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A. K. Pradhan A. K. Shukla M. V. R. Reddy N. Garg 《Indian journal of clinical biochemistry : IJCB》2004,19(1):83-87
Oxidative stress was assesed by estimating lipid peroxidation product (LPO) in the form of thiobarbituric acid reactive substances
(TBARS), enzymatic antioxidants in the form of superoxide dismutase (SOD), catalase and nonenzymatic antioxidant vitamins
e.g. vitamin C, β carotene and vitamin E in either serum or plasma or erythrocytes in 190 cases of age related cataract in
the age group of 50–80 years. 190 cases were grouped into three morphological types namely, 73 cases of cortical, 77 cases
of posterior subcapsular and 40 cases of nuclear cataract and values of LPO and antioxidants were compared with 78 cases of
age matched healthy control groups. Plasma TBARS levels were cataract cases when compared with control groups. There were
no significant differences in the erythrocyte levels of catalase and plasma levels of Vit E between cataract cases and control
groups. No significant changes of parameters were seen among three different morphological types of age related cataract.
The present study shows that the oxidative stress may play an important role in the age related cataract. 相似文献
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Ti-6A1-4V super alloy is an important engi- neering material with good strength to weight ratio and a wide range of applications in a number of engineering fields because of its excellent physical and mechanical properties. This work determines optimum process parameters such as pulse on time, peak current, gap voltage and flushing pressure, which influence the micro-electro discharge machining （EDM） process during machining of Ti-6AI-4V using combined methods of response surface methodology （RSM） and fuzzy-technique for order pref- erence by similarity to ideal solution （TOPSIS）. Central composite design （CCD） is used in the experimental investigation. A decision making model is developed to identify the optimum process parameters in the micro- EDM process, which influences several machining criteri- ons such as material removal rate （MRR）, tool wear rate （TWR）, overcut （OC） and taper. Triangular fuzzy numbers are used to determine the weighting factor for each process criterion. Further a fuzzy-TOPSIS method is used to select the most desirable factor level combinations. The proposed technique can be used to select optimal process parameters from various sets of combinations of process parameters in a micro-EDM process. 相似文献
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Uma Pradhan Shivana Shrestha Karen Valentin 《Globalisation, Societies & Education》2019,17(5):561-573
ABSTRACTCommunity-based school governance has been promoted as a popular policy for decentralisation of education around the world. Within this policy, schools are expected to create institutional spaces such as School Management Committees with an assumption of reciprocal relation between school and community. This article questions the simplistic assumption through an ethnographic study of community-school relationship in Nepal. While these relationships may conflict with the kind of reciprocity assumed in school governance policies, we argue that this disjunctured reciprocity, firstly, reflects the gap between policy blueprints and action, and, secondly, reveals the competing logics of community-school relations which remain unacknowledged. 相似文献
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基于MODIS的西藏高原土地覆盖分类研究 总被引：1，自引：0，他引：1
嵌的MODIS遥感图像,用最大似然估计分类器对西藏高原的土地覆盖类型进行了分类,并采用西藏高原数字高程模型(DEM)对MODIS分类结果进行了分析和改进,最后分别用混淆矩阵和图集中西藏高原植被分类汇总面积对MODIS土地覆盖分类结果进行了分类精度评价。结果表明:①MODIS遥感图像能够有效地分类出西藏高原的主要土地覆盖类型;②根据西藏高原植被的垂直带性分布特点,由DEM改进的MODIS土地覆盖分类精度明显提高,主要土地覆盖类型的面积绝对误差都小于2%,其中,河流与湖泊、森林、高寒荒漠、作物和山地草原的绝对误差都在1%以下;③混淆矩阵分析的平均分类精度为87.68%。 相似文献
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Uma Pradhan 《Ethnography and Education》2017,12(3):381-394
Scholars in education have drawn our attention to the ways in which social power and control manifests in the process of knowledge production in education institutions especially through school curriculum. In this paper, I analyse school textbooks along with classroom instruction events and everyday practices in a mother-tongue school in Nepal. Drawing on the concept of ‘legitimate knowledge’, this paper discusses mother-tongue education as a struggle over symbolic resources, whereby familiarity with ‘daily life in the locality’ is discursively drawn upon to articulate mother tongue as an effective pedagogy and legitimate knowledge. The paper argues that the introduction of mother tongue in the school curriculum is, therefore, more than an addition of new language. It is a process of negotiating what it means to ‘know’ things in school. In doing so, this paper illustrates a dynamic process of re-signification of local languages, knowledge and identities that is underway. 相似文献
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Moushumi Lodh Debkanta Pradhan Abhishek Mukherjee 《Indian journal of clinical biochemistry : IJCB》2011,26(4):423-425
We report an unusual presentation of primary biliary cirrhosis. We present the case of a 31-year-old Indian woman who presented
to the hospital with non specific complaints of gastritis, reduced appetite and marked weight loss and no complaints of pruritus.
Serum liver enzymes were elevated. Cytoplasmic pattern of antinuclear antibodies was found on immunofluorescence microscopy
accompanied by positive anti smooth muscle antibody. Endoscopy revealed esophageal varices. Following a liver biopsy, the
diagnosis of primary biliary cirrhosis was made. It is important to consider the diagnosis of hepatic cirrhosis when patient
presents with gastritis, reduced appetite and marked weight loss in both the presence and absence of ascites. 相似文献
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Mark J. Jordans Annalise S. Keen Hima Pradhan Wietse A. Tol 《International journal for the advancement of counseling》2007,29(1):57-68
The aims of this qualitative study were (1) to add to the understanding of the growing field of psychosocial counselling in
Nepal, and (2) gather concrete points for improvement of services. Semi-structured interviews were conducted with clients
(n = 34), para-professional counsellors (n = 26) and managers (n = 23) of organizations in which psychosocial counselling was taking place. The main findings were that stakeholders generally
presented a positive view of the significance and supportive function of psychosocial counselling, while providing useful
suggestions for improvement. Matters of ongoing training and supervision, confidentiality and integration of counselling within
mainstream care provision need to be addressed and potentially adapted. Implications for other non-Western countries with
little mental health resources are discussed. 相似文献
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Suchitra Kumari Tarun Kumar Panda Tapaswini Pradhan 《Indian journal of clinical biochemistry : IJCB》2017,32(2):134-141
The mechanical properties of extracellular matrix (ECM) and connective tissues is largely dependent on the collagen and elastin structure. Lysyl oxidase (LOX) plays a critical role in the formation and repair of the ECM by oxidizing lysine residues in elastin and collagen, thereby initiating the formation of covalent cross linkages which stabilize these fibrous proteins. Due to its multiple functions both extracellularly and intracellularly, lysyl oxidase is involved in several processes in the tumorigenic pathway, in many different cancer types and stages. Alteration in LOX activity is implicated in many diseases and disorders including inflammation and inflammatory diseases, fibrosis of distinct organs and fibrotic disorders, cancer promotion and progression. There are only sparse reports of mutations or epigenetic alterations in the LOX gene. This review provides the recent clinical developments in the molecular mechanisms and pathologic process, pointing out LOX as a potential therapeutic target in translational medicine. 相似文献
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