A study of usage of symbols and opinionated words in annotation for modeling literature survey experiences     

Archana Shukla  Banshi D. Chaudhary 《Education and Information Technologies》2015,20(1):91-111

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Assessment of oxidative stress and antioxidant status in age related cataract in a rural population     

A. K. Pradhan  A. K. Shukla  M. V. R. Reddy  N. Garg 《Indian journal of clinical biochemistry : IJCB》2004,19(1):83-87

Oxidative stress was assesed by estimating lipid peroxidation product (LPO) in the form of thiobarbituric acid reactive substances (TBARS), enzymatic antioxidants in the form of superoxide dismutase (SOD), catalase and nonenzymatic antioxidant vitamins e.g. vitamin C, β carotene and vitamin E in either serum or plasma or erythrocytes in 190 cases of age related cataract in the age group of 50–80 years. 190 cases were grouped into three morphological types namely, 73 cases of cortical, 77 cases of posterior subcapsular and 40 cases of nuclear cataract and values of LPO and antioxidants were compared with 78 cases of age matched healthy control groups. Plasma TBARS levels were cataract cases when compared with control groups. There were no significant differences in the erythrocyte levels of catalase and plasma levels of Vit E between cataract cases and control groups. No significant changes of parameters were seen among three different morphological types of age related cataract. The present study shows that the oxidative stress may play an important role in the age related cataract.  相似文献   

A Review on Salivary Genomics and Proteomics Biomarkers in Oral Cancer     

Franky D. Shah  Rasheedunnisa Begum  Bhairavi N. Vajaria  Kinjal R. Patel  Jayendra B. Patel  Shilin N. Shukla  Prabhudas S. Patel 《Indian journal of clinical biochemistry : IJCB》2011,26(4):326-334

Oral cancer has emerged as an alarming public health problem with increasing incidence and mortality rates all over the world. Therefore, the implementation of newer screening and early detection approaches are of utmost importance which could reduce the morbidity and mortality associated with this disease. Sensitive and specific biomarkers for oral cancer are likely to be most effective for screening, diagnosis, staging and follow-up for this dreaded malignancy. Unlike other deep cancers, oral cancer is located in oral cavity. Hence, the direct contact between saliva and oral cancer lesion makes the measurement of tumor markers in saliva an attractive alternative to serum and tissue testing. The DNA, RNA and protein molecules derived from the living cancer cells can be conveniently obtained from saliva. Thus, salivary biomarkers, a non-invasive alternative to serum and tissue-based biomarkers may be an effective modality for early diagnosis, prognostication and monitoring post therapy status. In the current post-genomic era, various technologies provide opportunities for high-throughput approaches to genomics and proteomics; which have been used to evaluate altered expressions of gene and protein targets in saliva of oral cancer patients. The emerging field of salivary biomarkers has great potentials to prove its clinical significance to combat oral cancer. Hence, we have reviewed importance of several salivary genomics and proteomics biomarkers for oral cancer.  相似文献   

Amplitude-modulated sinusoidal microchannels for observing adaptability in C. elegans locomotion     

Parashar A  Lycke R  Carr JA  Pandey S 《Biomicrofluidics》2011,5(2):24112

In this paper, we present a movement-based assay to observe adaptability in Caenorhabditis elegans locomotion behavior. The assay comprises a series of sinusoidal microchannels with a fixed wavelength and modulating (increasing or decreasing) amplitude. The channel width is comparable to the body diameter of the organism. Worms are allowed to enter the channel from the input port and migrate toward the output port. Within channel sections that closely match the worm's natural undulations, the worm movement is relatively quick and steady. As the channel amplitude increases or decreases along the device, the worm faces difficulty in generating the propulsive thrust, begins to slow down and eventually fails to move forward. A set of locomotion parameters (i.e., average forward velocity, number and duration of stops, range of contact angle, and cut-off region) is defined for worm locomotion in modulated sinusoidal channels and extracted from the recorded videos. The device is tested on wild-type C. elegans (N2) and two mutants (lev-8 and unc-38). We anticipate this passive, movement-based assay can be used to screen nematodes showing difference in locomotion phenotype.  相似文献   

A strategy for detection of inconsistency in evaluation of essay type answers     

Archana Shukla  Banshi D. Chaudhary 《Education and Information Technologies》2014,19(4):899-912

