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Kevin R. Parker Sankara Subramanian Srinivasan Robert F. Houghton Nima Kordzadeh Karoly Bozan Thomas Ottaway Bill Davey 《Education and Information Technologies》2017,22(4):1497-1513
Curriculum development is particularly challenging in computing-related disciplines as the computing industry changes more quickly than most. As information technology degrees have become relatively pervasive, some institutions that offer information systems degrees have recognized a need to develop specialist studies in information systems. This detailed case study shows the forces related to a successful implementation of new Health Informatics degrees. The case describes both an unsuccessful and then a successful attempt at essentially the same curriculum development. Although the case includes some local political factors, these represent typical considerations that a curriculum developer is likely to encounter. 相似文献
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Ajay Kumar T. A. Venkita Subramanian Usha P. Sharma 《Indian journal of clinical biochemistry : IJCB》1992,7(2):165-168
Protein fraction termed P2 was obtained from sonicates of Mycobacterium smegmatis, subjected to ammonium sulphate precipitation. P2 fraction was further fractionated into 4 fractions (PeakI-IV) by DEAE cellulose ion-exchange chromatography. ELISA was performed
on the sera of 104 tuberculous cases and 62 controls, using P2 fractions Peak I as test antigens. Though the mean ELISA values in tuberculous cases were higher than the controls, no statistically
significant difference was found between the two. Antigens P2, Peak I and IV were tested on Western blots with pooled sera from tuberculous cases as well as controls. P2 fraction, Peak-I and IV were separated on PAGE-SDS, electroblotted onto nitrocellulose Sheets and the blots were subjected
to ELISA. Peak IV appeared as a single band (M.W. 55,000). P2 fraction exhibited some discriminatory bands on development of blots. 相似文献
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In this part we shall outline the challenges one faces while developing time-domain radiofrequency (RF) EPR imaging spectrometer for in vivo studies. Time-domain or FT-EPR is quite a different animal compared to the CW modality. The evolution of FT-EPR instrumentation at the National Cancer Institute, NIH, USA and representative examples of application in cancer research are outlined in this article. 相似文献
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EPR (Electron Paramagnetic Resonance) imaging is particularly useful in monitoring hypoxic zones in tumors which are highly resistant to radiation and chemotherapeutic treatment. This first part of the article covers aspects of CW (continuous wave) imaging with details of FT (pulsed Fourier Transform)-EPR imaging covered in Part 2, to be published in the next issue of Resonance. 相似文献
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Strategic alliances are important channels for interfirm learning, especially for small firms that are resource constrained. Of the several alliance attributes, technological distance between partners (measured as the distance between partners’ innovative outcomes) is shown to have a significant influence on the learning benefits from strategic alliances. Drawing upon the theory of recombination, our study argues that the influence of technological distance on learning is best understood by not only measuring the distance between innovative outcomes, but by also taking into consideration the knowledge elements underlying the innovative outcomes. We develop a concept of knowledge base homogeneity that captures the extent to which the innovative outcomes of partnering firms draw upon similar sets of knowledge elements. Using patent and alliance data from 201 small biotechnology firms during the period 1996–2010, we confirm that the technological distance has an inverted u-shaped relationship on interfirm learning. We further demonstrate that this u-shaped relationship is moderated by the knowledge base homogeneity between partners, such that benefits of technological distance are enhanced and the costs of technological distance are mitigated when the knowledge base homogeneity between alliance partners is high. The results have important implications for interfirm learning, especially in the context of small firms that are limited in their knowledge stocks. 相似文献