The Seljuk Sultanate of Rūm and the Turkmen of the Byzantine frontier, 1206–1279*     

A.C.S. Peacock 《Al-Masaq: Islam & the Medieval Mediterranean》2014,26(3):267-287

This article examines the frontier between the Seljuk Sultanate of Rūm and its Byzantine neighbours in the thirteenth century, concentrating on the place of these frontier districts within the Seljuk state. Scholarship on the frontier, influenced by the ideas of Paul Wittek, has seen it as something of a “no man's land”, politically, economically, culturally and religiously distinct from the urban heartland of the Seljuk sultanate in central Anatolia, dominated by the nomadic Turks, the Turkmen, who operated largely beyond sultanic control. It is often thought that the Seljuk and Greek sides of the border shared more in common with each other than they did with the states of which they formed a part. In contrast, this article argues that in fact the western frontier regions were closely integrated into the Seljuk sultanate. Furthermore, with the Mongol domination of the Seljuk sultanate in the second half of the thirteenth century, the Seljuk and Mongol elites became increasingly involved in this frontier region, where some of the leading figures of the sultanate had estates and endowments.  相似文献   

间歇运动激活心梗大鼠心肌NRG1-PI3K/Akt通路抑制心肌细胞凋亡     

谭支内  蔡梦昕  陈婷  Shaojun Du  田振军 《北京体育大学学报》2016,39(6):69-76+83

摘要：目的: 探讨心脏NRG1在间歇运动激活心梗(myocardial infarction，MI)大鼠心肌NRG1-PI3K/Akt通路抑制心肌细胞凋亡的作用。方法：雄性SD大鼠48只，随机分为假手术组(S)，心梗安静组(MI)，心梗+间歇运动组(ME)，心梗+间歇运动+抑制剂组(MEA)，每组12只。采用左冠脉前降支结扎法建立MI模型。S组手术仅穿线不结扎。ME组和MEA组在MI术后1wk进行跑台间歇运动。运动开始速度为10m/min运动10min后，速度逐渐增至25m/min×7 min，再以15 m/min×3min运动，之后依次交替进行。60min×1次/d，5d/1wk×8wk。训练结束后次日，腹腔麻醉，颈动脉插管测定LVSP、LVEDP及±dp/dtmax。之后开胸摘取心脏，进行组织学制片，Masson染色。荧光实时定量PCR测定心肌NRG1及其受体ErbB2/4表达。Western Blot法检测心肌NRG1、ErbB2/4、PI3K/Akt、Bcl-2和Bax蛋白含量。Caspase3表达及TUNEL检测观察分析心肌细胞凋亡情况。结果: MI组胶原容积百分比(CVF)和LVEDP较S组显著升高(P<0.01,P<0.01)，LVSP和±dp/dtmax显著降低(P<0.01,P<0.01)。且MI后心肌ErbB4 mRNA表达显著降低(P<0.01)，心肌NRG1、ErbB2和ErbB4蛋白表达显著降低(P<0.05,P<0.01,P<0.01)，PI3K/Akt蛋白表达及Bcl-2/Bax比值显著降低(P<0.01,P<0.01)，TUNEL阳性细胞数和Caspase3活力显著增加(P<0.01,P<0.01)。ME组CVF和LVEDP较MI组显著降低(P<0.01,P<0.01)，LVSP和±dp/dtmax显著升高(P<0.01,P<0.01)，心肌NRG1、ErbB2和ErbB4 mRNA及蛋白表达均显著增加(P<0.01,P<0.01,P<0.01)，PI3K/Akt蛋白表达和Bcl-2/Bax比值显著增加(P<0.01,P<0.01)，TUNEL阳性细胞数和Caspase3活力显著降低(P<0.01,P<0.01)，且运动效应被抑制剂AG1478显著减弱。结论:间歇运动可通过激活心肌NRG1及其受体表达，上调PI3K/Akt蛋白表达，抑制心肌细胞凋亡和胶原过度增生，改善心功能。  相似文献   

Online visibility of software-related web sites: The case of biomedical text mining tools     

Gael Pérez-Rodríguez  Martín Pérez-Pérez  Florentino Fdez-Riverola  Anália Lourenço 《Information processing & management》2019,56(3):565-583