The quality of evaluation of essay type answer books involving multiple evaluators for courses with large number of enrollments is likely to be affected due to heterogeneity in experience, expertise and maturity of evaluators. In this paper, we present a strategy to detect anomalies in evaluation of essay type answers by multiple evaluators based on the relationship between marks/grades awarded and symbolic markers, opinionated words recorded in answer books during evaluation. Our strategy is based on the results of our survey with evaluators, analysis of large number of essay type evaluated answer books and our own experiences regarding grievances of students regarding marks/grades. Results of both survey and analysis of evaluated answer books identified underline, tick and cross as frequently used markers compared to circle and question mark. Further, both opinionated words and symbolic markers identified through the survey are used by evaluators to express either positive or negative sentiments. They have differential usage pattern of these symbols as single evaluator and as one amongst multiple evaluators. Tick and cross have well define purposes and have strong correlation with marks awarded. However, the underline marker is being used for dual purpose of expressing both correctness and incorrectness of answers. Our strategy of inconsistency detection first identifies outliers based on the relationship between marks/grades awarded and number of symbols and/or opinionated words used in evaluation. Subsequently, marks and number of symbolic markers of outliers are compared with peer non-outlier answer books having same marks but different number of markers used. Such outlier answer books are termed as anomalous. We discovered 36 anomalies out of total 425 evaluated answer books. We have developed a prototype tool to facilitate online evaluation of answer book and to proactively alert evaluators of possible anomalies.  相似文献   

Quality in Inclusive Preschool Classrooms   总被引：1，自引：1，他引：0  

Linda L. Hestenes  Deborah J. Cassidy  Jonghee Shim  Archana V. Hegde 《Early education and development》2013,24(4):519-540

Research Findings: Quality of care for preschool children in inclusive and noninclusive classrooms was examined in two studies. In Study 1, comparisons across a large sample of classrooms (N = 1, 313) showed that inclusive classrooms were higher than noninclusive classrooms in global quality as well as on two dimensions of quality (Activities/Materials and Language/Interactions). In Study 2, a more diverse sample of 44 classrooms (20 inclusive and 24 noninclusive) did not reveal differences on the global measures of quality but did show a difference on a measure of teacher–child interactions. Teachers in inclusive classrooms had higher quality and more appropriate interactions with all children than did teachers from noninclusive classrooms. Ratings of perceived severity of children's disabilities were not related to any of the measures of classroom quality in either study. Practice or Policy: Both studies suggest that including children with disabilities in regular preschool classrooms does not result in lower quality programs or in less adequate teacher–child interactions, particularly for children with mild to moderate disabilities. Results illustrate the importance of continued education for early childhood professionals on high-quality teacher–child interactions. Faculty in personnel preparation programs as well as policymakers need to continue to promote high-quality interactions between teachers and children.  相似文献   

Cars beyond Otto's internal combustion engines     

A K Shukla 《Resonance》2001,6(11):49-62

Road transportation as an important requirement of modern society is presently faced with restrictions in mainly two respects, namely the ever tightening emission legislation as well as the availability of petroleum fuels, and as a consequence the fuel cost. But in any review of power sources for future road transport vehicles, the performance of the existing internal combustion engine is likely to be the yardstick against which other power sources will be compared. The power sources most likely to provide favourable comparison are those, which can display comparable range and speed, long and reliable life and manufactured at a cost comparable to petrol engine. A vehicle which fails in any of these requirements is unlikely to achieve anything but a niche market share. This article is an appraisal of a variety of proposed electrochemical systems, viz. rechargeable batteries, fuel cells and supercapacitors, for an electric car. It is surmised that a viable electric car could be powered with a fuel cell to provide power for cruising and climbing coupled in parallel with a supercapacitor/battery bank to deliver additional short-term burst-power during acceleration. A K Shukla is a Professor at the Solid State and Structural Chemistry Unit, Indian Institute of Science, Bangalore. His current research interests are in materials electrochemistry with special emphasis on batteries, fuel cells and supercapacitors.  相似文献   

Teacher and Parent Perspectives on Looping     

Archana V. Hegde  Deborah J. Cassidy 《Early Childhood Education Journal》2004,32(2):133-138

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Democratising Teacher Education Research in India     

Caroline Dyer  Archana Choksi  Vinita Awasty  Uma Iyer  Renu Moyade  Neerja Nigam 《比较教育学》2002,38(3):337-351

This paper argues for the need to adopt a more participatory and research-based approach to teacher development in India. Drawing on the experiences of a participatory teacher educator development project in three States, we discuss processes of developing a democratically orientated qualitative research team to work with teachers and teacher educators, highlighting the interplay between their education and socialisation and the demands of the methodology. In the second part of the paper, aspects of developing collaborative action research projects with teacher educators in the context of District Institutes of Education and Training are discussed. Both these approaches require the development of autonomy and critical reflexivity, and although there are tensions in this process, these emerge as vital components of developing a more democratic approach to teacher education.  相似文献   

Energy storage and retrieval     

A. K. Shukla  P. Vishnu Kamath 《Resonance》1996,1(6):61-68

Harnessing sunlight for the production of electrical energy is an engrossing prospect. The crucial concept underlying the success of solar power stations is energy storage and its retrieval on demand which can be most effectively achieved with storage batteries. This article highlights the chemistry of existing and emerging battery technologies.  相似文献