Professionalisation as development and as regulation: Adult education in Germany,the United Kingdom and India     

Lesley Doyle  Regina Egetenmeyer  Chetan Singai  Uma Devi 《International Review of Education/Internationale Zeitschrift für Erziehungswissenschaft/Revue internationale l'éducation》2016,62(3):317-341

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Genetics of Obesity     

Apurva Srivastava  Neena Srivastava  Balraj Mittal 《Indian journal of clinical biochemistry : IJCB》2016,31(4):361-371

Numerous classical genetic studies have proved that genes are contributory factors for obesity. Genes are directly responsible for obesity associated disorders such as Bardet–Biedl and Prader–Willi syndromes. However, both genes as well as environment are associated with obesity in the general population. Genetic epidemiological approaches, particularly genome-wide association studies, have unraveled many genes which play important roles in human obesity. Elucidation of their biological functions can be very useful for understanding pathobiology of obesity. In the near future, further exploration of obesity genetics may help to develop useful diagnostic and predictive tests for obesity treatment.  相似文献   

Effect of arogh—A polyherbal formulation on the marker enzymes in isoproterenol induced myocardial injury     

S. Suchalatha  C. S. Shyamala Devi 《Indian journal of clinical biochemistry : IJCB》2004,19(2):184-189

To study the protective role of Arogh on isoproterenol induced myocardial damage in rats. The effect of Arogh pretreatment on isoproterenol induced myocardial damage was assessed by studying the levels of lipid peroxides and changes in the activity of marker enzymes such as creatine kinase, lactate dehydrogenase and transaminases in serum and heart tissue. In isoproterenol administered rats, a significant decrease was observed in the activity of marker enzymes in the heart with a corresponding increase in their levels in serum. Lipid peroxide levels increased significantly in the serum and heart. In rats pretreated with arogh, the level of lipid peroxides and the activity of marker enzymes were maintained at near normal values. Pretreatment with Arogh offered a protective effect against isoproterenol induced myocardial damage in rats as evidenced by LDH isoenzyme patterm and histopathological studies of heart tissue.  相似文献   

Evaluation of urinary abnormalities in urolithiasis patients: A study from North India     

R. Kumar  R. Kapoor  B. Mittal  A. Kumar  R. D. Mittal 《Indian journal of clinical biochemistry : IJCB》2003,18(2):209-215

Metabolic abnormalities were investigated in 44 stone patients with first time (group 1) and 56 with 2 times stone formation (group 2), and in 25 normal individuals. 24hr urine was analysed spectrophotometrically for oxalate, calcium, magnesium, citrate, uric acid, phosphate and creatinine. Hypocitraturia and hyperoxaluria were the common abnormalities in the stone formers. Stone patients had significantly higher urinary oxalate, calcium and uric acid and lower phosphate than normal individuals. Citrate/calcium and magnesium/calcium ratio were significantly high in normal individuals than stone formers. Patients in group 2 excreted significantly higher urinary calcium and lower citrate that patients in group 1. Citrate/calcium ratio was higher in group 1 than group 2. Hypocitraturia, hyperoxaluria, hypercalciuria and increased citrate/calcium and magnesium/calcium ratio seem to be an essential risk factor for stone formation. Patients with recurrent stone formation could be distinguished from patients with first time stone formation on the basis of urinary calcium and citrate.  相似文献   

Lipid peroxidation and antioxidant vitamins in urolithasis     

J Kato  Alice Abraham Ruram  S Sekharjit Singh  S Bilasini Devi  Th Ibetombi Devi  W Gyaneshwar Singh 《Indian journal of clinical biochemistry : IJCB》2007,22(1):128-130