  相似文献   

一种机载重轨InSAR高精度三维定位方法     

董小桐  韩春明  岳昔娟  赵迎辉 《中国科学院大学学报》2019,36(6):844-850

在重轨干涉实际测量中，两次飞行航迹难以保持高度重合，飞行高度和姿态不稳定，干涉图像对存在明显不规则的相对形变，难以进行三维定位。通过分析重轨机载InSAR图像对的几何形变和形成原因，提出一种从精准的InSAR成像几何关系出发，通过修正成像参数，实现机载重轨InSAR高精度三维定位的方法。该方法通过引入地面控制点，实现干涉图像对精准的相对定位，生成高精度DEM；并利用高精度DEM，实现机载重轨InSAR高精度三维定位。对比检查点实测结果和定位结果，表明该方法可有效地解决机载重轨InSAR的三维定位困难的问题。  相似文献   

Where are we now? A review of research on the history of women's soccer in Ireland     

Helena Byrne 《Sport in History》2019,39(2):166-186

ABSTRACT

It is a common fact that women's sport and leisure history, especially in male dominated spheres, and more specifically football, have been ignored by many academics. However, in recent years there have been major developments in digital technology that have changed the nature of the type of research that can be done. Access to tools to facilitate field research are relatively cheap and with the high volume of digitisation projects that have taken place over the last few years as well as the increasing number of born digital resources that have been published, there are new opportunities. In relation to women's soccer in Ireland, this paper asks the question – where are we now? The argument will review the current literature on this subject and outline potential approaches for future research.  相似文献   

Scapular motion adaptations in junior overhead athletes: a three-dimensional kinematic analysis in tennis players and non-overhead athletes     

Elif Turgut  Filiz Fatma Colakoglu  Gul Baltaci 《Sports biomechanics / International Society of Biomechanics in Sports》2019,18(3):308-316

Adult overhead athletes without a history of shoulder injury show scapular adaptations. There is a lack of detailed assessment of scapular kinematics in junior overhead athletes. This study aims to investigate three-dimensional scapular kinematics in junior overhead athletes. We recruited a total of 20 junior tennis players and 20 healthy children without participation in any overhead sports in this study. Bilateral scapular kinematic data were recorded using an electromagnetic tracking device for scapular plane glenohumeral elevation. The data were further analysed at 30°, 45°, 60°, 90° and 120° during glenohumeral elevation and lowering. Statistical comparisons of the data between groups (junior overhead athletes and non-overhead athletes) and sides (serve dominant and non-dominant shoulders of the overhead athletes) were analysed with the ANOVA. Comparisons showed that, in general, the scapula was more upwardly rotated and anteriorly tilted in overhead athletes when compared to non-overhead athletes, however there was no side-to-side differences when serve dominant and non-dominant shoulders compared in junior overhead athletes. The serve dominant arm of junior overhead athletes had alternations in scapular kinematics when compared with the non-overhead athletes. These findings provide clinical evaluation implications and the need for clinicians to assess for potential adaptations in junior overhead athletes.  相似文献   

展开式变奏在勃拉姆斯《D大调小提琴协奏曲》中的创作技法研究     

偶潇潇 《安徽职业技术学院学报》2020,(1):58-62

文章通过对勃拉姆斯《D大调小提琴协奏曲》的详细剖析,从主题构建、呈示部创作、全曲整合多角度分析阐述展开式变奏在特定作品中的实际运用,并探析在这首作品中展开式变奏所呈现的独特创作技法,为研究勃拉姆斯创作手法中的创新性提供一定的参考。  相似文献   

美国妇女选举权档案开发利用的特色分析及启示     

黄霄羽  位焕锦  黄敏 《北京档案》2020,(5):40-43

美国国家档案馆为纪念宪法《第十九条修正案》100周年,发起一项为期18个月的全国性倡议,带动各州庆祝妇女选举权。本文分析指出美国妇女选举权档案开发利用的内容特色——主题集中、关注个体和突出人物;方式特色——多媒介、数字化和关联式开发并行,最后总结出对我国的启示——档案开发利用宜主题集中、方式多样、把握时机的持续性。  相似文献   

根据实洋/总成本曲线对图书印数进行优化控制     

黄新路  张晶 《出版科学》2008,16(1):29-33

本文整理出版及印刷工作实践中的数据,生成收支-印量关系曲线,通过对曲线的分析,推导出收支平衡点印数精确值的计算公式,用以探讨图书出版过程中主要因素对成本的影响,目的在于对图书印数进行优化控制。  相似文献   

基于运动捕获数据的三维角色动画设计     

叶福军  潘瑞芳 《新闻界》2008,(6):170-172

本文研究了怎样把现有的人体运动数据重新定向到新的动画角色对象上,并实现了一个原型系统——盼盼三维角色动画系统。通过这种方法,用户只需要从动画库中选择所需的人体运动,便可方便地控制任意三维动画角色的运动和变形,从而重用现存的人体运动数据去控制新的角色,创作出一些夸张的动画效果。  相似文献