Connecting inside out: Development of the social brain in infants and toddlers with a focus on myelination as a marker of brain maturation     

Nora Schneider  Elizabeth Greenstreet  Sean C. L. Deoni 《Child development》2022,93(2):359-371

Early childhood is a sensitive period for learning and social skill development. The maturation of cerebral regions underlying social processing lays the foundation for later social-emotional competence. This study explored myelin changes in social brain regions and their association with changes in parent-rated social-emotional development in a cohort of 129 children (64 females, 0–36 months, 77 White). Results reveal a steep increase in myelination throughout the social brain in the first 3 years of life that is significantly associated with social-emotional development scores. These findings add knowledge to the emerging picture of social brain development by describing neural underpinnings of human social behavior. They can contribute to identifying age-/stage-appropriate early life factors in this developmental domain.  相似文献   

The Unintentional Effects on Body Donation Programs of a Competency-Based Curriculum in Postgraduate Medical Education     

Geoffroy P.J.C. Noël  Joseph Dubé  Gabriel Venne 《Anatomical sciences education》2021,14(5):675-681

As medical programs place increasing importance on competency-based training and surgical simulations for residents, anatomy laboratories, and body donation programs find themselves in a position of adapting to changing demands. To better assess the demand for “life-like” cadaveric specimens and evaluate the possible impacts that competency-based medical education could have upon the body donation program of McGill University, Canada, the authors tracked, over the course of the last 10 years, the number of soft-embalmed specimens, along with the number of teaching sessions and the residents enrolled in competency-based programs that are using cadaveric material. The results reveal that the number of soft-embalmed specimens used within residency training increased from 5 in 2009 to 35 in 2019, representing an increase from 6% of bodies to 36.5% of the total number of body donors embalmed in this institution. Correspondingly, the number of annual teaching sessions for residents increased from 19 in 2012 to 116 in 2019. These increases in teaching are correlated with increasing number of residents enrolled in competency-based programs over the last 3 years (Pearson r ranging from 0.9705 to 0.9903, and R² ranging from 0.9418 to 0.9808). Those results suggest that the new skill-centered curricula which require residents to perform specific tasks within realistic settings, exhibit a growing demand for “life-like” cadaveric specimens. Institutions’ body donation programs must, therefore, adapt to those greater need for cadaveric specimens, which presents many challenges, ranging from the logistical to the ethical.  相似文献   

Early Childhood Parenting Predicts Late Childhood Brain Functional Connectivity During Emotion Perception and Reward Processing     

Daniel C. Kopala-Sibley  Marilyn Cyr  Megan C. Finsaas  Jonathan Orawe  Anna Huang  Nim Tottenham  Daniel N. Klein 《Child development》2020,91(1):110-128

Seventy-nine 3-year olds and their mothers participated in a laboratory-based task to assess maternal hostility. Mothers also reported their behavioral regulation of their child. Seven years later, functional magnetic resonance imaging data were acquired while viewing emotional faces and completing a reward processing task. Maternal hostility predicted more negative amygdala connectivity during exposure to sad relative to neutral faces with frontal and parietal regions as well as more negative left ventral striatal connectivity during monetary gain relative to loss feedback with the right posterior orbital frontal cortex and right inferior frontal gyrus. In contrast, maternal regulation predicted enhanced cingulo-frontal connectivity during monetary gain relative to loss feedback. Results suggest parenting is associated with alterations in emotion and reward processing circuitry 7–8 years later.  相似文献   

Does modality matter? A latent profile and transition analysis of sedentary behaviours among school-aged youth: The UP&DOWN study     

David Sánchez-Oliva  Rebecca M. Leech  Alberto Grao-Cruces  Irene Esteban-Cornejo  Carmen Padilla-Moledo  Oscar L. Veiga 《Journal of sports sciences》2020,38(9):1062-1069

ABSTRACT

The aims of this study were to identify profiles of sedentary behaviour (SB) patterns, based on leisure-time self-reported SB modalities (screen, educative, social, and relaxing) and to evaluate changes in these profiles over 2 years among Spanish youth aged 8–18 years. Latent profile analysis (LPA), a data-driven analytic approach, was used to identify groups of boys and girls (n = 1553; 48% girls; mean±SD age: 12.56 ± 2.49 y) with distinct SB profiles using the SB modalities (time/d) as input variables. Latent transition analysis, an extension of LPA that uses longitudinal data, was used to analyse 2-year changes in these profiles. At baseline, four and three SB profiles were found among boys (labelled: screen, educative, social, and relaxing) and girls (labelled: screen/social, educative, and relaxing), respectively. Overall, more girls (range: 48%-67%) had the same profile over time, than boys (40%-52%). Participants with a screen or relaxing SB profile at baseline were more likely to have an educative profile after 2 years. Youth with a social and an educative SB profile at baseline were more likely to transition to profiles characterized by higher screen and social SB, respectively. Using a novel and person-centered approach, this study identified gender-specific SB profiles that were moderately stable over time.  相似文献   