The present, study was conducted to determine the level of malondialdehyde (MDA) as an index of free radial induced lipid peroxidation and antioxidant vitamins-vitamins A, vitamin C and vitamin E in 75 confirmed cases of urolithiasis. Significantly high level of MDA (p<0.001) with significantly low levels of vitamin E (p<0.001) and vitamin A (p<0.001) with no significant decrease in vitamin C (p>0.05) were observed in the plasma of urolithiasis cases as compared to normal controls. In conclusion, it appears that a role of lipid peroxidation and oxidative function exists in the pathogenesis of urolithiasis. But, the exact mechanism how this occurs remains to be elucidated.  相似文献   

A new venture     

P. Rama Rao 《Resonance》1996,1(1):1-1

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Silica from ash     

Davinder Mittal 《Resonance》1997,2(7):64-66

A simple chemical process is described for extracting amorphous silica from rice husk.  相似文献   

Fractals and the large-scale structure in the Universe     

A. K. Mittal  T. R. Seshadri 《Resonance》2002,7(4):39-47

In Part 1 of this article, we had introduced the reader to some basic concepts of fractals and some operational algorithms to characterize them. We had also pointed out and clarified some common misconceptions about fractals. In this part we apply the fractal concepts to large-scale structures in the Universe. In particular we discuss the claim by some investigators that the distribution of galaxies in the Universe is a fractal. This is contrary to the standard view that the Universe is homogeneous and isotropic on large scales. Also discussed is the controversy as to whether the matter distribution in the Universe is a fractal on large-scales.  相似文献   

Fractals and the large-scale structure in the Universe     

A K Mittal  T R Seshadri 《Resonance》2002,7(2):6-19

During the last decade it has been argued by some investigators that the distribution of galaxies in the Universe is a fractal. This is contrary to the standard view that the Universe is homogeneous and isotropic on large scales. In this article, the basic concepts of fractals and their characterization are introduced with the help of simple examples. The applications of these concepts in the context of cosmology will be discussed in the second part. A K Mittal is currently a visiting scientist at Harish-Chandra Research Institute, Allahabad, on leave from the University of Allahabad. His research interests include chaos, fractals and their applications, partleularly in cosmology and in weather prodiction. T H Seshadri is at the Department of Physics and Astrophysics, University of Delhi. He is presently on lien from Harish-Chandra Research Institute, Allahabad. Areas of his interest include cosmic microwave background radiation, large scale structures in the Universe and application of fractals in these.  相似文献   

    

Thyagaraju K.  Hemavathi B.  Vasundhara K.  Rao A. D.  Devi K. N. 《Journal of Zhejiang University. Science. B》2005,6(8):759-769

A comparative study was made on the tissue specific expression of glutathione transferases (GST) in brain and testis after exposure of rat to phenobarbitol (PB) and β-methylcholanthrene (MC). Glutathione transferases, a family of multifunctional proteins are involved in intracellular transport processes and in detoxication of electrophilic xenobiotics by catalyzing reactions such as conjugation, isomerization, reduction and thiolysis. On purification, the yield of GST proteins by affinity chromatography was 39% in testis and 32% in brain. The affinity purified testis GSTs were resolved by chromatofocusing into six anionic and four cationic isozymes, and in brain glutathione transferases were resolved into four anionic and three cationic isozymes, suggesting the presence of multiple isozymes with Yc, Yb, Yβ and Yδ in both of them. In testis and brain, these isozymes at identical pI values showed variable functions with a battery of substrates and the cationic isozymes of brain and testis showed identical properties in CHP (cumene hydroperoxide) at pH values of above 7.0. Substrate specificity studies and immunoblot analysis of testis and brain proteins revealed that they play a predominant role in the detoxication of phenobarbitol or β-methylcholanthrene. Expression of the isozymes in testis and brain on exposure to PB and MC indicated elevated subunit variation. In both testis and brain, Yδ of π class was expressed on PB treatment and Yc of α class and Yβ of μ class was expressed in MC treated testis and only Yc was predominantly expressed in MC treated brain. Thus these subunits expression is considered as markers for carcinogenesis and specific to chemical toxicity under phenobarbitol and β-methylcholanthrene stress. Project supported by Department of Science and Technology and Council for Scientific and Industrial Research, New Delhi  相似文献