方式和计算机技术有机地结合起来。教学实践表明该法不仅能提高教学质量,而且能提高学生综合素质。  相似文献   

Perceived and experienced stigma among people living with HIV: Examining the role of prior stigmatization on reasons for and against future disclosures     

Danielle Catona  Kathryn Greene  Kate Magsamen-Conrad  Amanda Carpenter 《Journal of Applied Communication Research》2016,44(2):136-155

HIV remains a significant health concern entering the fourth decade of the epidemic [Centers for Disease Control and Prevention. 2014. HIV basics. Retrieved from http://www.cdc.gov/hiv/basics/index.html], and people living with HIV continue to grapple with stigma. This study uses Leary and Schreindorfer's [1998 Leary, M. R., &; Schreindorfer, L. S. (1998). The stigmatization of HIV and AIDS: Rubbing salt in the wound. In V. J. Derlega &; A. P. Barbee (Eds.), HIV and social interaction (pp. 12–29). Thousand Oaks, CA: Sage. [Google Scholar]. The stigmatization of HIV and AIDS: Rubbing salt in the wound. In V. J. Derlega &; A. P. Barbee (Eds.), HIV and social interaction (pp. 12 Lekas, H. M., Siegel, K., &; Schrimshaw, E. W. (2006). Continuities and discontinuities in the experiences of felt and enacted stigma among women with HIV/AIDS. Qualitative Health Research, 16, 1165–1190. doi:10.1177/1049732306292284[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]–29 Lekas, H. M., Siegel, K., &; Schrimshaw, E. W. (2006). Continuities and discontinuities in the experiences of felt and enacted stigma among women with HIV/AIDS. Qualitative Health Research, 16, 1165–1190. doi:10.1177/1049732306292284[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]). Thousand Oaks, CA: Sage] conceptualization of stigma to explore prior stigmatization on reasons for and against future disclosures. We interviewed HIV+ individuals (N?=?59) and used a combination of deductive and inductive coding to analyze participants’ responses. Deductive codes consisted of four stigma characteristics (pose a threat to others’ health and safety, deviate from group standards, create negative emotional reactions in others, and failure to contribute), experiences of feeling stigmatized due to HIV status (yes or no), and the degree to which HIV stigma was a concern (major, minor, or no concern). Inductive coding identified examples of perceived and experienced stigma and stigma concerns on future disclosure decision-making. Practical implications discuss individual, institutional, and societal stigma-reduction interventions and programs.  相似文献   

三层C/S结构报刊发行信息系统的设计实现     

杜冬梅  盖建荣  吴梅娟 《石家庄职业技术学院学报》2007,19(6):37-40

阐述了三层C/S体系结构的优点,Tuxedo中间件的主要功能和特点.介绍了在Linux操作系统下基于Tuxedo的三层C/S体系结构的报刊发行信息系统的设计与实现.  相似文献   

The effect of modifiers on the stability of a vinyl acetate/ethylene copolymer dispersion     

Jane L. Down 《文物保护研究》2016,61(1):26-45

This paper examines the effect of modifiers on the stability of a vinyl acetate/ethylene copolymer dispersion adhesive upon aging. Eighteen common modifiers were added to a well-characterized vinyl acetate/ethylene copolymer dispersion (Dur-O-Set^® E-150) in known concentrations and dry-film samples were subjected to 16–17 years of dark aging and seven to eight years of light aging. Yellowing, pH, gloss, swelling, cohesive strength, and flexibility were monitored for changes upon aging. Generally, the neat Dur-O-Set^® E-150 (no additives) was found to become acidic on aging, but was fairly resistant to yellowing. It also swelled substantially in toluene, was of high gloss, medium strength, and flexible, and remained so on aging. No modifier was found to improve these properties. Various solvents, wetting agents, and thickeners did not alter the properties by much, while plasticizers, freeze-thaw stabilizer, glycerin, and certain fillers had a more negative effect.  相似文献