‘Just stick to the science’ is not enough     

Peterson  Erik L. 《Metascience》2019,28(1):147-150

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Digital Module 16: Longitudinal Data Analysis     

Jeffrey R. Harring  Tessa L. Johnson 《Educational Measurement》2020,39(3):137-138

In this digital ITEMS module, Dr. Jeffrey Harring and Ms. Tessa Johnson introduce the linear mixed effects (LME) model as a flexible general framework for simultaneously modeling continuous repeated measures data with a scientifically defensible function that adequately summarizes both individual change as well as the average response. The module begins with a nontechnical overview of longitudinal data analyses drawing distinctions with cross-sectional analyses in terms of research questions to be addressed. Nuances of longitudinal designs, timing of measurements, and the real possibility of missing data are then discussed. The three interconnected components of the LME model—(1) a model for individual and mean response profiles, (2) a model to characterize the covariation among the time-specific residuals, and (3) a set of models that summarize the extent that individual coefficients vary—are discussed in the context of the set of activities comprising an analysis. Finally, they demonstrate how to estimate the linear mixed effects model within an open-source environment (R). The digital module contains sample R code, diagnostic quiz questions, hands-on activities in R, curated resources, and a glossary.  相似文献   

The Influence of Hygroscopic Materials on the Fluctuation of Relative Humidity in Museums Located in Historical Buildings     

C. Ferreira  V. P. de Freitas 《文物保护研究》2020,65(3):127-141

ABSTRACT

The preservation of artefacts in museum collections is profoundly affected by fluctuations in temperature and, especially, relative humidity (RH). Since the late nineteenth century, many studies have been carried out on the best way to control hygrothermal conditions. In old buildings located in maritime temperate climate zones (such as Portugal) with strong thermal inertia, and which have low ventilation rate (relative to the volume and number of visitors), daily and seasonal hygroscopic inertia may help to assure the maintenance of RH stabilization conditions. The use of expensive active systems may be minimized through the passive behaviour of internal finishing building materials. This work presents the results of an experimental laboratory study conducted in a flow chamber to demonstrate the enormous potential of hygroscopic materials in stabilizing interior relative humidity. Based in these results and in-situ monitoring in a museum housed in a building, located in Porto, with a typical construction of the 1950s (granite masonry and reinforced concrete slabs), a numerical analysis was done to quantify the influence of hygroscopic materials in stabilizing the interior relative humidity.  相似文献   

Proclaiming Library Worth in a Program Prioritization Process at a Mid-Sized Public University     

Michelle J. Oh  Robin J. Harris  Lisa C. Wallis 《图书馆管理杂志》2020,60(3):250-262

Abstract

In an economic climate when colleges can no longer presume that legislators see institutions of higher learning as tacit public goods, institutions around the country are facing budget cuts. This article presents a case study of the experience of a mid-sized public state university and its Library in a budget crisis undergoing a university-wide program prioritization process. The authors review the process of writing three reports on the Library’s value, along with the approach to engaging staff in the process including a retreat. This article raises questions about what every library should consider assessing and provide tools for libraries navigating similar terrain.  相似文献   

中国竞技体育人力资源相关问题探讨   总被引：5，自引：0，他引：5  

肖林鹏  赵云宏  张兆青  骆意 《广州体育学院学报》2003,23(6):8-9

对竞技体育人力资源的概念、特点等问题进行了探讨：研究表明，竞技体育人力资源是指竞技体育发展所需人员的现实及潜在禀赋的总和。处于不同层次、不同领域的众多人员组成了竞技体育人力资源系统：竞技人力资源具有稀缺性、目标性、整体性及调控性等特点.  相似文献   

国内运动生物力学发展现状思考   总被引：5，自引：0，他引：5  

王今越  刘伟  陈民盛 《天津体育学院学报》2003,18(4):33-36

运动生物力学是一门新兴的边缘性科学，其定义、研究范畴、研究方法都有待商榷。从这三个角度出发，主要对大量资料进行归纳总结，综合、概括了目前国内运动生物力学发展状况。力求对我国的运动生物力学发展的状况勾勒出一个清晰的脉络图，以便在这门学科今后的研究中减少盲目性，具有更强的实用性。  相似文献