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1.
Harleen Mangat Tajamul Hussain C Sundaram MP JS Anandaraj 《Indian journal of clinical biochemistry : IJCB》2002,17(2):74-79
Poly A RNA status and itsin vitro translation in a rabbit reticulolysate cell free system, were assessed in the skeletal muscle of young boys with Duchenne
muscular dystrophy. Compared to normals there is a significant 48% increase in poly A RNA content of dystrophic muscle and
its translatability was increased by 56% based on35S methionine incorporation into total protein systhesised. Immunoprecipitation of the translated products with monospecific
antibodies showed that there is a 2.6 fold and a 2 fold increase in m and μ calpains respectively. This underlines the importance
of both synthetic and degenerative activities in the early pathology in DMD muscle. 相似文献
2.
Roger Bartlett Jon Wheat Matthew Robins 《Sports biomechanics / International Society of Biomechanics in Sports》2013,12(2):224-243
This paper overviews the importance for sports biomechanics of movement variability, which has been studied for some time by cognitive and ecological motor skills specialists but, until quite recently, had somewhat been overlooked by sports biomechanists. The paper considers biomechanics research reporting inter- and intra-individual movement variability in javelin and discus throwing, basketball shooting, and locomotion. The overview does not claim to be comprehensive and we exclude such issues as the theoretical background to movement and coordination variability and their measurement. We overview evidence, both theoretical and empirical, of inter-individual movement variability in seeking to achieve the same task goal, in contrast to the concept of “optimal” movement patterns. Furthermore, even elite athletes cannot reproduce identical movement patterns after many years of training, contradicting the ideas of motor invariance and “representative” trials. We contend that movement variability, far from being solely due to neuromuscular system or measurement “noise” – as sports biomechanists may have previously supposed – is, or could be, functional. Such functionality could allow environmental adaptations, reduce injury risk, and facilitate changes in coordination patterns. We conclude by recommending that sports biomechanists should focus more of their research on movement variability and on important related topics, such as control and coordination of movement, and implications for practice and skill learning. 相似文献
3.
This study examined the extent to which (a) nine US history students developed historically-grounded perspectives, and (b) the entire class engaged itself in inclusive, moral debate about historical events and issues. Inductive methods were used in this micro-ethnographic study to construct and verify its themes though interview, classroom observation and student survey. Seven students demonstrated identifiable perspectives. History was viewed by these students as personally-constructed interpretations, not as value-free chronologies. Only one student's perspective, however, was historically-grounded; other perspectives were grounded in references to contemporary issues. Evidence of moral debate was limited totwo debates observed during 24 classroom observations. These two findings seemed interconnected: students with little historical grounding to their perspectives may have little inclination toward collective, ethical critique. Moral debate consisting of student exchange of diverse historically-grounded perspectives was not the classroom norm. The debates that went into the making of American society concerned not just institutions or governing principles, but the capacity of humans to sustain those institutions. Whatever the disagreements were over other issues at the American Constitutional Convention \[in Philadelphia in 1787], the fundamental question sensed by everyone … was whether the people themselves would understand what it meant to hold the ultimate power of society, and whether they had enough sense of history and destiny to know where they had been and where they ought to be going. (Cousins; cited by Goodlad 1979: 40; emphasis added) 相似文献
5.
Mary Wheat 《The Educational forum》2013,77(3):308-312
In these lines, Lord Tennyson might well have been writing of himself, and the title of the poem from which they are taken, “The Poet of Love,” readily applies to him, for he sang always “a song of undying love, multiplying truth on truth.” That he considered love the all-pervading influence of life is easily deduced from the fact that poem after poem of his has for its theme the immortality of love and its power “to shape or shatter a life till the life shall have fled.” To question whether or not he was the type of writer to deal adequately with the subject is hardly worthwhile since his poems bear silent witness to his artistic ability. Tennyson could have written “as one who loved his fellowmen” since understanding and sympathy such as he has shown in treating with the subject of love are qualities of one whose heart and mind were mellowed by the emotion itself. Love is, as Tennyson himself said in a poem, a more ideal artist than all. 相似文献
6.
Abstract Transverse plane rotations of the upper body are often estimated during the golf swing. The aim of this study was to determine the agreement between upper body alignments measured using markers attached to the thorax and markers on the acromion process during the golf drive. Three-dimensional coordinate data from nine markers were collected (300 Hz) during eight golf drives for 10 participants. The transverse plane alignment of the upper body was calculated using three techniques: inter-acromion vector, thorax vector, and Cardan angles. Agreement between the methods was then assessed using intra-class correlation and 95% limits of agreement. Our results suggested that the thorax vector can be used to provide an accurate estimation of thorax alignment at all stages of the golf swing (R ≥ 0.97, systematic difference < 1.0°, random difference < 3.8°). The inter-acromion vector gave an accurate estimation of thorax alignment at address (R = 0.90, systematic difference = 0.0°, random difference = 4.3°) but it should not be used to estimate thorax alignment at the top of the backswing (R = 0.32, systematic difference = ?16.0°, random difference = 8.7°) or impact (R = 0.90, systematic difference = ?5.1°, random difference = 8.3°) during the golf drive. 相似文献
7.
Zinnia Mitchell-Williams Paul Wilkins Meabh Mclean Wendy Nevin Karyn Wastell Rebecca Wheat 《Educational Action Research》2013,21(3):329-346
This account draws on the experience of five final-year students of human communication and one tutor from the Manchester Metropolitan University who conducted collaborative research into life stages. The research was personally developmental for all those involved and resulted in an increased sense of personal power. The authors discuss the use of their personal development as a research tool, using the models of cooperative inquiry and heuristic inquiry. Ultimately, they consider how their ‘therapeutic’ process can be termed ‘research’, and how their approach can be utilised in research that is personally and socially educational. 相似文献
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9.
Mehdi Kordi Nicos Haralabidis Matthew Huby Paul R. Barratt Glyn Howatson Jon Stephen Wheat 《Journal of sports sciences》2019,37(1):36-41
Gross thigh volume is a key anthropometric variable to predict sport performance and health. Currently, it is either estimated by using the frustum method, which is prone to high inter-and intra-observer error, or using medical imaging, which is expensive and time consuming. Depth camera 3D-imaging systems offer a cheap alternative to measure thigh volume but no between-session reliability or comparison to medical imaging has been made. This experiment established between-session reliability and examined agreement with magnetic resonance imaging (MRI). Forty-eight male cyclists had their thigh volume measured by the depth camera system on two occasions to establish between-session reliability. A subset of 32 participants also had lower body MRIs, through which agreement between the depth camera system and MRI was established. The results showed low between-session variability (CV = 1.7%; Absolute Typical Error = 112 cm3) when measuring thigh volume using the depth camera system. The depth camera systematically measured gross thigh volume 32.6cm3 lower than MRI. These results suggest that depth camera 3D-imaging systems are reliable tools for measuring thigh volume and show good agreement with MRI scanners, providing a cheap and time-saving alternative to medical imaging analysis. 相似文献
10.
Christopher H. Skinner Jade Bennett Robert Richardson Katie Scott Laura S. Wheat James Martinez 《Psychology in the schools》2023,60(1):5-22
School psychologists have been involved with developing and installing individual contingencies designed to remedy individual students' academic deficits. Group-oriented contingencies can be applied to broader efforts designed to prevent learning problems class-wide. Independent group-oriented rewards are frequently used in school settings to enhance learning by rewarding strong academic performance (e.g., reward for each student who maintains a 90% average). Research suggests overreliance on these contingencies may not be educationally equitable because they may be less effective or ineffective in influencing the behavior and learning of students with weaker academic skills. Theoretical and applied research is analyzed which suggests that maintaining ubiquitous independent rewards and providing supplemental interdependent group-oriented bonus rewards may allow educators to a) maintain their academic standards, b) enhance educational equity by improving learning in students who may not respond to typical independent group-oriented rewards, and c) enhance classroom climates. Also, recommendations are provided that may allow educators to mitigate concerns over perceived unfairness associated with interdependent group-oriented rewards. 相似文献